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Follow Up On CD8-Depleted Donor-Lymphocyte Infusions After T-Cell Depleted Allogeneic Hemopoietic Stem Cell Transplantation

Autor: Eva Wagner, Daniela Wehler, Wolfgang Herr, Aline N Lay, Timo Schmitt, Matthias Theobald, Karin Kolbe, Ralf G. Meyer

Publikováno v: Blood. 122:4526-4526

We applied prophylactic CD8-depleted (CD8depl) donor lymphocyte infusions (DLI) in the setting of T-cell depleted reduced-intensity allogeneic hematopoietic stem cell transplantation (HSCT) in a phase I/II trial. T-cell depletion was carried out by t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bfb49e34c308a2840cf4cf5f322392b6
https://doi.org/10.1182/blood.v122.21.4526.4526

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Long-Term Persistence of Functionally Altered GPI-Anchor Negative T-Cell Subsets After Alemtuzumab-Based T-Cell Depleted Hematopoietic Stem Cell Transplantation

Autor: Julia Hemmerling, Eva Wagner, Diana Wolff, Timo Schmitt, Ralf G. Meyer, Christoph Huber, Aline N Lay, Wolfgang Herr

Publikováno v: Blood. 114:2438-2438

Abstract 2438 Poster Board II-415 The anti CD52 antibody alemtuzumab is frequently used for in vivo T cell depletion (TCD) in the context of allogeneic hematopoietic stem cell transplantation (HSCT). We have recently demonstrated the persistence of C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea04e9422a9f6a1a6fd64ed6aff86dbc
https://doi.org/10.1182/blood.v114.22.2438.2438

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Reconstitution of CD52-Negative CD4 T Cells after Alemtuzumab-Based T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

Autor: Ralf G. Meyer, Abdo Konur, Julia Hemmerling, Timo Schmitt, Klaus Bender, Wolfgang Herr, Christoph Huber, Eva Wagner, Aline N Lay, Sina Wenzel

Publikováno v: Blood. 112:1182-1182

The human CD52 molecule is the target of the monoclonal antibody Alemtuzumab, which is used for treating patients with chemo-refractory chronic lymphocytic leukemia as well as for T cell depletion (TCD) in the context of allogeneic hematopoietic stem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::272cb96179cc0e041b414257885321ad
https://doi.org/10.1182/blood.v112.11.1182.1182

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