Zobrazeno 1 - 10
of 226
pro vyhledávání: '"Aling Shen"'
Autor:
Yi Fang, Yulun Wu, Xinran Zhang, Lihui Wei, Liya Liu, Youqin Chen, Daxin Chen, Nanhui Xu, Liujin Cao, Jie Zhu, Mian Chen, Ying Cheng, Thomas J. Sferra, Mengying Yao, Aling Shen, Jun Peng
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Proteasome inhibition emerges as a promising strategy for cancer prevention. PNO1, pivotal for colorectal cancer (CRC) progression, is involved in proteasome assembly in Saccharomyces cerevisiae. Hence, we aimed to explore the role of PNO1 i
Externí odkaz:
https://doaj.org/article/d95710292bd646cf8f0a348cc899a937
Autor:
Liya Liu, Youqin Chen, Yuying Han, Xinran Zhang, Yulun Wu, Jing Lin, Liujing Cao, Meizhu Wu, Huifang Zheng, Yi Fang, Lihui Wei, Thomas J. Sferra, Anjum Jafri, Xiao Ke, Jun Peng, Aling Shen
Publikováno v:
Pharmaceutical Biology, Vol 62, Iss 1, Pp 607-620 (2024)
Context Ulcerative colitis has been clinically treated with Qing Hua Chang Yin (QHCY), a traditional Chinese medicine formula. However, its precise mechanisms in mitigating chronic colitis are largely uncharted.Objective To elucidate the therapeutic
Externí odkaz:
https://doaj.org/article/942f776fc7894a3895d95242b37c2669
Autor:
Liya Liu, Youqin Chen, Sijia Liu, Xinran Zhang, Liujing Cao, Yulun Wu, Yuying Han, Guosheng Lin, Lihui Wei, Yi Fang, Thomas J. Sferra, Anjum Jafri, Huixin Liu, Li Li, Aling Shen
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Pien Tze Huang (PZH), a traditional Chinese medicine formulation, is recognized for its therapeutic effect on colitis and colorectal cancer. However, its protective role and underlying mechanism in colitis-associated colorectal ca
Externí odkaz:
https://doaj.org/article/33150c0839b143969b029647a00fe863
Autor:
Mengying Yao, Ming Wu, Meng Yuan, Meizhu Wu, Aling Shen, Youqin Chen, Dawei Lian, Xiaolong Liu, Jun Peng
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116541- (2024)
Background: Hypertension, a highly prevalent chronic disease, is known to inflict severe damage upon blood vessels. In our previous study, isoliensinine, a kind of bibenzyl isoquinoline alkaloid which isolated from a TCM named Lotus Plumule (Nelumbo
Externí odkaz:
https://doaj.org/article/d476834533de4293ab63af8d52b70583
Autor:
Zhi Guo, Xuan Yang, Meizhu Wu, Aling Shen, Jiapeng Li, Xiuli Zhang, Ying Cheng, Qiurong Xie, Jun Peng
Publikováno v:
Pharmaceutical Biology, Vol 61, Iss 1, Pp 858-867 (2023)
AbstractContext Gastrodin has been used as antihypertension therapy in China; however, the mechanisms underlying the effects of gastrodin have yet to be fully elucidated.Objective To explore the therapeutic efficiency of gastrodin as an antihypertens
Externí odkaz:
https://doaj.org/article/d2a3c571ab7e475ba6aa6c750aadb8cb
Autor:
Nanhui Xu, Qiurong Xie, Youqin Chen, Jiapeng Li, Xiuli Zhang, Huifang Zheng, Ying Cheng, Meizhu Wu, Aling Shen, Lihui Wei, Mengying Yao, Yanyan Yang, Thomas J. Sferra, Anjum Jafri, Yi Fang, Jun Peng
Publikováno v:
Pharmaceuticals, Vol 17, Iss 9, p 1200 (2024)
Gastrodin, a highly potent compound found in the traditional Chinese medicine Gastrodia elata Blume, exhibits significant antihypertensive properties. However, its role and the mechanism behind its protective effects on hypertensive cardiac condition
Externí odkaz:
https://doaj.org/article/f8795ecbeb5746f592c4dc0c5c51c3c6
Autor:
Qihong Liu, Danfeng Ke, Youqin Chen, Aling Shen, Liya Liu, Lunan Hu, Yan Ren, Wenyi Fang, Peilin Zhao, Thomas J. Sferraf, Yunfeng Luo, Xiao Ke
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Slow transit constipation (STC) is a common and debilitating condition characterized by delayed colonic transit and difficulty in fecal expulsion, significantly impacting patients’ physical and mental wellbeing as well as their overall quality of l
Externí odkaz:
https://doaj.org/article/1a7653a4247443cc9e766c157945ca10
Autor:
Aling Shen, Meizhu Wu, Farman Ali, Zhi Guo, Yi Fang, Yuting Zhou, Siyu Zhang, Wenqiang Zhang, Ying Wen, Min Yu, Jun Peng, Keji Chen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract The effects and underlying mechanisms of gastrodin treatment on hypertensive vascular dysfunction and proliferation of vascular smooth muscle cells (VSMCs) were determined in vitro and in vivo. Using a pharmacological target network interact
Externí odkaz:
https://doaj.org/article/6e734266f8a6410589aa43e8f8341890
Autor:
Yuying Han, Liya Liu, Youqin Chen, Huifang Zheng, Mengying Yao, Liujing Cao, Thomas J. Sferra, Xiao Ke, Jun Peng, Aling Shen
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Qing Hua Chang Yin (QHCY) is a famous formula of traditional Chinese medicine (TCM) and has been proven to have protective effect on ulcerative colitis. However, its protective effect and potential therapeutic mechanisms in chronic coliti
Externí odkaz:
https://doaj.org/article/de620078f22e4fcaadd8fbba993eaef9
Autor:
Liya Liu, Youqin Chen, Ying Cheng, Meizhu Wu, Jie Li, Jiapeng Li, Thomas Joseph Sferra, Senthilkumar Sankararaman, Jianfeng Chu, Aling Shen, Jun Peng
Publikováno v:
Pharmacological Research - Modern Chinese Medicine, Vol 7, Iss , Pp 100230- (2023)
Background: 5-Fluorouracil (5-FU) is one of the most commonly prescribed anticancer agents. However, intestinal mucositis is a well-known adverse event, which limits its therapeutic use. Refined Baohe formula (RBF) is derived from Baohe Pills with a
Externí odkaz:
https://doaj.org/article/22b15ddd515a4e1f90679cbbbb0a43bb