Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Aline, Dumuis"'
Autor:
Frank Yocca, Carlos M. Villalon, Andrew Sleight, Trevor Sharp, Pramod R. Saxena, Bryan Roth, John A. Peters, Stephen J. Peroutka, John Neumaier, Ewan Mylecharane, Derek N. Middlemiss, Graeme R. Martin, Luc Maroteaux, Klaus Peter Latté, Patrick P. A. Humphrey, Daniel Hoyer, Rebecca Hills, Katharine Herrick-Davis, Julie Hensler, René Hen, Paul R. Hartig, Michel Hamon, Mark Hamblin, Manfred Göthert, Richard M. Eglen, Aline Dumuis, Marlene L. Cohen, Amy Butler, Theresa Branchek, Joel Bockaert, Gordon Baxter, Nicholas M. Barnes, Rodrigo Andrade
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
5-HT receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on 5-HT receptors [198] and subsequently revised [180]) are, with the exception of the ionotropic 5-HT3 class, GPCRs where the endogenous agonist is 5-hydroxytryptamine. The diversi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4af4d3d745f0e8e57bd57986ad25334a
https://doi.org/10.2218/gtopdb/f1/2023.1
https://doi.org/10.2218/gtopdb/f1/2023.1
Autor:
Luis Segu, Marie-José Lecomte, Mathieu Wolff, Julie Santamaria, René Hen, Aline Dumuis, Sylvie Berrard, Joël Bockaert, Marie-Christine Buhot, Valérie Compan
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9529 (2010)
Patients suffering from dementia of Alzheimer's type express less serotonin 4 receptors (5-HTR(4)), but whether an absence of these receptors modifies learning and memory is unexplored. In the spatial version of the Morris water maze, we show that 5-
Externí odkaz:
https://doaj.org/article/2f69162edfaa458488b01dc7c6bb0cde
Autor:
Pramod R. Saxena, Patrick P.A. Humphrey, Joël Bockaert, Rebecca Hills, Sleight Andrew, Rodrigo Andrade, Amy S. Butler, Bryan L. Roth, Graeme R. Martin, Frank D. Yocca, Stephen J. Peroutka, Manfred Göthert, Julie Hensler, Carlos M. Villalón, Katharine Herrick-Davis, Luc Maroteaux, Richard M. Eglen, Paul R. Hartig, Nicholas M. Barnes, M. Hamon, Theresa Branchek, Aline Dumuis, Klaus Peter Latté, Mark W. Hamblin, Trevor Sharp, Ewan J. Mylecharane, John F. Neumaier, René Hen, John A. Peters, Marlene L. Cohen, Derek N. Middlemiss, Gordon Baxter, Daniel Hoyer
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2019
5-HT receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on 5-HT receptors [194] and subsequently revised [176]) are, with the exception of the ionotropic 5-HT3 class, GPCRs where the endogenous agonist is 5-hydroxytryptamine. The diversi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acc171822fcb3a73f3b0da9179a7a21b
https://doi.org/10.2218/gtopdb/f1/2019.4
https://doi.org/10.2218/gtopdb/f1/2019.4
Publikováno v:
Current Drug Targets. 13:28-52
Serotonin (5-HT) is a phylogenetically ancient transmitter implicated in many vital functions in human such as sleep, food intake, reproduction, nociception, regulation of mood and emotions as well as cognitive functions. Correspondingly, dysfunction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a14d526acebcbef1259419057a7fb8a3
https://doi.org/10.2174/138945012798868498
https://doi.org/10.2174/138945012798868498
Autor:
Jean-Philippe Pin, Aline Dumuis, Lucie P. Pellissier, Jean-Louis Banères, Eric Trinquet, Elisabeth Cassier, Philippe Marin, Sylvie Claeysen, Florence Gaven, Joël Bockaert, Gael Barthet
Publikováno v:
Journal of Biological Chemistry. 286:9985-9997
