Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Aline Fiebig-Comyn"'
Autor:
Jong-Hee Lee, Sarah Laronde, Tony J. Collins, Zoya Shapovalova, Borko Tanasijevic, Jamie D. McNicol, Aline Fiebig-Comyn, Yannick D. Benoit, Jung Bok Lee, Ryan R. Mitchell, Mickie Bhatia
Publikováno v:
Cell Reports, Vol 19, Iss 1, Pp 20-35 (2017)
Human pluripotent stem cells (hPSCs) have been reported in naive and primed states. However, the ability to generate mature cell types remains the imperative property for utility of hPSCs. Here, we reveal that the naive state enhances self-renewal wh
Externí odkaz:
https://doaj.org/article/632c81e24b1a4140a186435928fb0d4b
Autor:
Kyle R. Salci, Jung Bok Lee, Ryan R. Mitchell, Luca Orlando, Aline Fiebig-Comyn, Zoya Shapovalova, Mickie Bhatia
Publikováno v:
Stem Cell Research, Vol 15, Iss 1, Pp 221-230 (2015)
The combination of OCT4 expression and short-term exposure to reprogramming media induces a state of transcriptional plasticity in human fibroblasts, capable of responding to changes in the extracellular environment that facilitate direct cell fate c
Externí odkaz:
https://doaj.org/article/d5cbb69d81844058a598e4dea421af9c
Autor:
Jong-Hee Lee, Ryan R. Mitchell, Jamie D. McNicol, Zoya Shapovalova, Sarah Laronde, Borko Tanasijevic, Chloe Milsom, Fanny Casado, Aline Fiebig-Comyn, Tony J. Collins, Karun K. Singh, Mickie Bhatia
Publikováno v:
Cell Reports, Vol 11, Iss 9, Pp 1367-1376 (2015)
The clinical applicability of direct cell fate conversion depends on obtaining tissue from patients that is easy to harvest, store, and manipulate for reprogramming. Here, we generate induced neural progenitor cells (iNPCs) from neonatal and adult pe
Externí odkaz:
https://doaj.org/article/b11aa922158d4166b81be9280ad2f0aa
Autor:
Kyle R. Salci, Jung Bok Lee, Ryan R. Mitchell, Luca Orlando, Aline Fiebig-Comyn, Zoya Shapovalova, Mickie Bhatia
Publikováno v:
Stem Cell Research, Vol 15, Iss 1, Pp 240-242 (2015)
The combination of OCT4 expression and short-term exposure to reprogramming media induces a state of transcriptional plasticity in human fibroblasts, capable of responding to changes in the extracellular environment. Here we provide characterization
Externí odkaz:
https://doaj.org/article/80384ffe987c4a9b9202a0b4b2f421c7
Autor:
Georgy Popov, Aline Fiebig-Comyn, Lukas Syriste, Dustin J. Little, Tatiana Skarina, Peter J. Stogios, Sarah Birstonas, Brian K. Coombes, Alexei Savchenko
Publikováno v:
Infect Immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdc45b17e0588b3c7e6b377b50f1333
https://doi.org/10.1128/iai.00094-23
https://doi.org/10.1128/iai.00094-23
Autor:
Georgy Popov, Aline Fiebig-Comyn, Lukas Syriste, Dustin J. Little, Tatiana Skarina, Peter J. Stogios, Sarah Birstonas, Brian K. Coombes, Alexei Savchenko
Publikováno v:
Infect Immun
The NleGs are the largest family of type 3 secreted effectors in attaching and effacing (A/E) pathogens, such as enterohemorrhagic Escherichia coli (EHEC), enteropathogenic E. coli, and Citrobacter rodentium. NleG effectors contain a conserved C-term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f0791c21853d442124e0dd36859481
https://doi.org/10.1128/iai.00505-22
https://doi.org/10.1128/iai.00505-22
Autor:
Michael S. Van Nieuwenhze, David Sychantha, Gerard D. Wright, Yen-Pang Hsu, Nicholas Waglechner, Wenliang Wang, Yves V. Brun, Elizabeth J. Culp, Brian K. Coombes, Aline Fiebig-Comyn, Kalinka Koteva
Publikováno v:
Nature. 578:582-587
Addressing the ongoing antibiotic crisis requires the discovery of compounds with novel mechanisms of action that are capable of treating drug-resistant infections1. Many antibiotics are sourced from specialized metabolites produced by bacteria, part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfb06264507a24b1d5818a4e465ec676
https://doi.org/10.1038/s41586-020-1990-9
https://doi.org/10.1038/s41586-020-1990-9
Autor:
Trevor C. Lau, Aline Fiebig-Comyn, Christopher R. Shaler, Jonathan D. Schertzer, Brian K. Coombes, Joseph B. McPhee
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 321(3)
It is commonly thought that obesity or a high-fat diet alters pathogenic bacteria and promotes inflammatory gut diseases. We found that lower dietary fiber is a key factor that expands a gut pathobiont linked to Crohn’s disease, independent of obes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a227be233901d2554ab126e084e560f
https://pubmed.ncbi.nlm.nih.gov/34280051
https://pubmed.ncbi.nlm.nih.gov/34280051
Autor:
Jakob Magolan, Shawn French, Aaron M. De Jong, Eric D. Brown, Brent S. Weber, Aline Fiebig-Comyn, Srinivas Dharavath, Brian K. Coombes, Amelia B.Y. Guo
Publikováno v:
Cell reports. 32(3)
Antibiotics halt the growth of bacteria by targeting core, essential physiology that is required for life on standard microbiological media. Many more biochemical and virulence processes, however, are required for bacteria to cause infection in a hos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c674f613336878945e3f1d7b3fb7f17
https://pubmed.ncbi.nlm.nih.gov/32698013
https://pubmed.ncbi.nlm.nih.gov/32698013
Autor:
Shawn French, Jakob Magolan, Eric D. Brown, Brian K. Coombes, Aaron M. De Jong, Aline Fiebig-Comyn, Amelia B.Y. Guo, Brent S. Weber, Srinivas Dharavath
Publikováno v:
SSRN Electronic Journal.
Antibiotics halt the growth of bacteria in the laboratory by targeting core, essential physiology that is required for life on standard microbiological media. Many more biochemical and virulence processes, however, are required for bacteria to cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83757080ba86b40ff7adaf60e882d3b5
https://doi.org/10.2139/ssrn.3526892
https://doi.org/10.2139/ssrn.3526892