Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Alisa Savchenko"'
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 182 (2024)
In the skin, estradiol (E2) promotes profibrotic and proinflammatory cytokines, contributing to extracellular matrix (ECM) deposition. However, the magnitude of the response differs. Using the human skin organ culture model, we evaluated donor charac
Externí odkaz:
https://doaj.org/article/54b005e603cb4a059750b186aba1f968
Autor:
DeAnna Baker Frost, Alisa Savchenko, Adeyemi Ogunleye, Milton Armstrong, Carol Feghali-Bostwick
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-10 (2021)
Abstract Background Both TGFβ and estradiol (E2), a form of estrogen, are pro-fibrotic in the skin. In the connective tissue disease, systemic sclerosis (SSc), both TGFβ and E2 are likely pathogenic. Yet the regulation of TGFβ in E2-induced dermal
Externí odkaz:
https://doaj.org/article/9319fbf2e1974e6ab9cdb5abb7e6fcb0