Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alisa P. Hetrick"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7343 (2022)
Combining aminoglycosides and loop diuretics often serves as an effective ototoxic approach to deafen experimental animals. The treatment results in rapid hair cell loss with extended macrophage presence in the cochlea, creating a sterile inflammator
Externí odkaz:
https://doaj.org/article/7a932662409049808584be66755bb40d
Autor:
Alisa P. Hetrick, Timothy T. K. Jung, Hao Wu, Jessica G. Gonzalez, Hongzhe Li, Weiwei He, Liana Sargsyan, Weiqiang Yang, Yongchuan Chai
Publikováno v:
The Laryngoscope
OBJECTIVES/HYPOTHESIS Lipopolysaccharide (LPS), a key component of bacterial endotoxins, activates macrophages and triggers the release of inflammatory cytokines in mammalian tissues. Recent studies have shown that intratympanic injection of LPS simu
Autor:
Jessica G. Gonzalez, Alisa P. Hetrick, Glen K. Martin, Liana Sargsyan, Hongzhe Li, Marjorie R. Leek
Publikováno v:
NeuroToxicology. 84:73-83
It is well-established that aminoglycoside antibiotics are ototoxic, and the toxicity can be drastically enhanced by the addition of loop diuretics, resulting in rapid irreversible hair cell damage. Using both electrophysiologic and morphological app
Publikováno v:
The Journal of the Acoustical Society of America. 144:1834-1834
Cochlear inflammatory response to various environmental insults, has been increasingly become a topic of interest. As the immune response is associated with both pathology and protection, targeting specific components of the immune response is expect