Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Alireza Heravi Moussavi"'
Autor:
Andrew McPherson, Fereydoun Hormozdiari, Abdalnasser Zayed, Ryan Giuliany, Gavin Ha, Mark G F Sun, Malachi Griffith, Alireza Heravi Moussavi, Janine Senz, Nataliya Melnyk, Marina Pacheco, Marco A Marra, Martin Hirst, Torsten O Nielsen, S Cenk Sahinalp, David Huntsman, Sohrab P Shah
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 5, p e1001138 (2011)
Gene fusions created by somatic genomic rearrangements are known to play an important role in the onset and development of some cancers, such as lymphomas and sarcomas. RNA-Seq (whole transcriptome shotgun sequencing) is proving to be a useful tool f
Externí odkaz:
https://doaj.org/article/c9b389b739544cc28b879c2f050782a1
Autor:
Mafalda Santos, Marta Ferreira, Patrícia Oliveira, Nuno Mendes, Ana André, André F. Vieira, Joana B. Nunes, Joana Carvalho, Sara Rocha, Mafalda Azevedo, Daniel Ferreira, Inês Reis, João Vinagre, Joana Paredes, Alireza Heravi-Moussavi, Jorge Lima, Valdemar Máximo, Angela Burleigh, Calvin Roskelley, Fátima Carneiro, David Huntsman, Carla Oliveira
Publikováno v:
Biology, Vol 11, Iss 7, p 1046 (2022)
Transitions between epithelial and mesenchymal cellular states (EMT/MET) contribute to cancer progression. We hypothesize that EMT followed by MET promotes cell population heterogeneity, favouring tumour growth. We developed an EMT model by on and of
Externí odkaz:
https://doaj.org/article/7302372388394956b9b27c7225a965ca
Autor:
Edith Schneider, Anna Staffas, Linda Röhner, Erik D. Malmberg, Arghavan Ashouri, Kathrin Krowiorz, Nicole Pochert, Christina Miller, Stella Yuan Wei, Laleh Arabanian, Christian Buske, Hartmut Döhner, Lars Bullinger, Linda Fogelstrand, Michael Heuser, Konstanze Döhner, Ping Xiang, Jens Ruschmann, Oleh I. Petriv, Alireza Heravi-Moussavi, Carl L. Hansen, Martin Hirst, R. Keith Humphries, Arefeh Rouhi, Lars Palmqvist, Florian Kuchenbauer
Publikováno v:
Haematologica, Vol 103, Iss 2 (2018)
Micro-ribonucleic acid-155 (miR-155) is one of the first described oncogenic miRNAs. Although multiple direct targets of miR-155 have been identified, it is not clear how it contributes to the pathogenesis of acute myeloid leukemia. We found miR-155
Externí odkaz:
https://doaj.org/article/87401d72d1534be9b48a6f1e53390dbc
Autor:
Narjes Forouzanfar, Ancha Baranova, Saman Milanizadeh, Alireza Heravi-Moussavi, Amir Jebelli, Mohammad Reza Abbaszadegan
Publikováno v:
Tumor Biology, Vol 39 (2017)
Esophageal squamous cell carcinoma is one of the deadliest of all the cancers. Its metastatic properties portend poor prognosis and high rate of recurrence. A more advanced method to identify new molecular biomarkers predicting disease prognosis can
Externí odkaz:
https://doaj.org/article/d2f312ecc8834922983fcebae0c0493d
Autor:
Marta Ferreira, Mafalda Azevedo, David G. Huntsman, Joana Carvalho, Angela Burleigh, Alireza Heravi-Moussavi, Joana B. Nunes, Patrícia Oliveira, Daniel Ferreira, Ana André, Joana Paredes, André Filipe Vieira, Inês Leal Reis, Maria de Fátima Carneiro, Valdemar Máximo, João Vinagre, Sara Rocha, Mafalda Santos, Carla Oliveira, Nuno Mendes, Jorge Lima, Calvin D. Roskelley
Publikováno v:
Biology; Volume 11; Issue 7; Pages: 1046
Transitions between epithelial and mesenchymal cellular states (EMT/MET) contribute to cancer progression. We hypothesize that EMT followed by MET promotes cell population heterogeneity favouring tumour growth. We developed an EMT model by on/off exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de34328f3b592e90d41e20644d372533
https://doi.org/10.1101/2021.11.02.466914
https://doi.org/10.1101/2021.11.02.466914
Autor:
