Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Aline Roch"'
Autor:
Philipp S. Lienemann, Queralt Vallmajo‐Martin, Panagiota Papageorgiou, Ulrich Blache, Stéphanie Metzger, Anna‐Sofia Kiveliö, Vincent Milleret, Ana Sala, Sylke Hoehnel, Aline Roch, Raphael Reuten, Manuel Koch, Olaia Naveiras, Franz E. Weber, Wilfried Weber, Matthias P. Lutolf, Martin Ehrbar
Publikováno v:
Advanced Science, Vol 7, Iss 7, Pp n/a-n/a (2020)
Abstract The treatment of bone defects with recombinant bone morphogenetic protein‐2 (BMP‐2) requires high doses precluding broad clinical application. Here, a bioengineering approach is presented that strongly improves low‐dose BMP‐2‐based
Externí odkaz:
https://doaj.org/article/ff1b5c7bb89f4cc493ad1ee1b1a8a396
Autor:
Aline Roch, Sonja Giger, Mukul Girotra, Vasco Campos, Nicola Vannini, Olaia Naveiras, Samy Gobaa, Matthias P. Lutolf
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Haematopoietic stem cell (HSC) self-renewal is not sufficiently understood to recapitulate in vitro. Here, the authors generate gene signature and cell cycle hallmarks of single murine HSCs, and use identified endothelial receptors Esam and JamC as s
Externí odkaz:
https://doaj.org/article/2a3e06912cf94e5189f5b67d9ba35d31
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8225 (2020)
Hematopoietic stem cells (HSCs) are responsible for life-long production of all mature blood cells. Under homeostasis, HSCs in their native bone marrow niches are believed to undergo asymmetric cell divisions (ACDs), with one daughter cell maintainin
Externí odkaz:
https://doaj.org/article/f7fbc2b3eb6243d2946e740460770a53
Autor:
Nicola Vannini, Mukul Girotra, Olaia Naveiras, Gennady Nikitin, Vasco Campos, Sonja Giger, Aline Roch, Johan Auwerx, Matthias P. Lutolf
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Haematopoietic stem cells rely on glycolysis for their energy demands but whether this affects their fate is unknown. Here, the authors show that forcing the cells to rely on glycolysis is important for self-renewal and that this involves a reduction
Externí odkaz:
https://doaj.org/article/b081f3f436004a1183c52fe48a38b2c1
Autor:
Daniel C Kirouac, Caryn Ito, Elizabeth Csaszar, Aline Roch, Mei Yu, Edward A Sykes, Gary D Bader, Peter W Zandstra
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp n/a-n/a (2010)
Intercellular (between cell) communication networks maintain homeostasis and coordinate regenerative and developmental cues in multicellular organisms. Despite the importance of intercellular networks in stem cell biology, their rules, structure and
Externí odkaz:
https://doaj.org/article/58beec843042450bbc1c0ff43879ba37
Autor:
Allen Goodman, Michael C. Kolios, Holger Hennig, Michael J. Parsons, Anne Wilson, Olaf Wolkenhauer, Shantanu Singh, Stefanie Siegert, Anne E. Carpenter, Joseph A. Sebastian, Ruben N. Pinto, Tracey R. Turner, Olga Mykhailova, Jason P. Acker, Minh Doan, Paul Rees, Juan C. Caicedo, Aline Roch, Claire McQuin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 35, pp. 21381-21390
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance We developed a strategy to avoid human subjectivity by assessing the quality of red blood cells using imaging flow cytometry and deep learning. We successfully automated traditional expert assessment by training a computer with example i
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8225, p 8225 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 21
International Journal of Molecular Sciences
Volume 21
Issue 21
Hematopoietic stem cells (HSCs) are responsible for life-long production of all mature blood cells. Under homeostasis, HSCs in their native bone marrow niches are believed to undergo asymmetric cell divisions (ACDs), with one daughter cell maintainin
Autor:
Aline Rocha Vieira, Aline Furtado Oliveira, Fabiana Vieira Lima Solino Pessoa, Beatriz Nogueira Messias de Miranda, André Rolim Baby
Publikováno v:
Scientia Pharmaceutica, Vol 92, Iss 3, p 43 (2024)
Different reaction control methods for producing nano/microstructures of poly(butyl cyanoacrylate) (PBCA) have been studied, focusing on pH and monomer-to-initiator ratios. However, these methods often require multiple steps and reagents. In the synt
Externí odkaz:
https://doaj.org/article/8f3281397ef940609f0e109113300376
Autor:
Cacang Suarna, Nicholas J. Magon, Sophie Claire Waldvogel, Mark J. Koury, Jessica Maire, Aline Roch, Beat A. Imhof, Roland Stocker, Anita Ayer, Marc Schapira
Publikováno v:
JCI Insight. 4
The RBC storage lesion is a multiparametric response that occurs during storage at 4°C, but its impact on transfused patients remains unclear. In studies of the RBC storage lesion, the temperature transition from cold storage to normal body temperat
Publikováno v:
Human Nutrition & Metabolism, Vol 35, Iss , Pp 200249- (2024)
Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) supplementation has been used to improve cognitive outcomes in diseases associated with cognition. However, the influence of APOEε4 genotype on these relationships remains unclear. Therefore
Externí odkaz:
https://doaj.org/article/c13a78aa7b2d47bb9ca59e304d57d10a