Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Alireza Khanteymoori"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract In this study, we introduce StructmRNA, a new BERT-based model that was designed for the detailed analysis of mRNA sequences and structures. The success of DNABERT in understanding the intricate language of non-coding DNA with bidirectional
Externí odkaz:
https://doaj.org/article/9a7ea637f50c4888a08f4fe99a526154
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 4, Pp 102370- (2024)
Prime editors are CRISPR-based genome engineering tools with significant potential for rectifying patient mutations. However, their usage requires experimental optimization of the prime editing guide RNA (PegRNA) to achieve high editing efficiency. T
Externí odkaz:
https://doaj.org/article/be68ede751734db5b4fc4670d92ad429
Autor:
Julian Hirt, Alireza Khanteymoori, Marc Hohenhaus, Marcel A. Kopp, David W. Howells, Jan M. Schwab, Ralf Watzlawick
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Recovery after spinal cord injury (SCI) may be propagated by plasticity-enhancing treatments. The myelin-associated nerve outgrowth inhibitor Nogo-A (Reticulon 4, RTN4) pathway has been shown to restrict neuroaxonal plasticity in experimenta
Externí odkaz:
https://doaj.org/article/e499425624b04757b2f9f90c406e4764
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract SARS-CoV-2 pandemic first emerged in late 2019 in China. It has since infected more than 298 million individuals and caused over 5 million deaths globally. The identification of essential proteins in a protein–protein interaction network (
Externí odkaz:
https://doaj.org/article/febd4e829deb45378ff986db99d78161
Publikováno v:
Frontiers in Bioinformatics, Vol 2 (2023)
Clustered regularly interspaced short palindromic repeats (CRISPR)-based gene editing has been widely used in various cell types and organisms. To make genome editing with Clustered regularly interspaced short palindromic repeats far more precise and
Externí odkaz:
https://doaj.org/article/bced320b29d64348b2830ea6f458b8ca
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-15 (2020)
Abstract Background Single individual haplotype problem refers to reconstructing haplotypes of an individual based on several input fragments sequenced from a specified chromosome. Solving this problem is an important task in computational biology an
Externí odkaz:
https://doaj.org/article/a4539965fbfb47eeb6371094bc3d0111
Autor:
Anna-Lena Lamprecht, Magnus Palmblad, Jon Ison, Veit Schwämmle, Mohammad Sadnan Al Manir, Ilkay Altintas, Christopher J. O. Baker, Ammar Ben Hadj Amor, Salvador Capella-Gutierrez, Paulos Charonyktakis, Michael R. Crusoe, Yolanda Gil, Carole Goble, Timothy J. Griffin, Paul Groth, Hans Ienasescu, Pratik Jagtap, Matúš Kalaš, Vedran Kasalica, Alireza Khanteymoori, Tobias Kuhn, Hailiang Mei, Hervé Ménager, Steffen Möller, Robin A. Richardson, Vincent Robert, Stian Soiland-Reyes, Robert Stevens, Szoke Szaniszlo, Suzan Verberne, Aswin Verhoeven, Katherine Wolstencroft
Publikováno v:
F1000Research, Vol 10 (2021)
Scientific data analyses often combine several computational tools in automated pipelines, or workflows. Thousands of such workflows have been used in the life sciences, though their composition has remained a cumbersome manual process due to a lack
Externí odkaz:
https://doaj.org/article/e9b280176ab24646b8b7d023b327e100
Autor:
Qiang Gu, Anup Kumar, Simon Bray, Allison Creason, Alireza Khanteymoori, Vahid Jalili, Björn Grüning, Jeremy Goecks
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 6, p e1009014 (2021)
Supervised machine learning is an essential but difficult to use approach in biomedical data analysis. The Galaxy-ML toolkit (https://galaxyproject.org/community/machine-learning/) makes supervised machine learning more accessible to biomedical scien
Externí odkaz:
https://doaj.org/article/cc0c9acee42140dc8b0a5f096e5da22d
Publikováno v:
Informatics in Medicine Unlocked, Vol 25, Iss , Pp 100646- (2021)
Studying human genetic evolution has attracted considerable attention. Haplotypes determination provides key information about human genetics, and facilitates understanding probable causal relations between traits and diseases. In general, experiment
Externí odkaz:
https://doaj.org/article/103f6f36493f43439b2c325991e08ae8
Publikováno v:
Informatics in Medicine Unlocked, Vol 27, Iss , Pp 100773- (2021)
The development of computational methods to predict gene regulatory networks (GRNs) from gene expression data is a challenging task. Many machine learning methods have been developed, including supervised, unsupervised, and semi-supervised to infer g
Externí odkaz:
https://doaj.org/article/57df77b729fa4622b918d2d9efaeaece