Florian Kuchenbauer, Meena Kanduri, Lars Palmqvist, Reinhild Rösler, Christoph Ruess, Nadine Sperb, Christina Miller, Hartmut Döhner, Nicole Pochert, Erik Delsing Malmberg, Martin Hirst, Anna Staffas, Pradeep Kumar Kopparapu, Alireza Heravi-Moussavi, Alireza Lorzadeh, Ping Xiang, R. Keith Humphries, Sarah Grasedieck, Erik Larsson, Sebastian Wiese, Arghavan Ashouri, Liam MacPhee, Konstanze Döhner, Leo Escano, Linda Fogelstrand, Sebastian Iben, Edith Schneider, Kathrin Krowiorz, Arefeh Rouhi
Publikováno v:
Leukemia. 34:1253-1265
MicroRNAs (miRNAs) are commonly deregulated in acute myeloid leukemia (AML), affecting critical genes not only through direct targeting, but also through modulation of downstream effectors. Homeobox (Hox) genes balance self-renewal, proliferation, ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d076b36c05970c320be90295fd04c8e0
https://doi.org/10.1038/s41375-019-0651-1
https://doi.org/10.1038/s41375-019-0651-1
Autor:
Cecile L. Maire, Stephanie Cho, Marco A. Marra, Annaick Carles, Raman P. Nagarajan, Dorothy Cheung, Nada Jabado, Irene Li, Chibo Hong, Keith L. Ligon, Tina Wong, Steven J.M. Jones, Baljit Kamoh, Angela Tam, Andrew J. Mungall, Richard D. Moore, Ting Wang, Luolan Li, Misha Bilenky, Joseph F. Costello, Martin Hirst, Claudia L. Kleinman, Alireza Heravi-Moussavi
Publikováno v:
Epigenomics, vol 12, iss 12
Epigenomics
Epigenomics
Aim: To provide a comprehensive understanding of gene regulatory networks in the developing human brain and a foundation for interpreting pathogenic deregulation. Materials & methods: We generated reference epigenomes and transcriptomes of dissected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6cd0065f215cb6c29c3f09f89ceb11
https://escholarship.org/uc/item/9x42z396
https://escholarship.org/uc/item/9x42z396
Autor:
Mahdieh Dayyani, Maryam Yassi, Alireza Heravi-Moussavi, Mohammad Amin Kerachian, Ehsan Shams Davodly, Afsaneh Mojtabanezhad Shariatpanahi, Mehdi Heidari, Mohammad Hossein Moattar
Publikováno v:
Genomics. 110:366-374
DNA methylation is an important epigenetic modification involved in many biological processes and diseases. Computational analysis of differentially methylated regions (DMRs) could explore the underlying reasons of methylation. DMRFusion is presented
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e082cf6ccbbbb1ffd079c2b4e7866374
https://doi.org/10.1016/j.ygeno.2017.12.006
https://doi.org/10.1016/j.ygeno.2017.12.006
Autor:
Fumio Takei, Avinash Bhandoola, Arundhoti Das, Alireza Heravi-Moussavi, Lisa Wei, Maryam Ghaedi, Zi Yi Shen, Itziar Martinez-Gonzalez, Mona Orangi, Xiaoxiao Lu, Marco A. Marra
Publikováno v:
The Journal of Experimental Medicine
Ghaedi et al. identify IL-18R+IL-33R− ILC progenitors, which differentiate into multiple ILC lineages, in the lung of neonatal and adult RORα lineage tracer mice. ILC2s in neonatal mouse lungs are divided into distinct cytokine and amphiregulin-pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086f877d247dde1767685664379bbcc9
https://doi.org/10.1084/jem.20182293
https://doi.org/10.1084/jem.20182293
Autor:
Maryam Ghaedi, Mona Orangi, Itziar Martinez-Gonzalez, Lisa Wei, Xiaoxiao Lu, Arundhoti Das, Alireza Heravi-Moussavi, Marco A. Marra, Fumio Takei
Publikováno v:
Journal of Experimental Medicine.
Lung group 2 innate lymphoid cells (ILC2s) drive allergic inflammation and promote tissue repair. ILC2 development is dependent on the transcription factor retinoic acid receptor–related orphan receptor (RORα), which is also expressed in common IL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a54a8d218919307d61af7eccb19eedc
https://doi.org/10.1084/20182293
https://doi.org/10.1084/20182293