Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Alireza, Morovat"'
Autor:
Reagan M. Mogire, Alireza Morovat, John Muthii Muriuki, Alexander J. Mentzer, Emily L. Webb, Wandia Kimita, Francis M. Ndungu, Alex W. Macharia, Clare L. Cutland, Sodiomon B. Sirima, Amidou Diarra, Alfred B. Tiono, Swaib A. Lule, Shabir A. Madhi, Manjinder S. Sandhu, Andrew M. Prentice, Philip Bejon, John M. Pettifor, Alison M. Elliott, Adebowale Adeyemo, Thomas N. Williams, Sarah H. Atkinson
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Children living in sub-Saharan Africa have a high burden of rickets and infectious diseases, conditions that are linked to vitamin D deficiency. However, data on the vitamin D status of young African children and its environmental
Externí odkaz:
https://doaj.org/article/af36fc5b4df647808f587d75066738fb
Autor:
John Muthii Muriuki, Alexander J. Mentzer, Emily L. Webb, Alireza Morovat, Wandia Kimita, Francis M. Ndungu, Alex W. Macharia, Rosie J. Crane, James A. Berkley, Swaib A. Lule, Clare Cutland, Sodiomon B. Sirima, Amidou Diarra, Alfred B. Tiono, Philip Bejon, Shabir A. Madhi, Adrian V. S. Hill, Andrew M. Prentice, Parminder S. Suchdev, Alison M. Elliott, Thomas N. Williams, Sarah H. Atkinson
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background Iron deficiency (ID) is a major public health burden in African children and accurate prevalence estimates are important for effective nutritional interventions. However, ID may be incorrectly estimated in Africa because most meas
Externí odkaz:
https://doaj.org/article/c4b8577e01b24a9aa3d0e11b1e8c3f55
Autor:
Bhavika Parmanand, Michael Watson, Karen J. Boland, Narayan Ramamurthy, Victoria Wharton, Alireza Morovat, Elizabeth K. Lund, Jane Collier, Gwenaelle Le Gall, Lee Kellingray, Susan Fairweather-Tait, Jeremy F. Cobbold, Arjan Narbad, John D. Ryan
Publikováno v:
JHEP Reports, Vol 2, Iss 6, Pp 100154- (2020)
Background & Aims: Iron reduction by venesection has been the cornerstone of treatment for haemochromatosis for decades, and its reported health benefits are many. Repeated phlebotomy can lead to a compensatory increase in intestinal iron absorption,
Externí odkaz:
https://doaj.org/article/aaf38f7fec6b4094b6800faa2dd46e90
Autor:
Karl J Morten, Michelle Potter, Luned Badder, Pamela Sivathondan, Rebecca Dragovic, Abigale Neumann, James Gavin, Roshan Shrestha, Svetlana Reilly, Kanchan Phadwal, Tiffany A. Lodge, Angela Borzychowski, Sharon Cookson, Corey Mitchell, Alireza Morovat, Anna Katharina Simon, Johanna Uusimaa, James Hynes, Joanna Poulton
Publikováno v:
Wellcome Open Research, Vol 2 (2019)
Background: Mitochondrial diabetes is primarily caused by β-cell failure, a cell type whose unique properties are important in pathogenesis. Methods: By reducing glucose, we induced energetic stress in two rodent β-cell models to assess effects on
Externí odkaz:
https://doaj.org/article/fe13c9ee59e34f6b87ed8a15400ee82f
Autor:
Johnstone Makale, Amidou Diarra, Crystal D Karakochuk, Ruth Mitchell, Robert W. Snow, Francis M. Ndungu, Laura M. Raffield, Kirk A. Rockett, Alexander J. Mentzer, Parminder S. Suchdev, John Muthii Muriuki, Rita Wegmüller, Catherine Kyobutungi, Sodiomon B. Sirima, Thomas N. Williams, Dominic P. Kwiatkowski, Moses Gwamaka, Clare L. Cutland, Seth Adu-Afarwuah, Adrian V. S. Hill, Alison M. Elliott, James P. Wirth, Wandia Kimita, Patrick E. Duffy, Caroline Ngetsa, Manjinder S. Sandhu, Andrew M. Prentice, Christine P. Stewart, Kendra A. Byrd, Michal Fried, Alireza Morovat, Emily L. Webb, Alex Macharia, Timothy J. Green, Alfred B. Tiono, Sarah H. Atkinson, Shabir A. Madhi, Reina Engle-Stone, Philip Bejon, George Davey Smith, Alex Ndjebayi, Solomon K. Musani, Swaib A. Lule, Anthony Etyang
Publikováno v:
Nature medicine
muriuki, J, Mentzer, A J, Mitchell, R E, Webb, E L, Etyang, A O, Kyobutungi, C, Morovat, A, Kimita, W, Ndungu, F M, Macharia, A W, Ngetsa, C, Makale, J, Lule, S A, Musani, S K, Raffield, L M, Cutland, C L, Sirima, S B, Diarra, A, Tiono, A B, Fried, M, Gwamaka, M, Adu-Afarwuah, S & Davey Smith, G 2021, ' Malaria is a cause of iron deficiency in African children ', Nature Medicine, vol. 27, no. 4, pp. 653-658 . https://doi.org/10.1038/s41591-021-01238-4
Nature medicine, vol 27, iss 4
muriuki, J, Mentzer, A J, Mitchell, R E, Webb, E L, Etyang, A O, Kyobutungi, C, Morovat, A, Kimita, W, Ndungu, F M, Macharia, A W, Ngetsa, C, Makale, J, Lule, S A, Musani, S K, Raffield, L M, Cutland, C L, Sirima, S B, Diarra, A, Tiono, A B, Fried, M, Gwamaka, M, Adu-Afarwuah, S & Davey Smith, G 2021, ' Malaria is a cause of iron deficiency in African children ', Nature Medicine, vol. 27, no. 4, pp. 653-658 . https://doi.org/10.1038/s41591-021-01238-4
