Výsledky vyhledávání - "Alina S, Bergshoeff"

Age-dependent pharmacokinetics of lamivudine in HIV-infected children

Autor: Hannah Green, Natella Rakhmanina, G. Verweel, R.A. de Groot, Hermione Lyall, Alina S. Bergshoeff, C.J.L. la Porte, Nico G. Hartwig, Diana M. Gibb, Steven J. Soldin, David M. Burger, C.P.W.G.M. Verwey-van Wissen

Publikováno v: Clinical Pharmacology and Therapeutics, 81, 517-20
Clinical Pharmacology and Therapeutics, 81, 4, pp. 517-20
Clinical Pharmacology & Therapeutics, 81(4), 517-520. Wiley-Blackwell

Contains fulltext : 52486.pdf (Publisher’s version ) (Closed access) The recommended dose of lamivudine in children is higher when compared with adults: 4 mg/kg vs approximately 2 mg/kg (150 mg) and administered twice a day. Limited data are availa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5170db0c7085ea6e30b0afd7927b3357
https://hdl.handle.net/2066/52486

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Increased dose of lopinavir/ritonavir compensates for efavirenz-induced drug-drug interaction in HIV-1-infected children

Autor: Tim Niehues, David M. Burger, Pieter L. A. Fraaij, Gwenda Verweel, Nico G. Hartwig, Ronald de Groot, Alina S. Bergshoeff, Jennifer Ndagijimana

Publikováno v: JAIDS : Journal of Acquired Immune Deficiency Syndromes, 39, 1, pp. 63-8
JAIDS : Journal of Acquired Immune Deficiency Syndromes, 39, 63-8
Jaids. Journal of Acquired Immune Deficiency Syndromes, 39(1), 63-68. Lippincott Williams & Wilkins

Contains fulltext : 48066.pdf (Publisher’s version ) (Closed access) BACKGROUND: Nucleoside reverse transcriptase inhibitor-sparing regimens have not yet been systematically evaluated in children. The nonnucleoside reverse transcriptase inhibitors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f046f6579ed4f27ab798dd076f51e2
https://doi.org/10.1097/01.qai.0000155203.89350.85

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Nelfinavir plasma concentrations are low during pregnancy

Autor: Mieke H. Godfried, David M. Burger, Joep M. A. Lange, Igor Schillevoort, Jan M. Prins, Kees Boer, Ferdinand W. N. M. Wit, Jeannine F. J. B. Nellen, Alina S. Bergshoeff

Publikováno v: Clinical Infectious Diseases, 39, 736-40
Clinical infectious diseases, 39(5), 736-740. Oxford University Press
Clinical Infectious Diseases, 39, 5, pp. 736-40

Contains fulltext : 58746.pdf (Publisher’s version ) (Closed access) Plasma nelfinavir concentration ratios (CRs) were calculated for all pregnant (n=27) and nonpregnant (n=48) human immunodeficiency virus type 1-infected women receiving the drug w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ff563a8da31570b484c5c973ad7598
https://doi.org/10.1086/422719

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Plasma concentrations of the HIV-protease inhibitor lopinavir are suboptimal in children aged 2 years and below

Autor: Gwenda, Verweel, David M, Burger, Nancy L, Sheehan, Alina S, Bergshoeff, Adilia, Warris, Linda C, van der Knaap, Gertjan, Driessen, Ronald, de Groot, Nico G, Hartwig

Publikováno v: Antiviral therapy. 12(4)

Lopinavir/ritonavir (LPV/r) has been licensed for the treatment of HIV-infected children6 months in the US and2 years in the EU. Limited LPV paediatric pharmacokinetic data are available. We studied LPV pharmacokinetics to determine whether the recom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::757e9cc1ea5f70cb525b652f7de94e26
https://pubmed.ncbi.nlm.nih.gov/17668553

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Plasma concentrations of the HIV-protease inhibitor lopinavir are suboptimal in children aged 2 years and below

Autor: Ronald de Groot, Nico G. Hartwig, Gwenda Verweel, Adilia Warris, David M. Burger, Alina S. Bergshoeff, Nancy L. Sheehan, Linda C Van Der Knaap, Gertjan J. Driessen

Publikováno v: Antiviral Therapy, 12, 4, pp. 453-8
Antiviral Therapy, 12, 453-8
Antiviral Therapy, 12(4), 453-458. International Medical Press Ltd

