Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alisa Truong"'
Autor:
Josh Tycko, Michael Wainberg, Georgi K. Marinov, Oana Ursu, Gaelen T. Hess, Braeden K. Ego, Aradhana, Amy Li, Alisa Truong, Alexandro E. Trevino, Kaitlyn Spees, David Yao, Irene M. Kaplow, Peyton G. Greenside, David W. Morgens, Douglas H. Phanstiel, Michael P. Snyder, Lacramioara Bintu, William J. Greenleaf, Anshul Kundaje, Michael C. Bassik
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Off-target effects in CRISPR screens for essential regulatory elements have not been systematically evaluated. Here the authors find Cas9 nuclease, CRISPRi/a each have distinct off-target effects, and that these can be accurately identified and remov
Externí odkaz:
https://doaj.org/article/fc5611c303ab470e9fff314f00d1301c
Autor:
Peyton Greenside, Georgi K. Marinov, Josh Tycko, Alisa Truong, Irene M. Kaplow, Michael Wainberg, Lacramioara Bintu, Aradhana, Braeden K. Ego, David W. Morgens, Amy Li, Oana Ursu, Kaitlyn Spees, William J. Greenleaf, Anshul Kundaje, Michael Snyder, Gaelen T. Hess, Douglas H. Phanstiel, David Yao, Alexandro E. Trevino, Michael C. Bassik
Publikováno v:
Nature communications, vol 10, iss 1
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Pooled CRISPR-Cas9 screens are a powerful method for functionally characterizing regulatory elements in the non-coding genome, but off-target effects in these experiments have not been systematically evaluated. Here, we investigate Cas9, dCas9, and C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e325fcff4cd3eaeeca1f951b131ee713
https://escholarship.org/uc/item/4fz6d76z
https://escholarship.org/uc/item/4fz6d76z
Autor:
Liang, Yi-Lynn, Khoshouei, Maryam, Deganutti, Giuseppe, Glukhova, Alisa, Koole, Cassandra, Peat, Thomas S., Radjainia, Mazdak, Plitzko, Jürgen M., Baumeister, Wolfgang, Miller, Laurence J., Hay, Deborah L., Christopoulos, Arthur, Reynolds, Christopher A., Wootten, Denise, Sexton, Patrick M.
Publikováno v:
Nature; Sep2018, Vol. 561 Issue 7724, p492-497, 6p, 10 Diagrams, 4 Graphs
Autor:
Tycko, Josh, Wainberg, Michael, Marinov, Georgi K., Ursu, Oana, Hess, Gaelen T., Ego, Braeden K., Aradhana, Li, Amy, Truong, Alisa, Trevino, Alexandro E., Spees, Kaitlyn, Yao, David, Kaplow, Irene M., Greenside, Peyton G., Morgens, David W., Phanstiel, Douglas H., Snyder, Michael P., Bintu, Lacramioara, Greenleaf, William J., Kundaje, Anshul
Publikováno v:
Nature Communications; 9/6/2019, Vol. 10 Issue 1, pN.PAG-N.PAG, 1p