Comparative proteomics reveals novel components at the plasma membrane of differentiated HepaRG cells and different distribution in hepatocyte- and biliary-like cells.

Autor: Catalina Petrareanu, Alina Macovei, Izabela Sokolowska, Alisa G Woods, Catalin Lazar, Gabriel L Radu, Costel C Darie, Norica Branza-Nichita

Publikováno v: PLoS ONE, Vol 8, Iss 8, p e71859 (2013)

Hepatitis B virus (HBV) is a human pathogen causing severe liver disease and eventually death. Despite important progress in deciphering HBV internalization, the early virus-cell interactions leading to infection are not known. HepaRG is a human bipo

Externí odkaz: https://doaj.org/article/d3de11f4d1504535a13cb5b295f12b4c

Results of a prospective dose intensity and neutropenia prophylaxis evaluation programme (DIEPP) in cancer patients at risk of febrile neutropenia due to myelosuppressive chemotherapy

Autor: Alina Macovei, Lidia Popławska, Martin Safanda, Doru Ghizdavescu, Jana Benkovicova, Radosław Mądry, Tibor Csőszi, Christine Jaeger, Iveta Frkanova, Georgi Mihaylov, Ferdinand Haslbauer, Daniela Niepel, Christine Staudigl

Publikováno v: Wiener Klinische Wochenschrift

Summary Objective To describe the incidence of febrile neutropenia (FN) and use of pegfilgrastim in cancer patients with high overall risk of FN and to investigate the relationship between granulocyte-colony stimulating factor (G-CSF) guideline adher

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491bed00a92df9e86a3f8a9ca447b203
https://doi.org/10.1007/s00508-015-0917-1

Azo-polysiloxanes as new supports for cell cultures

Autor: Alina Raicu, Cristina Paius, Alina Macovei, Ioana Moleavin, Norica Branza-Nichita, Licinio Rocha, Matthieu Hamel, Nicolae Hurduc

Publikováno v: Materials Science and Engineering: C
Materials Science and Engineering: C, Elsevier, 2013, 33 (4), pp.2440-2445. ⟨10.1016/j.msec.2013.01.012⟩
Materials Science and Engineering: C, 2013, 33 (4), pp.2440-2445. ⟨10.1016/j.msec.2013.01.012⟩

International audience; The paper introduces a new class of materials with azo-polysiloxanic structure bearing the property to generate nano-structured surfaces by laser irradiation. The ability to modulate the optical response of the film, through a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed21b2db81a4be7f4a2c9cbc46a7665
https://doi.org/10.1016/j.msec.2013.01.012

Characterization of the anti-HBV activity of HLP1-23, a human lactoferrin-derived peptide

Autor: Costel C. Darie, Norica Branza-Nichita, Anca Roseanu, Paula E. Florian, Robert W. Evans, Adina L. Milac, Izabela Sokolowska, Alina Macovei, Catalin Lazar

Publikováno v: Journal of Medical Virology. 85:780-788

Lactoferrin (Lf) was shown to exhibit its antiviral activity at an early phase of viral infection and a mechanism whereby the protein interacts with host cell surface molecules has been suggested. In this study, human Lf (HLf) and seven HLf-derived s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37dabadf55f0b54fc55b05b92dbd87de
https://doi.org/10.1002/jmv.23549

Endocytosis and trafficking of human lactoferrin in macrophage-like human THP-1 cells1This article is part of a Special Issue entitled Lactoferrin and has undergone the Journal’s usual peer review process

Autor: Alina Macovei, Norica Nichita, Inger Mattsby-Baltzer, Anca Roseanu, Paula E. Florian, Livia Elena Sima

Publikováno v: Biochemistry and Cell Biology. 90:449-455

Different cell types have been reported to internalize lactoferrin (Lf) by specific or nonspecific receptors. Our studies focused on the endocytic pathway of human Lf in macrophage-like THP-1 cells. Lactoferrin was found to be internalized by THP-1 c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e4bea83f40729004948fe99d58c7f067
https://doi.org/10.1139/o11-090