Precision cut intestinal slices, a novel model of acute food allergic reactions

Autor: Lisa Hung, Alper Celik, Xiaojun Yin, Kai Yu, Alireza Berenjy, Akash Kothari, Helena Obernolte, Julia E. M. Upton, Katrine Lindholm Bøgh, Gino R. Somers, Iram Siddiqui, Martin Grealish, Fayez A. Quereshy, Katherina Sewald, Priscilla P. L. Chiu, Thomas Eiwegger

Publikováno v: Hung, L, Celik, A, Yin, X, Yu, K, Berenjy, A, Kothari, A, Obernolte, H, Upton, J E M, Lindholm Bøgh, K, Somers, G R, Siddiqui, I, Grealish, M, Quereshy, F A, Sewald, K, Chiu, P P L & Eiwegger, T 2023, ' Precision cut intestinal slices, a novel model of acute food allergic reactions ', Allergy, vol. 78, no. 2, pp. 500-511 . https://doi.org/10.1111/all.15579

Background: Food allergy affects up to 8% of the pediatric population. Despite ongoing efforts, treatment options remain limited. Novel models of food allergy are needed to study response patterns downstream of IgE-crosslinking and evaluate drugs mod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f039022cf3c19f43574387d5f4d34871
https://pubmed.ncbi.nlm.nih.gov/36377289

Basophil activation test shows high accuracy in the diagnosis of peanut and tree nut allergy: The Markers of Nut Allergy Study

Autor: Zsolt Szépfalusi, Vy Hong-Diep Kim, Arun K. Ramani, Thomas Eiwegger, Marta Ponce, Mindy Tsai, Delvin So, Lisa Hung, Jennifer A. Hoang, Alper Celik, David Hummel, Heimo Breiteneder, Stephen J. Galli, Xiaojun Yin, Sharon Chinthrajah, Lucy Duan, Chiara Palladino, Kaori Mukai, Alireza Berenjy, Julia Upton, Kari C. Nadeau, Mara Alexanian-Farr, Jean-Soo Lee, Samantha Wong, Adelle Atkinson, Klara Schmidthaler, Maria Asper, Christina M Ditlof, Ahuva Magder

Publikováno v: Allergy

Background Peanut and tree nut allergies are the most important causes of anaphylaxis. Co-reactivity to more than one nut is frequent, and co-sensitization in the absence of clinical data is often obtained. Confirmatory oral food challenges (OFCs) ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afcceff041c66576d2eaae6a840873e6
https://pubmed.ncbi.nlm.nih.gov/33300157