Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Alina Seidel"'
Autor:
Qingxing Wang, Sabrina Noettger, Qinya Xie, Chiara Pastorio, Alina Seidel, Janis A. Müller, Christoph Jung, Timo Jacob, Konstantin M. J. Sparrer, Fabian Zech, Frank Kirchhoff
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Utilization of human ACE2 allowed several bat coronaviruses (CoVs), including the causative agent of COVID-19, to infect humans directly or via intermediate hosts. However, the determinants of species-specific differences in ACE2 usage and t
Externí odkaz:
https://doaj.org/article/899254fb424e48cfa6a46c7aca5fb272
Autor:
Dominik Pflumm, Alina Seidel, Fabrice Klein, Rüdiger Groß, Lea Krutzke, Stefan Kochanek, Joris Kroschel, Jan Münch, Katja Stifter, Reinhold Schirmbeck
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
A multitude of alterations in the old immune system impair its functional integrity. Closely related, older individuals show, for example, a reduced responsiveness to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vaccines. However, sys
Externí odkaz:
https://doaj.org/article/1395366881924627908397826e673d79
Autor:
Emanuela D’Acunto, Alessia Muzi, Silvia Marchese, Lorena Donnici, Valerio Chiarini, Federica Bucci, Emiliano Pavoni, Fabiana Fosca Ferrara, Manuela Cappelletti, Roberto Arriga, Silvia Maria Serrao, Valentina Peluzzi, Eugenia Principato, Mirco Compagnone, Eleonora Pinto, Laura Luberto, Daniela Stoppoloni, Armin Lahm, Rüdiger Groß, Alina Seidel, Lukas Wettstein, Jan Münch, Andrew Goodhead, Judicael Parisot, Raffaele De Francesco, Gennaro Ciliberto, Emanuele Marra, Luigi Aurisicchio, Giuseppe Roscilli
Publikováno v:
Antibodies, Vol 13, Iss 1, p 5 (2024)
The COVID-19 pandemic, once a global crisis, is now largely under control, a testament to the extraordinary global efforts involving vaccination and public health measures. However, the relentless evolution of SARS-CoV-2, leading to the emergence of
Externí odkaz:
https://doaj.org/article/c7871d373abc48969226325b103c6a9c
Autor:
Eva-Maria Jacobsen, Dorit Fabricius, Magdalena Class, Fernando Topfstedt, Raquel Lorenzetti, Iga Janowska, Franziska Schmidt, Julian Staniek, Maria Zernickel, Thomas Stamminger, Andrea N. Dietz, Angela Zellmer, Manuel Hecht, Peter Rauch, Carmen Blum, Carolin Ludwig, Bernd Jahrsdörfer, Hubert Schrezenmeier, Maximilian Heeg, Benjamin Mayer, Alina Seidel, Rüdiger Groß, Jan Münch, Frank Kirchhoff, Sebastian F. N. Bode, Gudrun Strauss, Hanna Renk, Roland Elling, Maximillian Stich, Reinhard E. Voll, Burkhard Tönshof, Axel R. Franz, Philipp Henneke, Klaus-Michael Debatin, Marta Rizzi, Ales Janda
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Severity of SARS-CoV-2 infection is different in adults and children which involves the immune response. Here using a parent and children cohort with 4 month and 12 month sampling times, the authors show enhanced levels and increased breadth of anti-
Externí odkaz:
https://doaj.org/article/81ce609da88b45238e8d4a923e4304a2
Autor:
Alina Seidel, Simone Hoffmann, Bernd Jahrsdörfer, Sixten Körper, Carolin Ludwig, Christiane Vieweg, Dan Albers, Pascal von Maltitz, Rebecca Müller, Ramin Lotfi, Patrick Wuchter, Harald Klüter, Frank Kirchhoff, Michael Schmidt, Jan Münch, Hubert Schrezenmeier
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundRecent data on immune evasion of new SARS-CoV-2 variants raise concerns about the efficacy of antibody-based COVID-19 therapies. Therefore, in this study the in-vitro neutralization capacity against SARS-CoV-2 variant B.1 and the Omicron su
Externí odkaz:
https://doaj.org/article/421634f4916d4fde9d8b1c1537f0b244
Autor:
Alina Seidel, Eva-Maria Jacobsen, Dorit Fabricius, Magdalena Class, Maria Zernickel, Carmen Blum, Carina Conzelmann, Tatjana Weil, Rüdiger Groß, Sebastian F. N. Bode, Hanna Renk, Roland Elling, Maximillian Stich, Frank Kirchhoff, Klaus-Michael Debatin, Jan Münch, Aleš Janda
