Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Alireza Khodadadi"'
Autor:
Hongsu Wang, Komal Kumar Bollepogu Raja, Kelvin Yeung, Carolyn A. Morrison, Antonia Terrizzano, Alireza Khodadadi-Jamayran, Phoenix Chen, Ashley Jordan, Cornelia Fritsch, Simon G. Sprecher, Graeme Mardon, Jessica E. Treisman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The integration of extrinsic signaling with cell-intrinsic transcription factors can direct progenitor cells to differentiate into distinct cell fates. In the developing Drosophila eye, differentiation of photoreceptors R1–R7 requires EGFR
Externí odkaz:
https://doaj.org/article/45d77916a65c4e9383934a0a35b2215b
Autor:
Samantha K. Smith, Paul W. Frazel, Alireza Khodadadi-Jamayran, Paul Zappile, Christian Marier, Mariam Okhovat, Stuart Brown, Michael A. Long, Adriana Heguy, Steven M. Phelps
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Developing genomic resources for a diverse range of species is an important step towards understanding the mechanisms underlying complex traits. Specifically, organisms that exhibit unique and accessible phenotypes-of-interest all
Externí odkaz:
https://doaj.org/article/798eb7a09956465eb3041f88f28ffb5e
Autor:
Niklas Ravn-Boess, Nainita Roy, Takamitsu Hattori, Devin Bready, Hayley Donaldson, Christopher Lawson, Cathryn Lapierre, Aryeh Korman, Tori Rodrick, Enze Liu, Joshua D. Frenster, Gabriele Stephan, Jordan Wilcox, Alexis D. Corrado, Julia Cai, Rebecca Ronnen, Shuai Wang, Sara Haddock, Jonathan Sabio Ortiz, Orin Mishkit, Alireza Khodadadi-Jamayran, Aris Tsirigos, David Fenyö, David Zagzag, Julia Drube, Carsten Hoffmann, Fabiana Perna, Drew R. Jones, Richard Possemato, Akiko Koide, Shohei Koide, Christopher Y. Park, Dimitris G. Placantonakis
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113374- (2023)
Summary: Glioblastoma (GBM) is the most common and aggressive primary brain malignancy. Adhesion G protein-coupled receptors (aGPCRs) have attracted interest for their potential as treatment targets. Here, we show that CD97 (ADGRE5) is the most promi
Externí odkaz:
https://doaj.org/article/e954f101e34e4454841a124bf6a6e405
Publikováno v:
Sahand Communications in Mathematical Analysis, Vol 19, Iss 4, Pp 39-50 (2022)
In this paper, we investigate Godunova type inequality for Sugeno integrals in two cases. At the first case, we suppose that the inner integral is the Riemann integral and the remaining two integrals are of Sugeno type. At the second case, all the in
Externí odkaz:
https://doaj.org/article/43be9dee8534493898179521f121d978
Autor:
Leena Ali Ibrahim, Brie Wamsley, Norah Alghamdi, Nusrath Yusuf, Elaine Sevier, Ariel Hairston, Mia Sherer, Xavier Hubert Jaglin, Qing Xu, Lihua Guo, Alireza Khodadadi-Jamayran, Emilia Favuzzi, Yuan Yuan, Jordane Dimidschstein, Robert B Darnell, Gordon Fishell
Publikováno v:
eLife, Vol 12 (2023)
Somatostatin interneurons are the earliest born population of cortical inhibitory cells. They are crucial to support normal brain development and function; however, the mechanisms underlying their integration into nascent cortical circuitry are not w
Externí odkaz:
https://doaj.org/article/7028adc05aec4318b63b020ee9fdf06a
Autor:
Elena Spina, Julia Simundza, Angela Incassati, Anupama Chandramouli, Matthias C. Kugler, Ziyan Lin, Alireza Khodadadi-Jamayran, Christine J. Watson, Pamela Cowin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Gpr125 has emerged as a specific marker of mammary stem cells and basal progenitors. Here they show that Gpr125 cells congregate at ductal tips during morphogenesis and amass at tumor margins, and that high Gpr125 predicts early tumor onset and poor
Externí odkaz:
https://doaj.org/article/ce7bc99fa1f146eabcbf6f7745f6c135
Autor:
Krystal L Ching, Maren de Vries, Juan Gago, Kristen Dancel-Manning, Joseph Sall, William J Rice, Clea Barnett, Alireza Khodadadi-Jamayran, Aristotelis Tsirigos, Feng-Xia Liang, Lorna E Thorpe, Bo Shopsin, Leopoldo N Segal, Meike Dittmann, Victor J Torres, Ken Cadwell
Publikováno v:
PLoS Biology, Vol 20, Iss 9, p e3001754 (2022)
Extracellular vesicles of endosomal origin, exosomes, mediate intercellular communication by transporting substrates with a variety of functions related to tissue homeostasis and disease. Their diagnostic and therapeutic potential has been recognized
Externí odkaz:
https://doaj.org/article/cdfa812871bd4a9099e6eaf53a65cffd
Autor:
Jenny R. Diaz, Mitchell Martá-Ariza, Alireza Khodadadi-Jamayran, Adriana Heguy, Aristotelis Tsirigos, Joanna E. Pankiewicz, Patrick M. Sullivan, Martin J. Sadowski
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
The APOE gene is diversified by three alleles ε2, ε3, and ε4 encoding corresponding apolipoprotein (apo) E isoforms. Possession of the ε4 allele is signified by increased risks of age-related cognitive decline, Alzheimer’s disease (AD), and the
Externí odkaz:
https://doaj.org/article/310c629614a240ba91a7f8f03701f288
Autor:
Sascha Kahlfuss, Ulrike Kaufmann, Axel R Concepcion, Lucile Noyer, Dimitrius Raphael, Martin Vaeth, Jun Yang, Priya Pancholi, Mate Maus, James Muller, Lina Kozhaya, Alireza Khodadadi‐Jamayran, Zhengxi Sun, Patrick Shaw, Derya Unutmaz, Peter B Stathopulos, Cori Feist, Scott B Cameron, Stuart E Turvey, Stefan Feske
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 8, Pp 1-25 (2020)
Abstract Immunity to fungal infections is mediated by cells of the innate and adaptive immune system including Th17 cells. Ca2+ influx in immune cells is regulated by stromal interaction molecule 1 (STIM1) and its activation of the Ca2+ channel ORAI1
Externí odkaz:
https://doaj.org/article/5dea67d69b0a4240ad6b7dfd0ac39c79
Autor:
Scott C. Thomas, Fangxi Xu, Smruti Pushalkar, Ziyan Lin, Nirali Thakor, Mridula Vardhan, Zia Flaminio, Alireza Khodadadi-Jamayran, Rebeca Vasconcelos, Adenike Akapo, Erica Queiroz, Maria Bederoff, Malvin N. Janal, Yuqi Guo, Deanna Aguallo, Terry Gordon, Patricia M. Corby, Angela R. Kamer, Xin Li, Deepak Saxena
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Electronic cigarettes (e-cigs) have become prevalent as an alternative to conventional cigarette smoking, particularly in youth. E-cig aerosols contain unique chemicals which alter the oral microbiome and promote dysbiosis in ways we are jus
Externí odkaz:
https://doaj.org/article/fafdf42b89344894b25171a925472a4d