Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Alina Tscherne"'
Autor:
Sabrina Clever, Leonard Limpinsel, Christian Meyer zu Natrup, Lisa-Marie Schünemann, Georg Beythien, Malgorzata Rosiak, Kirsten Hülskötter, Katharina Manuela Gregor, Tamara Tuchel, Georgia Kalodimou, Astrid Freudenstein, Satendra Kumar, Wolfgang Baumgärtner, Gerd Sutter, Alina Tscherne, Asisa Volz
Publikováno v:
Viruses, Vol 16, Iss 3, p 417 (2024)
The sudden emergence of SARS-CoV-2 demonstrates the need for new vaccines that rapidly protect in the case of an emergency. In this study, we developed a recombinant MVA vaccine co-expressing SARS-CoV-2 prefusion-stabilized spike protein (ST) and SAR
Externí odkaz:
https://doaj.org/article/dce965dac07f41e881175ae99326794b
Autor:
Sabrina Clever, Lisa-Marie Schünemann, Federico Armando, Christian Meyer zu Natrup, Tamara Tuchel, Alina Tscherne, Malgorzata Ciurkiewicz, Wolfgang Baumgärtner, Gerd Sutter, Asisa Volz
Publikováno v:
Vaccines, Vol 12, Iss 1, p 52 (2024)
Aging is associated with a decline in immune system functionality. So-called immunosenescence may impair the successful vaccination of elderly people. Thus, improved vaccination strategies also suitable for an aged immune system are required. Modifie
Externí odkaz:
https://doaj.org/article/ef0ed1f946e847349fdcdb39a1bdf45f
Autor:
Mareike Kubinski, Jana Beicht, Thomas Gerlach, Amare Aregay, Albert D. M. E. Osterhaus, Alina Tscherne, Gerd Sutter, Chittappen Kandiyil Prajeeth, Guus F. Rimmelzwaan
Publikováno v:
Vaccines, Vol 12, Iss 1, p 105 (2024)
Tick-borne encephalitis (TBE) is a serious neurological disease caused by TBE virus (TBEV). Because antiviral treatment options are not available, vaccination is the key prophylactic measure against TBEV infections. Despite the availability of effect
Externí odkaz:
https://doaj.org/article/6995d27a9c67459589803e595b8ce85e
Autor:
Anahita Fathi, Christine Dahlke, Verena Krähling, Alexandra Kupke, Nisreen M. A. Okba, Matthijs P. Raadsen, Jasmin Heidepriem, Marcel A. Müller, Grigori Paris, Susan Lassen, Michael Klüver, Asisa Volz, Till Koch, My L. Ly, Monika Friedrich, Robert Fux, Alina Tscherne, Georgia Kalodimou, Stefan Schmiedel, Victor M. Corman, Thomas Hesterkamp, Christian Drosten, Felix F. Loeffler, Bart L. Haagmans, Gerd Sutter, Stephan Becker, Marylyn M. Addo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
In a clinical trial, Fathi et al. show that a booster vaccination with a vector vaccine candidate against the highly pathogenic Middle East Respiratory Syndrome coronavirus is safe and strongly improves the immunity generated by primary immunization.
