Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Aliosha I. Figueroa‐Valdés"'
Autor:
Dario Donoso‐Meneses, Aliosha I. Figueroa‐Valdés, Nicolás Georges, Hugo E. Tobar, Francisca Alcayaga‐Miranda
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 1, Pp n/a-n/a (2023)
Abstract Currently, small extracellular vesicles (sEV) as a nanoscale drug delivery system, are undergoing biotechnological scaling and clinical validation. Nonetheless, preclinical pharmacokinetic studies revealed that sEV are predominantly uptaken
Externí odkaz:
https://doaj.org/article/c9aea6a07a714690a7058ad6fb1b0789
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 716 (2023)
Small extracellular vesicles (sEVs) have burst into biomedicine as a natural therapeutic alternative for different diseases. Considered nanocarriers of biological origin, various studies have demonstrated the feasibility of their systemic administrat
Externí odkaz:
https://doaj.org/article/bb541c99db6a4e53992f7afdfc45aa93
Autor:
Aliosha I. Figueroa-Valdés, Catalina de la Fuente, Yessia Hidalgo, Ana María Vega-Letter, Rafael Tapia-Limonchi, Maroun Khoury, Francisca Alcayaga-Miranda
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Cell therapy is witnessing a notable shift toward cell-free treatments based on paracrine factors, in particular, towards small extracellular vesicles (sEV), that mimic the functional effect of the parental cells. While numerous sEV-based application
Externí odkaz:
https://doaj.org/article/0e67b4a08f6745e999d5b9ccf4f11a14
Autor:
Gabriela Zavala, María-Paz Ramos, Aliosha I. Figueroa-Valdés, Pablo Cisternas, Ursula Wyneken, Macarena Hernández, Pauline Toa, Brian Salmons, John Dangerfield, Walter H. Gunzburg, Maroun Khoury
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The clinical benefit of therapies using Mesenchymal Stem Cells (MSCs) is attributable to their pleiotropic effect over cells and tissues, mainly through their secretome. This paracrine effect is mediated by secreted growth factors and extracellular v
Externí odkaz:
https://doaj.org/article/a8bac53d341549bd929258b00f83f395
Autor:
Dario Donoso‐Meneses, Aliosha I. Figueroa‐Valdés, Nicolás Georges, Hugo E. Tobar, Francisca Alcayaga‐Miranda
Publikováno v:
Bioengineering & Translational Medicine. 8
Autor:
null Dario Donoso Meneses, null Aliosha I. Figueroa‐Valdés, null Nicolás Georges, null Hugo E. Tobar, null Francisca Alcayaga‐Miranda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0299785b3b45d99b0631878c8ebc7912
https://doi.org/10.1002/btm2.10349/v2/response1
https://doi.org/10.1002/btm2.10349/v2/response1
Autor:
Maroun Khoury, Leonie Rosenberger, María Ignacia Ortúzar, Francisca Alcayaga-Miranda, Fernando Ezquer, Fernando Lillo-Vera, Jimena Cuenca, Marcelo Ezquer, Paulina L. Pedraza, Aliosha I. Figueroa-Valdés, Paz Gonzalez
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Recently, exosomes secreted by menstrual mesenchymal stem cells have been identified as inhibitory agents of tumor angiogenesis and modulators of the tumor cell secretome in prostate and breast cancer. However, their direct effect on endothelial cell
Autor:
Noymar Luque-Campos, Rafael Contreras-Lopez, Farida Djouad, Aliosha I. Figueroa-Valdés, Maria Jose Paredes, Maria Jose Torres, Patricia Luz-Crawford, Gautier Tejedor, Carolina Pradenas, Christian Jorgensen, Maroun Khoury, Claudia Altamirano, Roberto Elizondo-Vega, Karina Oyarce, María De Los Ángeles García-Robles, Ana María Vega-Letter
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 34(6)
Hypoxia-inducible factor 1 α (HIF1α), a regulator of metabolic change, is required for the survival and differentiation potential of mesenchymal stem/stromal cells (MSC). Its role in MSC immunoregulatory activity, however, has not been completely e