Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Alis, Ilie"'
Autor:
Coralie Schoumacher, Valentin Derangère, Gwladys Gaudillière-Le Dain, Titouan Huppe, David Rageot, Alis Ilie, Angélique Vienot, Christophe Borg, Franck Monnien, Frederic Bibeau, Caroline Truntzer, François Ghiringhelli
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTStratification of the prognosis of pancreatic cancer (PDAC) patients treated by surgery is based solely on clinical variables, such as tumor stage and node status. The development of biomarkers of relapse is needed, especially to drive admini
Externí odkaz:
https://doaj.org/article/d7de998b11554bb3986b1833080f8892
Autor:
Nicolas Roussot, Marion Thibaudin, Jean-David Fumet, Susy Daumoine, Léa Hampe, Cédric Rébé, Emeric Limagne, Aurélie Lagrange, Victor Herreros, Julie Lecuelle, Hugo Mananet, Alis Ilie, David Rageot, Romain Boidot, Vincent Goussot, Anthony Comte, Pierre Jacob, Françoise Beltjens, Anthony Bergeron, Céline Charon-Barra, Laurent Arnould, Valentin Derangère, Sylvain Ladoire, Caroline Truntzer, François Ghiringhelli
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
A patient with a PD-L1-negative, TMB-low, KEAP1/STK11 co-mutated metastatic non-small cell lung cancer (NSCLC) experienced a multisite radiological progression at 3 months after initiation of chemoimmunotherapy as first-line treatment for metastatic
Externí odkaz:
https://doaj.org/article/720f9ebdb12b41d5a9b653e489118e2d
Autor:
Julie Lecuelle, Caroline Truntzer, Debora Basile, Luigi Laghi, Luana Greco, Alis Ilie, David Rageot, Jean-François Emile, Fréderic Bibeau, Julien Taïeb, Valentin Derangere, Come Lepage, François Ghiringhelli
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105207- (2024)
Summary: Background: T-cell immune infiltrates are robust prognostic variables in localised colon cancer. Evaluation of prognosis using artificial intelligence is an emerging field. We evaluated whether machine learning analysis improved prediction o
Externí odkaz:
https://doaj.org/article/f4866831da2d49b389ebad9f61f0d2b7
Autor:
Silvia Mihaela Ilie, Nathalie Briot, Guillaume Constatin, Alis Ilie, Francoise Beltjens, Sylvain Ladoire, Isabelle Desmoulins, Audrey Hennequin, Aurelie Bertaut, Charles Coutant, Sylvain Causeret, Niama Ghozali, Bruno Coudert, Laurent Arnould
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
BackgroundThe persistence of residual tumour after neoadjuvant chemotherapy (NAC) in localised triple-negative breast cancer (TNBC) is known to have a negative prognostic value. However, different degrees of expression of some immunohistochemical mar
Externí odkaz:
https://doaj.org/article/5f0054ccd4204d3ba672b7ef8f850799
Autor:
Zoé Tharin, Corentin Richard, Valentin Derangère, Alis Ilie, Laurent Arnould, François Ghiringhelli, Romain Boidot, Sylvain Ladoire
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract There is little data concerning the implications of PIK3CA mutations outside of the known hotspots described in ER+/HER2− metastatic breast cancer (mBC). Similarly, PIK3R1 mutations could also lead to activation of PI3K pathway, but are po
Externí odkaz:
https://doaj.org/article/549ad5585730463788e76a11767d4dba
Autor:
François Ghiringhelli, Frederic Bibeau, Laurent Greillier, Jean-David Fumet, Alis Ilie, Florence Monville, Caroline Laugé, Aurélie Catteau, Isabelle Boquet, Amine Majdi, Erwan Morgand, Youssef Oulkhouir, Nicolas Brandone, Julien Adam, Thomas Sbarrato, Alboukadel Kassambara, Jacques Fieschi, Stéphane Garcia, Anne Laure Lepage, Pascale Tomasini, Jérôme Galon
Publikováno v:
EBioMedicine, Vol 92, Iss , Pp 104633- (2023)
Summary: Background: Anti-PD-1 and PD-L1 antibodies (mAbs) are approved immunotherapy agents to treat metastatic non-small cell lung cancer (NSCLC) patients. Only a minority of patients responds to these treatments and biomarkers predicting response
Externí odkaz:
https://doaj.org/article/af4bad0461854aff8dc0c5518a34fcbc
Autor:
Anne Laure Le Page, Elise Ballot, Caroline Truntzer, Valentin Derangère, Alis Ilie, David Rageot, Frederic Bibeau, Francois Ghiringhelli
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Histological stratification in metastatic non-small cell lung cancer (NSCLC) is essential to properly guide therapy. Morphological evaluation remains the basis for subtyping and is completed by additional immunohistochemistry labelling to co
Externí odkaz:
https://doaj.org/article/74ac5820612a46008b10fb9d90971185
Autor:
Francois Ghiringhelli, Emeric Limagne, Thomas Pilot, Aurélie Fratti, Chloé Thinselin, Anaïs Perrichet, Lucie Demontoux, Alis Ilie, Mané Ndiaye, Elise Jacquin, Carmen Garrido, Fanny Chalmin, Cédric Rébé
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background We have previously shown that 5-fluorouracil (5-FU) selectively kills myeloid-derived suppressor cells (MDSCs) and activates NLRP3 (NOD-leucine rich repeat and pyrin containing protein 3) inflammasome. NLRP3 activation leads to caspase-1 a
Externí odkaz:
https://doaj.org/article/3061d64f6a8249cd8c02b6054d7cf96f
Autor:
Valentin Derangère, Anne Laure Le Page, David Rageot, Elise Ballot, Caroline Truntzer, François Ghiringhelli, Frédéric Bibeau, Alis Ilie
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports
Scientific Reports
Histological stratification in metastatic non-small cell lung cancer (NSCLC) is essential to properly guide therapy. Morphological evaluation remains the basis for subtyping and is completed by additional immunohistochemistry (IHC) labelling to confi
Autor:
Valentin Derangère, Julie Lecuelle, Come Lepage, Oumaima Aoulad-Ben Salem, Ben M. Allatessem, Alis Ilie, Olivier Bouché, Jean-Marc Phelip, Mathieu Baconnier, Denis Pezet, Virginie Sebbagh, Eric Terrebonne, Gauthier Bouard, Valérie Jooste, Anne-Marie Bouvier, Chloé Molimard, Franck Monnien, Daniel Gonzalez, Karine Le Malicot, David Rageot, Caroline Truntzer, Fréderic Bibeau, Francois Ghiringhelli
Publikováno v:
European journal of cancer (Oxford, England : 1990). 172
Stratification of colon cancer (CC) of patients with stage II and III for risk of relapse is still needed especially to drive adjuvant therapy administration. Our study evaluates the prognostic performance of two known biomarkers, CDX2 and CD3, stand