Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Aline Jary"'
Publikováno v:
CHIMIA, Vol 57, Iss 5 (2003)
N-alkylated-?-amino acids and methyl esters are a special class of building blocks used for the production of combinatorial libraries. They have two reactive groups for their incorporation into chemical scaffolds and they bear on their 3-atom backbon
Externí odkaz:
https://doaj.org/article/1925b4a6741442e8bf546ae7c6b944e6
Autor:
Robin A. Fairhurst, Pascal Furet, Patricia Imbach-Weese, Frédéric Stauffer, Heinrich Rueeger, Clive McCarthy, Sebastien Ripoche, Susanne Oswald, Bertrand Arnaud, Aline Jary, Michel Maira, Christian Schnell, Daniel A. Guthy, Markus Wartmann, Michael Kiffe, Sandrine Desrayaud, Francesca Blasco, Toni Widmer, Frank Seiler, Sascha Gutmann, Mark Knapp, Giorgio Caravatti
Publikováno v:
Journal of Medicinal Chemistry. 65:8345-8379
Balanced pan-class I phosphoinositide 3-kinase inhibition as an approach to cancer treatment offers the prospect of treating a broad range of tumor types and/or a way to achieve greater efficacy with a single inhibitor. Taking buparlisib as the start
Autor:
Pierre Jean Souquet, Sang-We Kim, Johan F. Vansteenkiste, Anna Robeva, Aline Jary, Sabine Glaser, Alejandro Yovine, Juergen Wolf
Publikováno v:
Cancer Research. 82:CT558-CT558
Background: MET dysregulation is a poor prognostic factor in advanced non-small cell lung cancer (NSCLC). MET exon 14 skipping (METex14) mutations occur in ~3% of patients with NSCLC. There is limited evidence of the efficacy of standard therapies, s
Autor:
Charalambos Andreadis, Michael R. Bishop, Edmund K. Waller, Peter Borchmann, Veronika Bachanova, John M. Magenau, Samantha Jaglowski, Koji Kato, Isabelle Fleury, Richard T. Maziarz, Marie José Kersten, Oezlem Anak, Constantine S. Tam, Jufen Chu, Aline Jary, Jason R. Westin, Joseph P. McGuirk, Ulrich Jaeger, Harald Holte, Stephan Mielke, Koen van Besien, Joy Ho, Gilles Salles, Stephen J. Schuster, Takanori Teshima, Nina D. Wagner-Johnston, Stephen Ronan Foley, Kensei Tobinai
Publikováno v:
Biology of Blood and Marrow Transplantation. 25:S20-S21
Background Tisagenlecleucel, a chimeric antigen receptor T-cell therapy, has demonstrated efficacy and manageable safety in adult patients (pts) with relapsed/refractory diffuse large B-cell lymphoma (r/r DLBCL) in the global, multicenter, pivotal, p
Autor:
Takanori Teshima, Koen van Besien, Peter Borchmann, Joseph P. McGuirk, Stephan Mielke, Özlem Anak, John M. Magenau, Jufen Chu, Richard T. Maziarz, Nina D. Wagner-Johnston, Aline Jary, P. Joy Ho, Gilles Salles, Edmund K. Waller, Veronika Bachanova, Jason R. Westin, Marie José Kersten, Isabelle Fleury, Stephen Ronan Foley, Constantine S. Tam, Stephen J. Schuster, Harald Holte, Koji Kato, Charalambos Andreadis, Michael R. Bishop, Ulrich Jaeger, Samantha Jaglowski, Kensei Tobinai
Publikováno v:
Blood. 132:1684-1684
BACKGROUND JULIET (NCT02445248) is a single-arm, open-label, multicenter, global, pivotal phase 2 trial of tisagenlecleucel, a chimeric antigen receptor (CAR)-T cell therapy targeting CD19, that has shown a high rate of durable complete responses (CR
Publikováno v:
CHIMIA, Vol 57, Iss 5 (2003)
N-alkylated-?-amino acids and methyl esters are a special class of building blocks used for the production of combinatorial libraries. They have two reactive groups for their incorporation into chemical scaffolds and they bear on their 3-atom backbon