Design, Synthesis and In Vitro Trypanocidal and Leishmanicidal Activities of 2‐(2‐Arylidene)hydrazono‐4‐oxothiazolidine‐5‐acetic Acid Derivatives

Autor: Luiz Felipe Gomes Rebello Ferreira, Muhammad Haroon, Muhammad Nawaz Tahir, Tashfeen Akhtar, Valéria Rêgo Alves Pereira, Fabiano Amaro de Sousa, Rafaela Salgado Ferreira, Rafael E. O. Rocha, Mabilly Cox Holanda de Barros Dias, Ana Cristina Lima Leite, Marcelo Zaldini Hernandes, Shahid Hameed, Paulo André Teixeira de Moraes Gomes, Aline C Santos

Publikováno v: ChemistrySelect. 4:13163-13172

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::adba5fa2bdbb276346208798cdd24491
https://doi.org/10.1002/slct.201902561

Pyrimidine Derivatives: QSAR Studies of Larvicidal Activity against Aedes aegypti

Autor: Zenaide Severina do Monte, Aline C Santos, Daniela Maria do Amaral Ferraz Navarro, Renata Priscila Costa Barros, Júlio César Ribeiro de Oliveira Farias de Aguiar, Valéria Rêgo Alves Pereira, Jéssica da Silva Nascimento, Sebastião J. de Melo, Luciana Scotti, Marcus Tullius Scotti, Emerson Peter da Silva Falcão

Publikováno v: Journal of the Brazilian Chemical Society.

The present study investigated the activity of pyrimidine derivatives against Aedes aegypti. Two compounds, 3c and 3d showed excellent larvicide activity. Additionally, quantitative structure-activity relationship (QSAR) models were built using multi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d9c264c773370bfc0cb9c34d316ccc3b
https://doi.org/10.21577/0103-5053.20200039

Reduction of the DNA damages, Hepatoprotective Effect and Antioxidant Potential of the Coconut Water, ascorbic and Caffeic Acids in Oxidative Stress Mediated by Ethanol

Autor: Adriano de Britto Chaves Filho, Rodrigo B. Santos, Humberto R. Matos, Railmara Pereira da Silva, Aline C Santos, Lucas S. Dantas, Isabella Fernanda Dantas Pinto, Danielle de Jesus Trindade, Felipe A M Otsuka, Vanderson S. Bispo

Publikováno v: Anais da Academia Brasileira de Ciências v.89 n.2 2017
Anais da Academia Brasileira de Ciências
Academia Brasileira de Ciências (ABC)
instacron:ABC
Anais da Academia Brasileira de Ciências, Volume: 89, Issue: 2, Pages: 1095-1109, Published: 15 MAY 2017
Anais da Academia Brasileira de Ciências, Iss 0

Hepatic disorders such as steatosis and alcoholic steatohepatitis are common diseases that affect thousands of people around the globe. This study aims to identify the main phenol compounds using a new HPLC-ESI+-MS/MS method, to evaluate some oxidati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4adeb86ec723be49abfc6b0e4cd6fc47
https://doi.org/10.1590/0001-3765201720160581

Composite Based on Biphasic Calcium Phosphate (HA/β-TCP) and Nanocellulose from the Açaí Tegument

Autor: Victor Soares Pereira, Carmen Gilda Barroso Tavares Dias, Sabina M C Andrade, Rachel Margalho Barreira Valentim, Marcos A. L. Reis, Maria Elizabeth Maués Dos Santos, Aline C Santos, Izael Pinho dos Santos

Publikováno v: Materials
Materials, Vol 11, Iss 11, p 2213 (2018)
Volume 11
Issue 11

The use of lignocellulosic remnants of the aç
aí
agro-business will benefit the environment with a precursor material for biomedical applications. Nanocellulose (NC) allows the biomimetic growth of biphasic ceramics on its surfa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16808ba652f3171b2b802af375c34cdf
https://pubmed.ncbi.nlm.nih.gov/30412992

Assessment of Leishmania cell lines expressing high levels of beta-galactosidase as alternative tools for the evaluation of anti-leishmanial drug activity

Autor: Thiago André Ramos dos Santos, Valéria Rêgo Alves Pereira, Danielle M.N. Moura, Osvaldo P. de Melo Neto, Aline C Santos

Publikováno v: Journal of Microbiological Methods. 166:105732

Leishmaniasis, caused by protozoa belonging to the genus Leishmania, is an important public health problem found in >90 countries and with still limited options for treatment. Development of new anti-leishmanial drugs is an urgent need and the identi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c8945b60aa1ea78462a452ce355c3cf
https://doi.org/10.1016/j.mimet.2019.105732