Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Aline Renata Pavan"'
Autor:
Andressa Francielli Bonjorno, Aline Renata Pavan, Guilherme F. S. Fernandes, Cauê Benito Scarim, Daniele Castagnolo, Jean Leandro Dos Santos
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Tuberculosis (TB) has claimed more lives over the course of two millennia than any other infectious disease worldwide. In 2021, the World Health Organization (WHO) estimated that 10.6 million people were diagnosed with TB, resulting in the deaths of
Externí odkaz:
https://doaj.org/article/985cd9fc9ede450fa7ddc5825874ea01
Autor:
Aline Renata Pavan, Juliana Romano Lopes, Carlos Henrique Lima Imperador, Chung Man Chin, Jean Leandro dos Santos
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/abea4a4c85d149b1afc5059ed5cf23f2
Autor:
Barbara Terroni, Luis Henrique Oliveira de Moraes, Aline Renata Pavan, Gerson Jhonatan Rodrigues, Jean Leandro Dos Santos
Publikováno v:
Pharmaceuticals, Vol 15, Iss 11, p 1311 (2022)
Vascular endothelium is a protective layer of cells lining the lumen of blood vessels that plays important roles by releasing factors responsible for controlling the vascular tone, regulating the expression of pro-inflammatory cytokines, and expressi
Externí odkaz:
https://doaj.org/article/feef6a96110f4b589d140c4393c37fe1
Autor:
Beatriz Silva Urias, Aline Renata Pavan, Gabriela Ribeiro Albuquerque, Igor Muccilo Prokopczyk, Tânia Mara Ferreira Alves, Thais Regina Ferreira de Melo, Geraldo Rodrigues Sartori, João Hermínio Martins da Silva, Chung Man Chin, Jean Leandro Dos Santos
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1260 (2022)
Histone deacetylases (HDAC) are epigenetic enzymes responsible for repressing gene expression through the deacetylation of histone lysine residues. Therefore, inhibition of HDACs has become an interesting approach for the treatment of several disease
Externí odkaz:
https://doaj.org/article/e217a6e15fa74663bcfd8c700da2588a
Autor:
Natália Lourenço de Freitas, Maria Gabriela Deberaldini, Diana Gomes, Aline Renata Pavan, Ângela Sousa, Jean Leandro Dos Santos, Christiane P. Soares
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
The role of epigenetic modifications on the carcinogenesis process has received a lot of attention in the last years. Among those, histone acetylation is a process regulated by histone deacetylases (HDAC) and histone acetyltransferases (HAT), and it
Externí odkaz:
https://doaj.org/article/5bf77e0de3e943c08bf6b9051bc44f1e
Autor:
Leandro Augusto Rosseto, Maria Elisa Lopes Pires, Aylime Castanho Bolognesi Melchior, Priscila Longhin Bosquesi, Aline Renata Pavan, Sisi Marcondes, Man Chin Chung, Jean Leandro dos Santos
Publikováno v:
Molecules, Vol 20, Iss 10, Pp 18185-18200 (2015)
Thrombosis is the main outcome of many cardiovascular diseases. Current treatments to prevent thrombotic events involve the long-term use of antiplatelet drugs. However, this therapy has several limitations, thereby justifying the development of new
Externí odkaz:
https://doaj.org/article/a2db657dc6bb4d2f83d64b2875ca34d9
Autor:
Guilherme Felipe Santos Fernandes, Gabriel Dalio Bernardes Silva, Aline Renata Pavan, Diego Eidy Chiba, Chung Man Chin, Jean Leandro Dos Santos
Publikováno v:
Nutrients, Vol 9, Iss 11, p 1201 (2017)
Resveratrol (RVT) is one of the main natural compounds studied worldwide due to its potential therapeutic use in the treatment of many diseases, including cancer, diabetes, cardiovascular diseases, neurodegenerative diseases and metabolic disorders.
Externí odkaz:
https://doaj.org/article/d03fdfab29f2428ca36fea83f55b09ad
Autor:
Aline Renata Pavan, Gabriel Dalio Bernardes da Silva, Daniela Hartmann Jornada, Diego Eidy Chiba, Guilherme Felipe dos Santos Fernandes, Chung Man Chin, Jean Leandro dos Santos
Publikováno v:
Nutrients, Vol 8, Iss 11, p 628 (2016)
Resveratrol and curcumin are natural products with important therapeutic properties useful to treat several human diseases, including cancer. In the last years, the number of studies describing the effect of both polyphenols against cancer has increa
Externí odkaz:
https://doaj.org/article/a3b298a07aaa4ae488b11dbcaff38279
Publikováno v:
Current Organic Chemistry. 25:1853-1867
Nowadays, boron-containing compounds have gained researchers’ attention because of the wide versatility and applicability of this element in both organic and medicinal chemistry. Since its discovery, its use in medicinal chemistry was neglected bec
Publikováno v:
Expert opinion on drug discovery. 17(11)
Sickle cell anemia (SCA) is a hematological genetic disorder caused by a mutation in the gene of the β-globin. Pharmacological treatments will continue to be an important approach, including the strategy to induce fetal hemoglobin (HbF). Here, we an