Zobrazeno 1 - 5
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pro vyhledávání: '"Aline Vitrac"'
Autor:
Aline Vitrac, Isabelle Cloëz-Tayarani
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-7 (2018)
Abstract The mammalian brain is a very complex organ containing an estimated 200 billion cells in humans. Therefore, studying human brain development has become very challenging given all the data that are available from different approaches, notably
Externí odkaz:
https://doaj.org/article/917c8468e34548e08097be9f6ec8a499
Autor:
Aline Vitrac, Claire S. Leblond, Thomas Rolland, Freddy Cliquet, Alexandre Mathieu, Anna Maruani, Richard Delorme, Michael Schön, Andreas M. Grabrucker, Conny van Ravenswaaij-Arts, Katy Phelan, Anne-Claude Tabet, Thomas Bourgeron
Publikováno v:
European Journal of Medical Genetics
European Journal of Medical Genetics, 2023, 66 (5), pp.104732. ⟨10.1016/j.ejmg.2023.104732⟩
European journal of medical genetics, 66(5):104732. ELSEVIER SCIENCE BV
European Journal of Medical Genetics, 2023, 66 (5), pp.104732. ⟨10.1016/j.ejmg.2023.104732⟩
European journal of medical genetics, 66(5):104732. ELSEVIER SCIENCE BV
International audience; SHANK3-related Phelan-McDermid syndrome (PMS) is caused by a loss of the distal part of chromosome 22, including SHANK3, or by a pathological SHANK3 variant. There is an important genetic and phenotypic diversity among patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c520e4e6644ca23d1a26e1ae4c83543
https://doi.org/10.1016/j.ejmg.2023.104732
https://doi.org/10.1016/j.ejmg.2023.104732
Humanized Chimeric Mouse Models to Study Human Neural Development and Pathogenesis of Brain Diseases
Publikováno v:
Translational Research Methods in Neurodevelopmental Disorders
Translational Research Methods in Neurodevelopmental Disorders, 185, Springer US, pp.135-158, 2022, Neuromethods, 978-1-0716-2569-9. ⟨10.1007/978-1-0716-2569-9_8⟩
Neuromethods ISBN: 9781071625682
Translational Research Methods in Neurodevelopmental Disorders, 185, Springer US, pp.135-158, 2022, Neuromethods, 978-1-0716-2569-9. ⟨10.1007/978-1-0716-2569-9_8⟩
Neuromethods ISBN: 9781071625682
International audience; The development of humanized neural chimeric mouse models consists in grafting human neuronal progenitor cells (NPC) or differentiated neurons derived from induced pluripotent stem cells (iPSC) into the mouse brain at differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce6d9b214021251c18dfdd3dde760ff3
https://hal-pasteur.archives-ouvertes.fr/pasteur-03845354/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-03845354/document
A chimeric mouse model to study human iPSC-derived neurons: the case of a truncating SHANK3 mutation
Autor:
Jean-Pierre Bourgeois, Nathalie Lemière, Stéphanie Pons, Isabelle Cloëz-Tayarani, Uwe Maskos, Marta Balkota, Aline Vitrac, Célia Raïs, Thomas Bourgeron
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.13315. ⟨10.1038/s41598-020-70056-4⟩
Scientific Reports, 2020, 10 (1), pp.13315. ⟨10.1038/s41598-020-70056-4⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.13315. ⟨10.1038/s41598-020-70056-4⟩
Scientific Reports, 2020, 10 (1), pp.13315. ⟨10.1038/s41598-020-70056-4⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Using human induced pluripotent stem cells (iPSC), recent studies have shown that the events underlying autism spectrum disorders (ASD) can occur during neonatal development. We previously analyzed the iPSC-derived pyramidal cortical neurons of a sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf024ed1f1231f1bcc0ef8685d5c21f
https://hal-pasteur.archives-ouvertes.fr/pasteur-02913616/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-02913616/document
Autor:
Anne Boland, Hany Goubran-Botros, Aurélie Poulet, Alexandra Benchoua, Ekaterina Atanasova, Anne Biton, Gwenaëlle André-Leroux, Richard Delorme, Aline Vitrac, Isabelle Cloëz-Tayarani, Anne Danckaert, Nathalie Lemière, Jean-Yves Tinevez, Laura Gouder, Claire S. Leblond, Thomas Bourgeron, Jean-François Deleuze
Publikováno v:
Scientific Reports
Scientific Reports, 2019, 9 (1), pp.1-11. ⟨10.1038/s41598-018-36993-x⟩
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.1-11. ⟨10.1038/s41598-018-36993-x⟩
Scientific Reports 1 (9), 1-11. (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, 2019, 9 (1), pp.1-11. ⟨10.1038/s41598-018-36993-x⟩
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.1-11. ⟨10.1038/s41598-018-36993-x⟩
Scientific Reports 1 (9), 1-11. (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
The synaptic protein SHANK3 encodes a multidomain scaffold protein expressed at the postsynaptic density of neuronal excitatory synapses. We previously identified de novo SHANK3 mutations in patients with autism spectrum disorders (ASD) and showed th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d681872562c115c67b72f20a5f73f14d
https://hal.science/hal-02010139
https://hal.science/hal-02010139