Nature medicine, vol 27, iss 4
Malaria and iron deficiency (ID) are common and interrelated public health problems in African children. Observational data suggest that interrupting malaria transmission reduces the prevalence of ID1. To test the hypothesis that malaria might cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96de8a1482060483305a4bdc27e6a8a7
http://europepmc.org/articles/PMC7610676
http://europepmc.org/articles/PMC7610676
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165462 (2016)
Despite differences in the phamacokinetics of 25-hydroxycholecalciferol (25(OH)D3) and 25-hydroxyergocalciferol (25(OH)D2) in man, the effects of these and their 1α-hydroxylated forms (1,25(OH)2D3 and 1,25(OH)2D2) on cellular activity of vitamin D-r
Externí odkaz:
https://doaj.org/article/457c3a54886f4d8a8b4ee1c8092d81cc
Autor:
Reagan M. Mogire, John Muthii Muriuki, Alireza Morovat, Alexander J. Mentzer, Emily L. Webb, Wandia Kimita, Francis M. Ndungu, Alex W. Macharia, Clare L. Cutland, Sodiomon B. Sirima, Amidou Diarra, Alfred B. Tiono, Swaib A. Lule, Shabir A. Madhi, Andrew M. Prentice, Philip Bejon, John M. Pettifor, Alison M. Elliott, Adebowale Adeyemo, Thomas N. Williams, Sarah H. Atkinson
Publikováno v:
Nutrients; Volume 14; Issue 7; Pages: 1372
NUTRIENTS
NUTRIENTS
Vitamin D regulates the master iron hormone hepcidin, and iron in turn alters vitamin D metabolism. Although vitamin D and iron deficiency are highly prevalent globally, little is known about their interactions in Africa. To evaluate associations bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47d2f577aab8b665eb00829b8f5295d1
https://pubmed.ncbi.nlm.nih.gov/35405984
https://pubmed.ncbi.nlm.nih.gov/35405984
Autor:
Philip Bejon, John Muthii Muriuki, Alfred B. Tiono, Adebowale Adeyemo, Swaib A. Lule, Francis M. Ndungu, Alexander J. Mentzer, Alexander Macharia, Alireza Morovat, Andrew M. Prentice, Shabir A. Madhi, Clare L. Cutland, Thomas N. Williams, Alison M. Elliott, John M. Pettifor, Sarah H. Atkinson, Emily L. Webb, Reagan M. Mogire, S. B. BSirima, Amidou Diarra, Wandia Kimita
Background Nutritional deficiencies, including vitamin D and iron deficiency, are prevalent among children living in sub-Saharan Africa. Vitamin D inhibits the transcription of the iron hormone hepcidin thus permitting efficient iron absorption, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23c27b63c77991a7dd66312bc5b4a994
https://doi.org/10.1101/2021.07.14.21260499
https://doi.org/10.1101/2021.07.14.21260499
Autor:
Yoav Ben-Shlomo, Alireza Morovat, Fahd Baig, Michele T.M. Hu, Michael A Lawton, Samuel Evetts, Greg Toulson
Publikováno v:
Movement Disorders
Lawton, M A, Baig, F, Toulson, G, Morovat, A, Evetts, S G, Ben-Shlomo, Y & Hu, M 2019, ' Blood biomarkers with Parkinson’s disease clusters and prognosis: the Oxford Discovery cohort ', Movement Disorders . https://doi.org/10.1002/mds.27888
Lawton, M A, Baig, F, Toulson, G, Morovat, A, Evetts, S G, Ben-Shlomo, Y & Hu, M 2019, ' Blood biomarkers with Parkinson’s disease clusters and prognosis: the Oxford Discovery cohort ', Movement Disorders . https://doi.org/10.1002/mds.27888
BackgroundPredicting prognosis in Parkinson's disease (PD) has important implications for individual prognostication and clinical trials design and targeting novel treatments. Blood biomarkers could help in this endeavor.MethodsWe identified 4 blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64fbde4f3e25228a53f1ad81b81b39c3
http://europepmc.org/articles/PMC7028059
http://europepmc.org/articles/PMC7028059
Autor:
David I. Thurnham, Chandresh Ladva, Ben Lopman, Anne M Williams, Alireza Morovat, Sherry A. Tanumihardjo, Ralph D. Whitehead, Andrew E. Armitage, Parminder S. Suchdev, Juan S. Leon, Katherine Wray, Rafael Flores-Ayala, Vin Tangpricha, Lindsay H. Allen, Sant-Rayn Pasricha, Setti Shahab-Ferdows
Publikováno v:
The American Journal of Clinical Nutrition
Background To accurately assess micronutrient status, it is necessary to characterize the effects of inflammation and the acute-phase response on nutrient biomarkers. Objective Within a norovirus human challenge study, we aimed to model the inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65baa8628bd34e377cff51ebe669a071
http://europepmc.org/articles/PMC6885472
http://europepmc.org/articles/PMC6885472