Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Alisa A, Shaimardanova"'
Autor:
Alisa A Shaimardanova, Daria S Chulpanova, Valeriya V Solovyeva, Aleksandr M Aimaletdinov, Albert A Rizvanov
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 1, Pp 122-129 (2022)
Tay-Sachs disease and Sandhoff disease are severe hereditary neurodegenerative disorders caused by a deficiency of β-hexosaminidase A (HexA) enzyme, which results in the accumulation of GM2 gangliosides in the nervous system cells. In this work, we
Externí odkaz:
https://doaj.org/article/0097f804bf2b4a5c8c308f75b30f561c
Publikováno v:
Cells, Vol 12, Iss 5, p 785 (2023)
Despite scientific discoveries in the field of gene and cell therapy, some diseases still have no effective treatment. Advances in genetic engineering methods have enabled the development of effective gene therapy methods for various diseases based o
Externí odkaz:
https://doaj.org/article/882ac81ad6b6474281814554af5ebc2e
Autor:
Alisa A. Shaimardanova, Daria S. Chulpanova, Aysilu I. Mullagulova, Zaid Afawi, Rimma G. Gamirova, Valeriya V. Solovyeva, Albert A. Rizvanov
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Epilepsy is a chronic non-infectious disease of the brain, characterized primarily by recurrent unprovoked seizures, defined as an episode of disturbance of motor, sensory, autonomic, or mental functions resulting from excessive neuronal discharge. D
Externí odkaz:
https://doaj.org/article/84cccb3a07124726864778685cc51221
Autor:
Shaza S. Issa, Alisa A. Shaimardanova, Victor V. Valiullin, Albert A. Rizvanov, Valeriya V. Solovyeva
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Lysosomal storage diseases (LSDs) are a group of approximately 50 genetic disorders caused by mutations in genes coding enzymes that are involved in cell degradation and transferring lipids and other macromolecules. Accumulation of lipids and other m
Externí odkaz:
https://doaj.org/article/b8c132929c9c4a229482274058d5ca2a
Autor:
Alisa A Shaimardanova, Valeriya V Solovyeva, Daria S Chulpanova, Victoria James, Kristina V Kitaeva, Albert A Rizvanov
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 4, Pp 586-596 (2020)
Extracellular vesicles, including exosomes and microvesicles, play a fundamental role in the activity of the nervous system, participating in signal transmission between neurons and providing the interaction of central nervous system with all body sy
Externí odkaz:
https://doaj.org/article/da367b716f0543cf8616504b87303157
Autor:
Alisa A. Shaimardanova, Daria S. Chulpanova, Valeriya V. Solovyeva, Aysilu I. Mullagulova, Kristina V. Kitaeva, Cinzia Allegrucci, Albert A. Rizvanov
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Metachromatic leukodystrophy is a lysosomal storage disease, which is characterized by damage of the myelin sheath that covers most of nerve fibers of the central and peripheral nervous systems. The disease occurs due to a deficiency of the lysosomal
Externí odkaz:
https://doaj.org/article/cc5e023c74c342fdb7e5f7ad0b3c0165
Autor:
Alisa A. Shaimardanova, Daria S. Chulpanova, Valeriya V. Solovyeva, Ekaterina E. Garanina, Ilnur I. Salafutdinov, Alexander Vladimirovich Laikov, Vadim V. Kursenko, Lisa Chakrabarti, Ekaterina Yu. Zakharova, Tatiana M. Bukina, Galina V. Baydakova, Albert Anatolyevich Rizvanov
Publikováno v:
Life, Vol 11, Iss 10, p 1007 (2021)
Tay-Sachs disease (TSD) is a progressive neurodegenerative disorder that occurs due to a deficiency of a β hexosaminidase A (HexA) enzyme, resulting in the accumulation of GM2 gangliosides. In this work, we analyzed the effect of umbilical cord bloo
Externí odkaz:
https://doaj.org/article/081f47a5b4b74e2ebf1cd22c85c1c8d1
Autor:
Valeriya V. Solovyeva, Alisa A. Shaimardanova, Daria S. Chulpanova, Kristina V. Kitaeva, Lisa Chakrabarti, Albert A. Rizvanov
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Tay-Sachs disease belongs to the group of autosomal-recessive lysosomal storage metabolic disorders. This disease is caused by β-hexosaminidase A (HexA) enzyme deficiency due to various mutations in α-subunit gene of this enzyme, resulting in GM2 g
Externí odkaz:
https://doaj.org/article/9f9bc835e2414b2699027f94ede7864d
Autor:
Alisa A. Shaimardanova, Kristina V. Kitaeva, Ilmira I. Abdrakhmanova, Vladislav M. Chernov, Catrin S. Rutland, Albert A. Rizvanov, Daria S. Chulpanova, Valeriya V. Solovyeva
Publikováno v:
Pharmaceutics, Vol 11, Iss 11, p 580 (2019)
The development of multicistronic vectors has opened up new opportunities to address the fundamental issues of molecular and cellular biology related to the need for the simultaneous delivery and joint expression of several genes. To date, the exampl
Externí odkaz:
https://doaj.org/article/8ccb7940569849cabdef3ca8ea7ee834
Autor:
Daria S. Chulpanova, Valeriya V. Solovyeva, Albert A. Rizvanov, Alisa A. Shaimardanova, Kristina V. Kitaeva
Publikováno v:
Genes & Cells. 15:17-22
Tay-Sachs disease (OMIM 272800) belongs to the group of autosomal-recessive disorders, caused by p-hexosaminidase A (HexA) enzyme deficiency, resulting in GM2-ganglioside accumulation in nervous and other tissues of the body. Enzyme deficiency is cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e768b941e7aa95681536953e4a24104e
https://doi.org/10.23868/202003002
https://doi.org/10.23868/202003002