Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Alina Montero-Torres"'
Autor:
Alicia Gómez-Barrio, Maria Celeste Vega, Miriam Rolón, José Antonio Escario, Jorge Galvez, Cristina Fonseca-Berzal, Alina Montero-Torres, Yovani Marrero-Ponce, Vicente J. Arán
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Chagas disease chemotherapy, currently based on only two drugs, nifurtimox and benznidazole, is far from satisfactory and therefore the development of new antichagasic compounds remains an important goal. On the basis of antichagasic properties previ
Autor:
Enrique Pandolfi, Virginia Roldos, Celeste Vega, Viviana Heguaburu, Gloria Yaluff, Alicia Gómez-Barrio, Hector Nakayama, Maria Elena Ferreira, Antonieta Rojas de Arias, Yovanni Marrero-Ponce, Miriam Rolón, Luis Sanabria, Susana Torres, Fernando Trucco, Alina Montero-Torres
Publikováno v:
European Journal of Medicinal Chemistry. 43:1797-1807
The synthesis and potent antiprotozoal activity of 14-hydroxylunularin, a natural hydroxybibenzyl bryophyte constituent is reported. 14-hydroxylunularin was highly active in vitro assays against culture and intracellular forms of Leishmania spp. and
Autor:
Carmen Ochoa, Yovani Marrero-Ponce, Yanetsy Machado-Tugores, A.R. Martínez-Fernández, Rory N. García-Sánchez, Vicente J. Arán, Alina Montero-Torres, Juan José Nogal-Ruiz, Alfredo Meneses-Marcel, Francisco Torrens
Publikováno v:
European Journal of Medicinal Chemistry. 41:483-493
In order to explore the ability of non-stochastic quadratic indices to encode chemical information in antimalarials, four quantitative models for the discrimination of compounds having this property were generated and statistically compared. Accuraci
Autor:
A.R. Martínez-Fernández, Maria Gabriela Cabrera-Serra, Jan Tytgat, Norma Rivera, Facundo Pérez-Giménez, José E. Piñero, Roberto Chicharro, Ramón García-Domenech, Rory N. García-Sánchez, Miriam Rolón, Vicente J. Arán, Ricardo Mondragón, Atteneri López-Arencibia, Yovani Marrero-Ponce, Miriam A. Martins Alho, Jacob Lorenzo-Morales, Alina Montero-Torres, Stephen J. Barigye, Carmen M. Martín-Navarro, Froylán Ibarra-Velarde, Juan José Nogal, Maria Celeste Vega, Mónica Mondragón, Alicia Gómez-Barrio, José Antonio Escario, Alfredo Meneses-Marcel, Yanetsy Machado Tugores
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
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Protozoan parasites have been one of the most significant public health problems for centuries and several human infections caused by them have massive global impact. Most of the current drugs used to treat these illnesses have been used for decades
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a68fe42fda2b6e7b7182e6d06671a2
http://hdl.handle.net/10261/93642
http://hdl.handle.net/10261/93642
Autor:
Maria Celeste Vega, Ricardo Mondragón, Juan José Nogal, Miriam A. Martins Alho, Yanetsy Machado Tugores, A.R. Martínez-Fernández, Miriam Rolón, Vicente J. Arán, Alina Montero-Torres, Yovani Marrero-Ponce, Froylán Ibarra-Velarde, Rory N. García-Sánchez, Alicia Gómez-Barrio, José Antonio Escario, Mónica Mondragón, Alfredo Meneses-Marcel, Roberto Chicharro, Norma Rivera, Facundo Pérez-Giménez
Publikováno v:
Proceedings of The 12th International Electronic Conference on Synthetic Organic Chemistry.
Autor:
Alfredo Meneses-Marcel, Yovani Marrero-Ponce, Maria Celeste Vega, Vicente J. Arán, Francisco Torrens, Miriam Rolón, Alicia Gómez-Barrio, José Antonio Escario, Alina Montero-Torres, Juan José Nogal
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(7)
The antitrypanosomal activity of 10 already synthesized compounds was in silico predicted as well as in vitro and in vivo explored against Trypanosoma cruzi. For the computational study, an approach based on non-stochastic linear fingerprints to the
Autor:
C. A. Brandt, Karin Kirchgatter, Maité Iyarreta-Veitía, Carlos Romero-Zaldivar, Yovani Marrero-Ponce, Yanetsy Machado, Alina Montero-Torres, Priscilla E. Ávila
Publikováno v:
Proceedings of The 9th International Electronic Conference on Synthetic Organic Chemistry.
Malaria is one of the most significant public health concerns in many tropical and subtropical regions of the world, with 40% of the world population exposed to malaria-causing parasites. Increasing resistance of Plasmodium spp. to existing therapies
Autor:
Carlos Romero-Zaldivar, Maité Iyarreta-Veitía, Karin Kirchgatter, Priscilla E. Ávila, C. A. Brandt, Yanetsy Machado, Yovani Marrero-Ponce, Alina Montero-Torres
Publikováno v:
ChemInform. 36
Malaria has been one of the most significant public health problems for centuries. It affects many tropical and subtropical regions of the world. The increasing resistance of Plasmodium spp. to existing therapies has heightened alarms about malaria i
Autor:
Alfredo Meneses-Marcel, Juan José Nogal-Ruiz, Carmen Ochoa, Alina Montero-Torres, Yovani Marrero-Ponce, José Antonio Escario, Vicente J. Arán, A.R. Martínez-Fernández, Francisco Torrens, David Montero Pereira, Alicia Barrio, Yanetsy Machado-Tugores, Rory N. García Sánchez
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Computational approaches are developed to design or rationally select, from structural databases, new lead trichomonacidal compounds. First, a data set of 111 compounds was split (design) into training and predicting series using hierarchical and par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4610739a9038c7c480e9973d431f76ab
http://hdl.handle.net/10261/87256
http://hdl.handle.net/10261/87256
Autor:
Vicente J. Arán, Yovani Marrero-Ponce, Alfredo Meneses-Marcel, A.R. Martínez-Fernández, Rory N. García Sánchez, Carmen Ochoa, Juan José Nogal-Ruiz, José Antonio Escario, Yanetsy Machado-Tugores, Alina Montero-Torres, David Montero Pereira
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
A computational (virtual) screening test to identify potential trichomonacidals has been developed. Molecular structures of trichomonacidal and non-trichomonacidal drugs were represented using stochastic and non-stochastic atom-based quadratic indice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384797976d562b2765492c8a3b6084ac
http://hdl.handle.net/10261/87339
http://hdl.handle.net/10261/87339