The discovery that class C G protein-coupled receptors (GPCRs) function as obligatory dimeric entities has generated major interest in GPCR oligomerization. Oligomerization now appears to be a common feature among all GPCR classes. However, the funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fc2cf937ccab94e5ff61e0201cd8bef
https://doi.org/10.1074/jbc.m110.201939
https://doi.org/10.1074/jbc.m110.201939
Autor:
Aline Dumuis, Maud Cochet, Ute Renner, Jakub Wlodarczyk, Evgeni Ponimaskin, Diethelm W. Richter, Elena Kvachnina
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1793:1646-1655
The 5-HT(7) receptor is the most recently described member of the serotonin receptor family. This receptor is mainly expressed in the thalamus, hypothalamus as well as in the hippocampus and cortex. In the present study, we demonstrate that the mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b58c7f34b825a2fd80a64cc292573f
https://doi.org/10.1016/j.bbamcr.2009.08.008
https://doi.org/10.1016/j.bbamcr.2009.08.008
Autor:
Sabrina Butt-Gueulle, Stephane Lemaitre, Cyril Daveu, Ronan Bureau, Alban Lepailleur, Véronique Lelong-Boulouard, Pascal Duchatelle, Bruno Pfeiffer, François Dauphin, Sylvain Rault, Michel Boulouard, Aline Dumuis, Frank Lezoualc'h
Publikováno v:
Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2009, 17 (6), pp.2607-22. ⟨10.1016/j.bmc.2008.11.045⟩
Bioorganic and Medicinal Chemistry, Elsevier, 2009, 17 (6), pp.2607-22. ⟨10.1016/j.bmc.2008.11.045⟩
International audience; Based on the definition of a 5-HT(4) receptor antagonist pharmacophore, a series of pyrrolo[1,2-a]thieno[3,2-e] and pyrrolo[1,2-a]thieno[2,3-e] pyrazine derivatives were designed, prepared, and evaluated to determine the prope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb8db7902e5d80abde4c9cbf5c8b4e54
https://doi.org/10.1016/j.bmc.2008.11.045
https://doi.org/10.1016/j.bmc.2008.11.045
Autor:
Paul E. Gold, Frank Lezoualc'h, Yael Marantz, Sharon Shacham, Silvia Noiman, Sylvain J. Robert, Joseph Rutkowski, Aline Dumuis, Joël Bockaert, Michael E. Ragozzino, Eric G. Mohler, Monique Gastineau
Publikováno v:
Neuropharmacology. 53:563-573
Recent evidence suggests that 5-hydroxytryptamine (5-HT)(4) receptor activity enhances cognition and provides neuroprotection. Here we report the effects of VRX-03011, a novel partial 5-HT(4) agonist, that is both potent (K(i) approximately 30 nM) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47071a0425a1e45627c3ec5ebe129c17
https://doi.org/10.1016/j.neuropharm.2007.06.016
https://doi.org/10.1016/j.neuropharm.2007.06.016
Autor:
Aimée Martin, Danielle Mesnier, Joël Bockaert, Aline Dumuis, Lara Joubert, Jean-Louis Banères
Publikováno v:
Journal of Biological Chemistry. 280:20253-20260
Serotonin 5-HT4(a) receptor, a G-protein-coupled receptor (GPCR), was produced as a functional isolated protein using Escherichia coli as an expression system. The isolated receptor was characterized at the molecular level by circular dichroism (CD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7adfd4938410ab0d098b872baec3d84
https://doi.org/10.1074/jbc.m412009200
https://doi.org/10.1074/jbc.m412009200
Publikováno v:
FEBS Letters. 546:65-72
All cell types express a great variety of G protein-coupled receptors (GPCRs) that are coupled to only a limited set of G proteins. This disposition favors cross-talk between transduction pathways. However, GPCRs are organized into functional units.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71af5ca11ee002a7599d87f6594afdd1
https://doi.org/10.1016/s0014-5793(03)00453-8
https://doi.org/10.1016/s0014-5793(03)00453-8