A PD‐1highCD4+ T Cell Population With a Cytotoxic Phenotype is Associated With Interstitial Lung Disease in Systemic Sclerosis

Autor: Mehreen Elahee, Alisa A. Mueller, Runci Wang, Kathryne E. Marks, Takanori Sasaki, Ye Cao, Andrea Fava, Paul F. Dellaripa, Francesco Boin, Deepak A. Rao

Publikováno v: ACR Open Rheumatology, Vol 6, Iss 7, Pp 429-439 (2024)

Objective T cells contribute to tissue injury in systemic sclerosis (SSc), yet the specific T cell subsets expanded in patients with SSc remain incompletely defined. Here we evaluated specific phenotypes and functions of peripheral helper T (Tph) and

Externí odkaz: https://doaj.org/article/f28238a6fae84f978ff2cf2458dae924

Macrophage-released ADAMTS1 promotes muscle stem cell activation

Autor: Hongqing Du, Chung-Hsuan Shih, Michael N. Wosczyna, Alisa A. Mueller, Joonseok Cho, Abhishek Aggarwal, Thomas A. Rando, Brian J. Feldman

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)

Satellite cells are crucial for growth and regeneration of skeletal muscle. Here the authors show that in response to muscle injury, macrophages secrete Adamts1, which induces satellite cell activation by modulating Notch1 signaling.

Externí odkaz: https://doaj.org/article/b985b4346d2b4425bb7a38b75908eb78

Protocol for assessing and predicting acute respiratory decline in hospitalized patients

Autor: Louis T. Merriam, Alisa A. Mueller, Conor P. Crowley, Tomoyoshi Tamura, Hibah Haider, Edy Y. Kim, Justin D. Salciccioli, Jeremy R. DeGrado

Publikováno v: STAR Protocols
STAR Protocols, Vol 2, Iss 2, Pp 100545-(2021)

Summary This protocol aids both new and experienced researchers in designing retrospective clinical and translational studies of acute respiratory decline in hospitalized patients. This protocol addresses (1) the basics of respiratory failure and ele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84272c20e2e1c8ff8a7182be2abff3ed
https://pubmed.ncbi.nlm.nih.gov/34027496

Inflammatory Biomarker Trends Predict Respiratory Decline in COVID-19 Patients

Autor: Anthony F. Massaro, Conor P. Crowley, Tomoyoshi Tamura, Erin Hazel Penn, Edy Y. Kim, Julia L. Jezmir, Alisa A. Mueller, Jeremy R. DeGrado, Gregory Keras, Hibah Haider

Publikováno v: Cell Reports Medicine
Cell Reports. Medicine

In this single-center, retrospective cohort analysis of hospitalized coronavirus disease 2019 (COVID-19) patients, we investigate whether inflammatory biomarker levels predict respiratory decline in patients who initially present with stable disease.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0e4647656f33860c9d7c49dc7f02f0

Identification of Racial Inequities in Access to Specialized Inpatient Heart Failure Care at an Academic Medical Center

