Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Aline Moosmann"'
Autor:
Sylvia Wagner, Thorsten Knoll, Linda Elberskirch, Hagen von Briesen, Nadine Wilhelm, Aline Moosmann
A major challenge of drug discovery is to overcome the mucus barrier, which is lined the surface of the gastrointestinal tract. The ability to overcome this barrier must be tested in preclinical in vitro models, prior to in vivo studies. Therefore, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4385a52998e12091b0212e75765b1243
https://publica.fraunhofer.de/handle/publica/260805
https://publica.fraunhofer.de/handle/publica/260805
Autor:
Hagen von Briesen, Rebecca Buchholz, Klaus Langer, Rebecca Niehaus, Dennis Mulac, Michael R. Sperling, Arno Wiehe, Judith Söbbing, Uwe Karst, Sabrina Kröger, Aline Moosmann, Ann-Christin Niehoff, Jonas Grünebaum, Sylvia Wagner
Publikováno v:
Analytica Chimica Acta. 938:106-113
Limited drug penetration into tumor tissue is a significant factor to the effectiveness of cancer therapy. Tumor spheroids, a 3D cell culture model system, can be used to study drug penetration for pharmaceutical development. In this study, a method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c87b225b2fe1f448e5d0103e85b586ff
https://doi.org/10.1016/j.aca.2016.07.021
https://doi.org/10.1016/j.aca.2016.07.021
Autor:
Nerea Ferreirós, Thomas Ulshöfer, Michael J. Parnham, Sylvia Wagner, Matthias G. Wacker, Susanne Beyer, Astrid S. Kahnt, Aline Moosmann
Publikováno v:
Pharmaceutical research. 32(12)
The contribution of permeability and drug release to drug targeting were investigated in the course of development of a nanosized formulation of the anti-inflammatory compound TMP-001, for the local treatment in the gastrointestinal tract.TMP-001 was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f83dfba36d9ad95f325c0206bb9038
https://pubmed.ncbi.nlm.nih.gov/26216175
https://pubmed.ncbi.nlm.nih.gov/26216175
Autor:
Dennis Mulac, Michael R. Sperling, Olga Reifschneider, Hagen von Briesen, Judith Söbbing, Klaus Langer, Franziska Blaske, Sylvia Wagner, Christoph A. Wehe, Uwe Karst, Arno Wiehe, Aline Moosmann, Ann-Christin Niehoff
Publikováno v:
Metallomics : integrated biometal science. 6(1)
In this study, the cellular uptake of the second generation photosensitizer 5,10,15,20-tetrakis(3-hydroxyphenyl)porphyrin (mTHPP) was investigated using laser ablation coupled to inductively coupled plasma mass spectrometry (LA-ICP-MS) at a spatial r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d3c6a3f0d8570cf1e07104e008949bb
https://pubmed.ncbi.nlm.nih.gov/24311052
https://pubmed.ncbi.nlm.nih.gov/24311052