Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Alisa W Serio"'
Autor:
Elisa H. Ignatius, Binayak Rimal, Chandra M. Panthi, Daniel C. Belz, Christopher K. Lippincott, Daniel H. Deck, Alisa W. Serio, Gyanu Lamichhane
Publikováno v:
mSphere, Vol 9, Iss 7 (2024)
ABSTRACT Treatment outcomes for Mycobacteroides abscessus (Mab, also known as Mycobacterium abscessus) disease are still unsatisfactory, mainly due to issues with drug toxicity, tolerability, and efficacy. Treating Mab disease is challenging due to i
Externí odkaz:
https://doaj.org/article/7ccb62dd0f5245f68304d89d92fc27f0
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37310 (2012)
Despite recent advances in our ability to genetically manipulate Rickettsia, little has been done to employ genetic tools to study the expression and localization of Rickettsia virulence proteins. Using a mariner-based Himar1 transposition system, we
Externí odkaz:
https://doaj.org/article/350d6c1e386a45618df680952a2fee98
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 30, Iss , Pp 96-99 (2022)
ABSTRACT: Objectives: Antibiotics are associated with increased risk of Clostridioides difficile infection, which has limited treatment options. We assessed in vitro activity of omadacycline (an aminomethylcycline antibiotic) against the C. difficile
Externí odkaz:
https://doaj.org/article/061fc20000c14acfb1c1d713fad6c482
Autor:
Binayak Rimal, Danielle A. Nicklas, Chandra M. Panthi, Christopher K. Lippincott, Daniel C. Belz, Elisa H. Ignatius, Daniel H. Deck, Alisa W. Serio, Gyanu Lamichhane
Publikováno v:
mSphere, Vol 8, Iss 2 (2023)
ABSTRACT Mycobacteroides abscessus is an opportunistic pathogen in people with structural lung conditions such as bronchiectasis, chronic obstructive pulmonary disease, and cystic fibrosis. Pulmonary M. abscessus infection causes progressive symptoma
Externí odkaz:
https://doaj.org/article/69dd87c747fd41cdb82da060a9dfed37
Publikováno v:
Annals of Pharmacotherapy. 57:184-192
Objective The objective of this systematic review is to summarize in vitro, preclinical, and human data related to omadacycline and Clostridioides difficile infection (CDI). Data Sources PubMed and Google Scholar were searched for “omadacycline”
Publikováno v:
The Annals of pharmacotherapy.
The objective of this systematic review is to summarize in vitro, preclinical, and human data related to omadacycline andPubMed and Google Scholar were searched for "omadacycline" AND ("Publications presenting primary data on omadacycline andPreclini
Autor:
Tiffany R Keepers, Suzannah M. Schmidt-Malan, Robin Patel, Alisa W Serio, Melissa J. Karau, Bobbi S. Pritt, Surya Chitra, Scott A. Cunningham, Jayawant N. Mandrekar
Publikováno v:
Antimicrobial Agents and Chemotherapy
Omadacycline, vancomycin, and rifampin, as well as rifampin combination therapies, were evaluated in an experimental rat model of methicillin-resistant Staphylococcus aureus (MRSA) osteomyelitis. All treatment groups had less MRSA recovered than sali
Publikováno v:
JAC-Antimicrobial Resistance
Objectives To evaluate the effect of sub-growth-inhibitory concentrations of omadacycline on Staphylococcus aureus ATCC 10832 haemolytic activity in vitro. Methods Following determination of the MICs of omadacycline and comparator antibiotics, the st
Autor:
Danielle A, Nicklas, Emily C, Maggioncalda, Elizabeth, Story-Roller, Benjamin, Eichelman, Chavis, Tabor, Alisa W, Serio, Tiffany R, Keepers, Surya, Chitra, Gyanu, Lamichhane
Publikováno v:
Antimicrobial Agents and Chemotherapy
The incidence of nontuberculous mycobacterial diseases in the United States is rising and has surpassed that of tuberculosis. Most notable among the nontuberculous mycobacteria is Mycobacteroides abscessus, an emerging environmental opportunistic pat
Autor:
Frederick Cohen, James B. Aggen, Logan D. Andrews, Zahra Assar, Jen Boggs, Taylor Choi, Paola Dozzo, Ashton N. Easterday, Cat M. Haglund, Darin J. Hildebrandt, Melissa C. Holt, Kristin Joly, Adrian Jubb, Zeeshan Kamal, Timothy R. Kane, Andrei W. Konradi, Kevin M. Krause, Martin S. Linsell, Timothy D. Machajewski, Olga Miroshnikova, Heinz E. Moser, Vincent Nieto, Thu Phan, Craig Plato, Alisa W. Serio, Julie Seroogy, Anton Shakhmin, Adam J. Stein, Alex D. Sun, Serguei Sviridov, Zhan Wang, Kenneth Wlasichuk, Wen Yang, Xiaoming Zhou, Hai Zhu, Ryan T. Cirz
Publikováno v:
ChemMedChem. 14:1560-1572
UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC) is a Zn