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pro vyhledávání: '"Alina Schrimpf"'
Autor:
Alina Schrimpf, Olivia Knappe, Natalia Qvartskhava, Gereon Poschmann, Kai Stühler, Hans Jürgen Bidmon, Tom Luedde, Dieter Häussinger, Boris Görg
Publikováno v:
Analytical Biochemistry. 641:114548
Molecular alterations underlying cerebral impairment in hyperammonemic disorders such as in hepatic encephalopathy (HE) are only poorly understood. Using transcriptomics and proteomics on brains of mice with systemic hyperammonemia resulting from kno
Autor:
Elina Schütz, Boris Görg, Ayse Karababa, Hans J. Bidmon, Aygul K. Shafigullina, Mirco Castoldi, Alina Schrimpf, Dieter Häussinger, Martha Paluschinski
Publikováno v:
Journal of hepatology. 71(5)
Background & Aims Cerebral oxidative stress plays an important role in the pathogenesis of hepatic encephalopathy (HE), but the underlying mechanisms are incompletely understood. Herein, we analyzed a role of heme oxygenase (HO)1, iron and NADPH oxid