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
IntroductionDurability of immune protection against reinfection with SARS-CoV-2 remains enigmatic, especially in the pediatric population and in the context of immune-evading variants of concern. Obviously, this knowledge is required for measures to
Externí odkaz:
https://doaj.org/article/bc8842172d6a4f71844ef10e1613a2d4
Autor:
Hanna Renk, Alex Dulovic, Alina Seidel, Matthias Becker, Dorit Fabricius, Maria Zernickel, Daniel Junker, Rüdiger Groß, Janis Müller, Alexander Hilger, Sebastian F. N. Bode, Linus Fritsch, Pauline Frieh, Anneke Haddad, Tessa Görne, Jonathan Remppis, Tina Ganzemueller, Andrea Dietz, Daniela Huzly, Hartmut Hengel, Klaus Kaier, Susanne Weber, Eva-Maria Jacobsen, Philipp D. Kaiser, Bjoern Traenkle, Ulrich Rothbauer, Maximilian Stich, Burkhard Tönshoff, Georg F. Hoffmann, Barbara Müller, Carolin Ludwig, Bernd Jahrsdörfer, Hubert Schrezenmeier, Andreas Peter, Sebastian Hörber, Thomas Iftner, Jan Münch, Thomas Stamminger, Hans-Jürgen Groß, Martin Wolkewitz, Corinna Engel, Weimin Liu, Marta Rizzi, Beatrice H. Hahn, Philipp Henneke, Axel R. Franz, Klaus-Michael Debatin, Nicole Schneiderhan-Marra, Ales Janda, Roland Elling
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
In this prospective cohort study, authors follow 328 households in Germany with at least one confirmed SARS-CoV-2 infection and find that children are more likely to seroconvert without symptoms and have higher specific antibody levels that persist l
Externí odkaz:
https://doaj.org/article/af0bd9036d2c4e6cb0fbd39a1d97ce6a
Autor:
Alina Seidel, Michelle Zanoni, Rüdiger Groß, Daniela Krnavek, Sümeyye Erdemci-Evin, Pascal von Maltitz, Dan P. J. Albers, Carina Conzelmann, Sichen Liu, Tatjana Weil, Benjamin Mayer, Markus Hoffmann, Stefan Pöhlmann, Alexandra Beil, Joris Kroschel, Frank Kirchhoff, Jan Münch, Janis A. Müller
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
In light of the decreasing immune protection against symptomatic SARS-CoV-2 infection after initial vaccinations and the now dominant immune-evasive Omicron variants, ‘booster’ vaccinations are regularly performed to restore immune responses. Man
Externí odkaz:
https://doaj.org/article/ac9793b0bc7c48ab8e2e2d0c7a79653d
Autor:
Lukas Wettstein, Tatjana Weil, Carina Conzelmann, Janis A. Müller, Rüdiger Groß, Maximilian Hirschenberger, Alina Seidel, Susanne Klute, Fabian Zech, Caterina Prelli Bozzo, Nico Preising, Giorgio Fois, Robin Lochbaum, Philip Maximilian Knaff, Volker Mailänder, Ludger Ständker, Dietmar Rudolf Thal, Christian Schumann, Steffen Stenger, Alexander Kleger, Günter Lochnit, Benjamin Mayer, Yasser B. Ruiz-Blanco, Markus Hoffmann, Konstantin M. J. Sparrer, Stefan Pöhlmann, Elsa Sanchez-Garcia, Frank Kirchhoff, Manfred Frick, Jan Münch
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Here, via screening of a polypeptide library from bronchoalveolar lavage, the authors identify and characterize α1-antitrypsin (α1AT) as SARS-CoV-2 inhibitor and show that α1AT binds and inactivates the serine protease TMPRSS2, which enzymatically
Externí odkaz:
https://doaj.org/article/056726122e3545e6b5177624a1dc537a
Autor:
Rüdiger Groß, Michelle Zanoni, Alina Seidel, Carina Conzelmann, Andrea Gilg, Daniela Krnavek, Sümeyye Erdemci-Evin, Benjamin Mayer, Markus Hoffmann, Stefan Pöhlmann, Weimin Liu, Beatrice H. Hahn, Alexandra Beil, Joris Kroschel, Bernd Jahrsdörfer, Hubert Schrezenmeier, Frank Kirchhoff, Jan Münch, Janis A. Müller
Publikováno v:
EBioMedicine, Vol 75, Iss , Pp 103761- (2022)
Summary: Background: Heterologous COVID-19 vaccination regimens combining vector- and mRNA-based vaccines are already administered, but data on solicited adverse reactions, immunological responses and elicited protection are limited. Methods: To eval
Externí odkaz:
https://doaj.org/article/fcd33430a2d842e9bd5f10ff02995e22