Autor: Catherine Meador, Viswatej Avutu, Emily Cetrone, Alec Petersen, Alexander B. Stone, George Huang, Rebecca Zon, Aaron J. Cohen, Aileen Wright, Jacqueline Greb, Sam A. Tanyos, Thomas Gilliland, Sheridan Reiger, David B. Duong, Alissa Cooper, An Tran, Michelle Rengarajan, Pablo Sanchez, Robert J. Glynn, Kenneth Barshop, Aaron J. Deutsch, Christine E. Ryan, Heather Burrell Ward, Molly Plovanich, Siobhan Case, Mark Ferreira, Chijioke Nze, Rose M. Kakoza, Justin Tuwatananurak, Steven M. Blum, Zachary Hermes, Hans Stabenau, Yi Lu, Elisa Walsh, Bradford Diephuis, Anish Mehta, Alexander P. Boardman, Jennifer Schulte, Daniel C. Pipilas, Laura Kolbe, Hallie Rozansky, Stephanie Lin-Beckford, Alexandra Charrow, Khameer Kidia, Matthew E. Growdon, Joshua Lang, Lindsay N. Warner, Eleni Stavrou, Caroline Wunsch, Andrew Ben Shorten, James W. Smithy, Evan Shannon, Michael Pardo, Wai-Ying Yau, Caitlin Drescher, Natalie Fedotova, Patricia Foo, Michelle Morse, Kristine Torres-Lockhart, Ramkumar V. Venkateswaran, Stephen Tsaur, Mariel Bailey, Cristina Thomas, Andrew Stergachis, Abraar Karan, Eldrin F. Lewis, Tamara Feingold-Link, Sanjay Salgado, Sungat Grewal, Mariya Kalashnikova, Kevin Ma, Devin Worster, Marisa L. Winkler, Gregory Snyder, Brian W. Powers, Stanley Jablonski, Jennifer Yeh, Joseph Loscalzo, Kaeleen Boden, Joel T. Katz, Julia Beamesderfer, Douglas Jacobs, Stephanie Rico, Nareh Marukian, Lauren Sinnenberg, Sohan Japa, Zachary Lee, Emily Murphy, Siddharth Patel, Aaron Richterman, Robert Boxer, Anna Reichardt, Wilfredo R. Matias, Christine A. Eckhardt, Jyotsna Mullur, Priscilla Wang, Cindy Y. Chang, Alexandra Bachorik, Omar Bayomy, Katherine J. Greco, Cynthia K. Hahn, Maria A Yialamas, Emilie Mitten, Diana Lopez, Michael B. Foote, Neha Limaye, Katherine C. Brooks, Erika J Haydu, Robert S. Stern, Erik Andrews, Emily Baumrin, Julia Loewenthal, Neil Shaw, Idil Kore, Melissa G. Lechner, Richard W. Joseph, Jessica S. Little, Alexis Roy, Nina Jain, Jamila Wynter, Lindsay Wahl, Scott M Knowles, Constantinos Michaelidis, Nicholas Yozamp, Laura Horton, Jordan Wengrod, Sarah Brown, Michael McLaughlin, Meghan Rudder, Ranjani Logaraj, Haley Thun, Noreen Okwara, Daniel Kellner, Lauren A. Eberly, Anastasia Vishnevetsky, Ayrenne Adams, Ian McConnell, Denis Balaban, Scott Lee, Erica Pimenta, Nicholas S. Downing, Matthew Lawlor, Sarah Royston, Anirudh Sreekrishnan, Salina Bakshi, Marina Zambrotta, Zachary E. Holcomb, Frances Wallace, Tomas Cordova, Kathryn B. Holroyd, Rafael Paez, Christina Meade, Daniel Loriaux, Devin Clark, Omar Badri, Anita Rao, Alisa A. Mueller, Shervin Tabrizi, David D. Berg, Yiannis Koullias, Ifedayo O. Kuye, Nora Becker, Daniel Kang, Herrick N Fisher, Kay Everett, Rachael Rosales, C. Nicholas Cuneo, Peter Dorschner, Abirami Natarajan, Jeffrey L. Wong, Kristin M. D’Silva, Samantha Abel, Lisa S. Rotenstein, Brendan John Guercio, Geneva DeGregorio, June-Ho Kim, Benjamin Grin, Ross England, Mattheus Ramsis, Emily C. Cleveland Manchanda, Alsina Alejandro de Feria, Daniel Yazdi, Sanjay Divakaran, Frederick D. Tsai, Haiyan Ramirez Batlle, Bram Wispelwey, Robert A. Bonacci, April Wall, Denise Pong, Idalid Franco, Michelle Nsahlai, Chase Yarbrough, Carolyn Treasure, Lachelle D. Weeks, Joseph Anaya, Benjamin Atkinson, Jennifer Goldsmith, Jessica N. Williams, Brian Hasselfeld, Ellen H. Nagami, Katie Baird, Evan Tschirhart, Berman Adam N., Jared R. Mayers, Peter Olds, Ken Lee, Scott A. Elman, Neil Kalwani, David Y. Chiang, Kipp Weiskopf, Regan H. Marsh, Jacob Mirsky, Kirsti Campbell, William Shrauner, Elizabeth Messenger, Anne G. Beckett, Marla Lipsyc, Aswin Sekar, Benjamin N. Rome, Sarah E. Earp, Nicholas P. Semenkovich, Karen Deffenbacher, Laura Phelan, Ersilia M. DeFilippis, Gordon Hildick-Smith, Amir Munir, Peter Dunbar

Publikováno v: Circ Heart Fail

Background: Racial inequities for patients with heart failure (HF) have been widely documented. HF patients who receive cardiology care during a hospital admission have better outcomes. It is unknown whether there are differences in admission to a ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd9aa854feec0d29183c6853aee91a5f
https://europepmc.org/articles/PMC7183732/