Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Alireza Khoshbin Khoshnazar"'
Valproic acid, a histone deacetylase inhibitor, enhances radiosensitivity in breast cancer cell line
Autor:
Ahmad Yarmohamadi, Jahanbakhsh Asadi, Roghaye Gharaei, Mostafa Mir, Alireza Khoshbin Khoshnazar
Publikováno v:
Journal of Radiation and Cancer Research, Vol 9, Iss 2, Pp 86-92 (2018)
Purpose: Valproic acid (VPA) is used mainly for the treatment of epilepsy and other seizure disorders, however, it is known to be one of histone deacetylase (HDAC) inhibitors. HDACIs have represented roles in radiation-sensitizing of cancer cells. Th
Externí odkaz:
https://doaj.org/article/4b329b7706dc4c6cae985236e7f68ae3
Publikováno v:
Medical Laboratory Journal, Vol 11, Iss 2, Pp 11-15 (2017)
ABSTRACT Background and Objectives: Exposure to ionizing radiation in modern societies is inevitable and can cause a variety of adverse health effects such as cancer and birth defects. Therefore, a reliable, repeatable and sensitive method is requir
Externí odkaz:
https://doaj.org/article/478af692633e4bcc85c633e37f2512c2
Autor:
Ahmad yarmohamadi, Jahanbakhsh Asadi, Alireza Khoshbin khoshnazar, Mohammad Mostakhdem Hashemi
Publikováno v:
Iranian Journal of Medical Physics, Vol 13, Iss 4, Pp 289-295 (2016)
Introduction H istone deacetylase inhibitors (HDIs), as radiation sensitizing agents, are considered as a novel class of anti-cancer factors, which are studied in various tumor cell-lines. Valproic acid (VPA) is an HDI, which is effectively used in t
Externí odkaz:
https://doaj.org/article/560da461d70747898a53144157b2e079
Autor:
Seyed Mostafa Mir, Esmaeil Samadian, Sahar Alijanpour, Alireza Khoshbin Khoshnazar, Hamid Haghighatfard, Seyed Hossein Sadeghi
Publikováno v:
Medical Laboratory Journal, Vol 10, Iss 5, Pp 22-26 (2016)
Background and Objective: The cell division cycle 25 (CDC25)is a familyof highly conserved dual-specificity phosphatases that activate cyclin-dependent kinase complexes. These complexes are the main cell cycle regulators. Mammalian cells ,exposure to
Externí odkaz:
https://doaj.org/article/5a28423dd49a41b2ac940cc5f01b50c2
Publikováno v:
Iranian Journal of Medical Physics, Vol 12, Iss 1, Pp 14-21 (2015)
Introduction DNA damage is among the main consequences of radiation. Of many different classes of DNA damage, double-strand breaks are the most deleterious. Development of a sensitive biodosimetry method, which utilizes a detection material with a si
Externí odkaz:
https://doaj.org/article/73905f454d954ea1976f8c300b0261dc
Publikováno v:
Annals of Medicine & Surgery.
Publikováno v:
Breast Cancer: Targets and Therapy. 11:303-307
Background Accelerated partial breast irradiation (APBI) is a method in which just bed of lumpectomy with a margin of 1-2 cm is irradiated. Regarding advantages of APBI to whole-brain radiation therapy (WBRT) and limitations for performing other tech
Publikováno v:
Physica Scripta. 97:105304
The photoneutron spectra and ambient dose equivalent were determined in a radiotherapy room with a 15 MV linear accelerator using Monte Carlo simulation. A modified simple geometry of the accelerator’s head was modeled by different simulations. The
Valproic acid, a histone deacetylase inhibitor, enhances radiosensitivity in breast cancer cell line
Autor:
Roghaye Gharaei, Ahmad Yarmohamadi, Jahanbakhsh Asadi, Mostafa Mir, Alireza Khoshbin Khoshnazar
Publikováno v:
Journal of Radiation and Cancer Research, Vol 9, Iss 2, Pp 86-92 (2018)
Purpose: Valproic acid (VPA) is used mainly for the treatment of epilepsy and other seizure disorders, however, it is known to be one of histone deacetylase (HDAC) inhibitors. HDACIs have represented roles in radiation-sensitizing of cancer cells. Th
Publikováno v:
Radiation Physics and Chemistry. 188:109604