Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Aline Sahr"'
Autor:
Quang Vinh Ngo, Larissa Faass, Aline Sähr, Dagmar Hildebrand, Tatjana Eigenbrod, Klaus Heeg, Dennis Nurjadi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/1549f58e4c0f4b959707465597373162
Autor:
Caroline Arnold, Klaus Heeg, Julia Strebovsky, Aline Sahr, Holger Bartz, Claus Kaiser, Alexander H. Dalpke, Sabine J. Wölfle
Publikováno v:
European Journal of Immunology. 41:413-424
During infection, TLR agonists are released and trigger mature as well as differentiating innate immune cells. Early encounter with TLR agonists (R848; LPS) blocks conventional differentiation of CD14(+) monocytes into immature dendritic cells (iDCs)
Publikováno v:
Cell Communication and Signaling, Vol 10, Iss 1, p 22 (2012)
Cell Communication and Signaling : CCS
Cell Communication and Signaling : CCS
Background Lipopolysaccharide (LPS)-triggered Toll-like receptor (TLR) 4-signalling belongs to the key innate defence mechanisms upon infection with Gram-negative bacteria and triggers the subsequent activation of adaptive immunity. There is an activ
Autor:
Sabrina Klein, Benedict Morath, Daniel Weitz, Patrick A. Schweizer, Aline Sähr, Klaus Heeg, Sébastien Boutin, Dennis Nurjadi
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Persistent infections caused by Staphylococcus aureus remain a clinical challenge. Adaptational mechanisms of the pathogen influencing infection persistence, treatment success, and clinical outcome in these types of infections by S. aureus have not b
Externí odkaz:
https://doaj.org/article/059014b7832c4e62935e6436ebca815b
Autor:
Quang Vinh Ngo, Larissa Faass, Aline Sähr, Dagmar Hildebrand, Tatjana Eigenbrod, Klaus Heeg, Dennis Nurjadi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Staphylococcus aureus is one of the clinically most relevant pathogens causing infections. Humans are often exposed to S. aureus. In approximately one-third of the healthy population it can be found on the skin either for long or short periods as col
Externí odkaz:
https://doaj.org/article/26f9d96ccd59412ab0078931db9e3276
Autor:
Dagmar Hildebrand, Jana Böhringer, Eva Körner, Ute Chiriac, Sandra Förmer, Aline Sähr, Torsten Hoppe-Tichy, Klaus Heeg, Dennis Nurjadi
Publikováno v:
Antibiotics, Vol 11, Iss 5, p 581 (2022)
The severe course of bloodstream infections with Gram-negative bacilli can lead to organ dysfunctions and compromise the integrity of the vascular barrier, which are the hallmarks of sepsis. This study aimed to investigate the potential effect of cef
Externí odkaz:
https://doaj.org/article/45666f82f8fb495bbc843ac52f7f04c2
Autor:
Lars Johannes Krall, Sabrina Klein, Sébastien Boutin, Chia Ching Wu, Aline Sähr, Megan L. Stanifer, Steeve Boulant, Klaus Heeg, Dennis Nurjadi, Dagmar Hildebrand
Publikováno v:
Pathogens, Vol 10, Iss 12, p 1645 (2021)
Escherichia coli is one of the most prevalent pathogens, causing a variety of infections including bloodstream infections. At the same time, it can be found as a commensal, being part of the intestinal microflora. While it is widely accepted that pat
Externí odkaz:
https://doaj.org/article/cb2cd12d3e6d4018b7338fb89db835b3
Autor:
Dagmar Hildebrand, Mariel-Esther Eberle, Sabine Marie Wölfle, Franziska Egler, Delal Sahin, Aline Sähr, Konrad A. Bode, Klaus Heeg
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Antigen-presenting cells (APCs) regulate the balance of our immune response toward microbes. Whereas immunogenic APCs boost inflammation and activate lymphocytes, the highly plastic cells can switch into a tolerogenic/suppressive phenotype that dampe
Externí odkaz:
https://doaj.org/article/9f7c45294ed547eaaaa5990ce705192a
Autor:
Katharina Giesbrecht, Mariel-Esther Eberle, Sabine J. Wölfle, Delal Sahin, Aline Sähr, Valerie Oberhardt, Zach Menne, Konrad A. Bode, Klaus Heeg, Dagmar Hildebrand
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
During infection pathogen-associated molecular patterns activate immune cells to initiate a cascade of reactions leading to inflammation and the activation of the adaptive immune response culminating in the elimination of foreign pathogens. However,
Externí odkaz:
https://doaj.org/article/18a228181dda4a62bde0964f29f534dd