Zobrazeno 1 - 2
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pro vyhledávání: '"Alina Russ"'
Autor:
Alina Russ, Sabine Wittmann, Yuta Tsukamoto, Alexandra Herrmann, Janina Deutschmann, Justine Lagisquet, Armin Ensser, Hiroki Kato, Thomas Gramberg
Publikováno v:
EMBO reports. 23
Methylation of the mRNA 5′ cap by cellular methyltransferases enables efficient translation and avoids recognition by innate immune factors. Coronaviruses encode viral 2′‐O‐methyltransferases to shield their RNA from host factors. Here, we ge
Autor:
Christian Krapp, Ben Berkhout, Matteo Bosso, Martin R. Jakobsen, Sabine Wittmann, Thomas Gramberg, Kasper L Jønsson, Daniel Sauter, Christina M. Stürzel, Dominik Hotter, Elisabeth Littwitz-Salomon, Yue Zheng, Alina Russ, Ulf Dittmer, Frank Kirchhoff, Vicente Planelles, Beatrice H. Hahn, Atze T. Das, Laura J. Martins
Publikováno v:
Cell Host Microbe
Cell host & microbe, 25(6), 858-872.e13. Cell Press
Hotter, D, Bosso, M, Jønsson, K L, Krapp, C, Stürzel, C M, Das, A, Littwitz-Salomon, E, Berkhout, B, Russ, A, Wittmann, S, Gramberg, T, Zheng, Y, Martins, L J, Planelles, V, Jakobsen, M R, Hahn, B H, Dittmer, U, Sauter, D & Kirchhoff, F 2019, ' IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation ', Cell Host & Microbe, vol. 25, no. 6, pp. 858-872.e13 . https://doi.org/10.1016/j.chom.2019.05.002
Cell host & microbe, 25(6), 858-872.e13. Cell Press
Hotter, D, Bosso, M, Jønsson, K L, Krapp, C, Stürzel, C M, Das, A, Littwitz-Salomon, E, Berkhout, B, Russ, A, Wittmann, S, Gramberg, T, Zheng, Y, Martins, L J, Planelles, V, Jakobsen, M R, Hahn, B H, Dittmer, U, Sauter, D & Kirchhoff, F 2019, ' IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation ', Cell Host & Microbe, vol. 25, no. 6, pp. 858-872.e13 . https://doi.org/10.1016/j.chom.2019.05.002
The interferon γ-inducible protein 16 (IFI16) is known as immune sensor of retroviral DNA intermediates. We show that IFI16 restricts HIV-1 independently of immune sensing by binding and inhibiting the host transcription factor Sp1 that drives viral