BackgroundLopinavir/ritonavir (LPV/r) has been licensed for the treatment of HIV-infected children >6 months in the US and >2 years in the EU. Limited LPV paediatric pharmacokinetic data are available. We studied LPV pharmacokinetics to determine whe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a97e71a89ea29cf6dcb0b31180300c42
https://hdl.handle.net/2066/52704

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Plasma pharmacokinetics of once- versus twice-daily lamivudine and abacavir: simplification of combination treatment in HIV-1-infected children (PENTA-13)

Autor: C. Verweij, L. Farrelly, Saye Khoo, David M. Burger, Hermione Lyall, V. Novelli, Alina S. Bergshoeff, Sarah V Walker, J. Flynn, M. Le Prevost, D M Gibb

Publikováno v: Antiviral Therapy, 10, 2, pp. 239-46
Antiviral Therapy, 10, 239-46

BackgroundThere are few data on plasma and intracellular pharmacokinetics (PK) of once-daily (q24h) nucleoside analogues in HIV-infected children.MethodsChildren aged 2–13 years receiving combination treatment containing lamivudine (3TC) (4 mg/kg)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485bb0655de80c30a91ee14947cc9e71
https://hdl.handle.net/2066/49182

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Pharmacokinetics and 24-week efficacy/safety of dual boosted saquinavir/lopinavir/ritonavir in nucleoside-pretreated children

Autor: Pope Kosalaraksa, Umaporn Siangphoe, Kiat Ruxrungtham, Andrew F. Hill, Chulapan Engchanil, Chitsanu Pancharoen, David M. Burger, Alina S. Bergshoeff, Jintanat Ananworanich

Publikováno v: Pediatric Infectious Disease Journal, 24, 10, pp. 874-9
Pediatric Infectious Disease Journal, 24, 874-9

Contains fulltext : 49117.pdf (Publisher’s version ) (Closed access) OBJECTIVE: To assess the pharmacokinetics and 24-week efficacy and safety of dual boosted saquinavir/lopinavir/ritonavir combination in children. DESIGN: Twenty reverse transcript

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057e0a3fef4eaad08d54146cb446d5c6
https://doi.org/10.1097/01.inf.0000180578.38584.da

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Plasma levels of zidovudine twice daily compared with three times daily in six HIV-1-infected children

Autor: Ronald de Groot, David M. Burger, Corrien Verweij, Annemarie M. C. van Rossum, Nico G. Hartwig, Alina S. Bergshoeff, Pieter L. A. Fraaij, Gwenda Verweel

Publikováno v: Journal of Antimicrobial Chemotherapy, 54, 1152-4
Journal of Antimicrobial Chemotherapy, 54(6), 1152-1154. Oxford University Press
Journal of Antimicrobial Chemotherapy, 54, 6, pp. 1152-4

Contains fulltext : 57984.pdf (Publisher’s version ) (Closed access) OBJECTIVES: Zidovudine is often administered every 12 h in HIV-infected children, but so far no pharmacokinetic data are available for the administration of this agent every 12 h.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa23bc8f4c9672cfcddc88493dafbad9
https://doi.org/10.1093/jac/dkh490

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Pharmacokinetics of indinavir combined with low-dose ritonavir in human immunodeficiency virus type 1-infected children

Autor: R. de Groot, A. M. C. van Rossum, David M. Burger, R. Y. Leavitt, Bach-Yen Nguyen, L. H. Wynne, G. Verweel, Pieter L. A. Fraaij, Alina S. Bergshoeff, Gregory A. Winchell

Publikováno v: Antimicrobial Agents & Chemotherapy, 48(5), 1904-1907. American Society for Microbiology
Antimicrobial Agents and Chemotherapy, 48, 1904-7
Antimicrobial Agents and Chemotherapy, 48, 5, pp. 1904-7

Contains fulltext : 58632.pdf (Publisher’s version ) (Closed access) So far, no pediatric doses for indinavir combined with ritonavir have been defined. This study evaluated the pharmacokinetics of 400 mg of indinavir/m(2) combined with 125 mg of r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc3670f7f53dbbb9c4b56b5d1d0bac8f
https://doi.org/10.1128/AAC.48.5.1904-1907.2004

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