Externí odkaz:
https://doaj.org/article/9c0741a645df4990aa04ffff02338df4
Autor:
Mareike Kubinski, Jana Beicht, Isabel Zdora, Jeannine Biermann, Christina Puff, Thomas Gerlach, Alina Tscherne, Wolfgang Baumgärtner, Albert D. M. E. Osterhaus, Gerd Sutter, Chittappen Kandiyil Prajeeth, Guus F. Rimmelzwaan
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTick-borne encephalitis virus (TBEV) is an important human pathogen that can cause a serious disease involving the central nervous system (tick-borne encephalitis, TBE). Although approved inactivated vaccines are available, the number of
Externí odkaz:
https://doaj.org/article/f30976dabf954191adc669ce1ae55027
Autor:
Christian Meyer zu Natrup, Alina Tscherne, Christine Dahlke, Malgorzata Ciurkiewicz, Dai-Lun Shin, Anahita Fathi, Cornelius Rohde, Georgia Kalodimou, Sandro Halwe, Leonard Limpinsel, Jan H. Schwarz, Martha Klug, Meral Esen, Nicole Schneiderhan-Marra, Alex Dulovic, Alexandra Kupke, Katrin Brosinski, Sabrina Clever, Lisa-Marie Schünemann, Georg Beythien, Federico Armando, Leonie Mayer, Marie L. Weskamm, Sylvia Jany, Astrid Freudenstein, Tamara Tuchel, Wolfgang Baumgärtner, Peter Kremsner, Rolf Fendel, Marylyn M. Addo, Stephan Becker, Gerd Sutter, Asisa Volz
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 24 (2022)
The SARS-CoV-2 spike (S) glycoprotein is synthesized as a large precursor protein and must be activated by proteolytic cleavage into S1 and S2. A recombinant modified vaccinia virus Ankara (MVA) expressing native, full-length S protein (MVA-SARS-2-S)
Externí odkaz:
https://doaj.org/article/c3dacfdcee5044c4a6d220158af4b33c
Autor:
Martin C. Langenmayer, Anna-Theresa Luelf-Averhoff, Lisa Marr, Sylvia Jany, Astrid Freudenstein, Silvia Adam-Neumair, Alina Tscherne, Robert Fux, Juan J. Rojas, Andreas Blutke, Gerd Sutter, Asisa Volz
Publikováno v:
Pathogens, Vol 12, Iss 7, p 867 (2023)
Influenza, a respiratory disease mainly caused by influenza A and B, viruses of the Orthomyxoviridae, is still a burden on our society’s health and economic system. Influenza A viruses (IAV) circulate in mammalian and avian populations, causing sea
Externí odkaz:
https://doaj.org/article/ed108fa0846b4fb79076124651caa712
Autor:
Georgia Kalodimou, Sylvia Jany, Astrid Freudenstein, Jan Hendrik Schwarz, Leonard Limpinsel, Cornelius Rohde, Alexandra Kupke, Stephan Becker, Asisa Volz, Alina Tscherne, Gerd Sutter
Publikováno v:
Viruses, Vol 15, Iss 5, p 1180 (2023)
The COVID-19 pandemic caused significant human health and economic consequences. Due to the ability of SARS-CoV-2 to spread rapidly and to cause severe disease and mortality in certain population groups, vaccines are essential for controlling the pan
Externí odkaz:
https://doaj.org/article/1273b01d73fc4963ac4a077943276725
Autor:
Berislav Bošnjak, Ivan Odak, Joana Barros-Martins, Inga Sandrock, Swantje I. Hammerschmidt, Marc Permanyer, Gwendolyn E. Patzer, Hristo Greorgiev, Rodrigo Gutierrez Jauregui, Alina Tscherne, Jan Hendrik Schwarz, Georgia Kalodimou, George Ssebyatika, Malgorzata Ciurkiewicz, Stefanie Willenzon, Anja Bubke, Jasmin Ristenpart, Christiane Ritter, Tamara Tuchel, Christian Meyer zu Natrup, Dai-Lun Shin, Sabrina Clever, Leonard Limpinsel, Wolfgang Baumgärtner, Thomas Krey, Asisa Volz, Gerd Sutter, Reinhold Förster
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Antigen-specific tissue-resident memory T cells (Trms) and neutralizing IgA antibodies provide the most effective protection of the lungs from viral infections. To induce those essential components of lung immunity against SARS-CoV-2, we tested vario
Externí odkaz:
https://doaj.org/article/76eb9b3576254d289905045704455f62
Autor:
Alina Tscherne, Enrico Mantel, Talar Boskani, Sylwia Budniak, Mandy Elschner, Antonio Fasanella, Siri L. Feruglio, Domenico Galante, Christian G. Giske, Roland Grunow, Judit Henczko, Christin Hinz, Wojciech Iwaniak, Daniela Jacob, Agnieszka Kedrak-Jablonska, Veronica K. Jensen, Tone B. Johansen, Gunnar Kahlmeter, Viviana Manzulli, Erika Matuschek, Falk Melzer, Maria S. Nuncio, Joseph Papaparaskevas, Ana Pelerito, Margrete Solheim, Susanne Thomann, Athanasios Tsakris, Tara Wahab, Marcin Weiner, Lothar Zoeller, Sabine Zange
Publikováno v:
Microorganisms, Vol 10, Iss 7, p 1470 (2022)
Brucellosis, mainly caused by Brucella (B.) melitensis, is associated with a risk of chronification and relapses. Antimicrobial susceptibility testing (AST) standards for B. melitensis are not available, and the agent is not yet listed in the EUCAST
Externí odkaz:
https://doaj.org/article/3292b027dd2240268b29626663aaa004