Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Alina M Hamilton"'
Autor:
Alina M. Hamilton, Andrea Walens, Sarah C. Van Alsten, Linnea T. Olsson, Joseph Nsonwu-Farley, Xiaohua Gao, Erin L. Kirk, Charles M. Perou, Lisa A. Carey, Melissa A. Troester, Yara Abdou
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Purpose Survivin/BIRC5 is a proliferation marker that is associated with poor prognosis in breast cancer and an attractive therapeutic target. However, BIRC5 has not been well studied among racially diverse populations where aggressive breas
Externí odkaz:
https://doaj.org/article/27b60ce2e45d4cbb9f8f5a40b8cba4bf
Autor:
Amber N. Hurson, Mustapha Abubakar, Alina M. Hamilton, Kathleen Conway, Katherine A. Hoadley, Michael I. Love, Andrew F. Olshan, Charles M. Perou, Montserrat Garcia-Closas, Melissa A. Troester
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract TP53 and estrogen receptor (ER) are essential in breast cancer development and progression, but TP53 status (by DNA sequencing or protein expression) has been inconsistently associated with survival. We evaluated whether RNA-based TP53 class
Externí odkaz:
https://doaj.org/article/529696f68a5e470a94d527f453ee537a
Autor:
Gieira S. Jones, Katherine A. Hoadley, Linnea T. Olsson, Alina M. Hamilton, Arjun Bhattacharya, Erin L. Kirk, Heather J. Tipaldos, Jodie M. Fleming, Michael I. Love, Hazel B. Nichols, Andrew F. Olshan, Melissa A. Troester
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-10 (2021)
Abstract Background African American women have the highest risk of breast cancer mortality compared to other racial groups. Differences in tumor characteristics have been implicated as a possible cause; however, the tumor microenvironment may also c
Externí odkaz:
https://doaj.org/article/1797c6c1ed634f91bcf484265b5f3f6e
Autor:
Alina M. Hamilton, Sarah C. Van Alsten, Xiaohua Gao, Joseph Nsonwu-Farley, Benjamin C. Calhoun, Michael I. Love, Melissa A. Troester, Katherine A. Hoadley
Publikováno v:
Cancer Research Communications. 3:12-20
Markers of genomic instability, including TP53 status and homologous recombination deficiency (HRD), are candidate biomarkers of immunogenicity and immune-mediated survival, but little is known about the distribution of these markers in large, popula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e630520bb1c17899ddf22f3d7324c2d2
https://doi.org/10.1158/2767-9764.crc-22-0267
https://doi.org/10.1158/2767-9764.crc-22-0267
Autor:
Linnea T. Olsson, Andrea Walens, Alina M. Hamilton, Halei C. Benefield, Jodie M. Fleming, Lisa A. Carey, Stephen D. Hursting, Kevin P. Williams, Melissa A. Troester
Publikováno v:
Cancer Epidemiol Biomarkers Prev
Background: Obese women have higher risk of aggressive breast tumors and distant metastasis. However, obesity has rarely been assessed in association with metastasis in diverse populations. Methods: In the Carolina Breast Cancer Study Phase 3 (2008
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5416c8b2588444c3f3c226c2c9e5823a
https://doi.org/10.1158/1055-9965.epi-22-0013
https://doi.org/10.1158/1055-9965.epi-22-0013
Autor:
Melissa A. Troester, Katherine A. Hoadley, Cyrus Vaziri, Charles M. Perou, Gaorav P. Gupta, Michael I. Love, Erin L. Kirk, Alina M. Hamilton, Xiaohua Gao, Alex Lockhart, Markia A. Smith, Linnea T. Olsson, Sarah C. Van Alsten, Andrea Walens
Background:Aberrant expression of DNA repair pathways such as homologous recombination (HR) can lead to DNA repair imbalance, genomic instability, and altered chemotherapy response. DNA repair imbalance may predict prognosis, but variation in DNA rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26082be2ddd4e39d8e04cca6b3b9f150
https://doi.org/10.1158/1055-9965.c.6660312.v1
https://doi.org/10.1158/1055-9965.c.6660312.v1
Autor:
Melissa A. Troester, Katherine A. Hoadley, Cyrus Vaziri, Charles M. Perou, Gaorav P. Gupta, Michael I. Love, Erin L. Kirk, Alina M. Hamilton, Xiaohua Gao, Alex Lockhart, Markia A. Smith, Linnea T. Olsson, Sarah C. Van Alsten, Andrea Walens
Supplementary Figure from RNA-Based Classification of Homologous Recombination Deficiency in Racially Diverse Patients with Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04cd3e65fc8112cd41e42cf4195fbcb1
https://doi.org/10.1158/1055-9965.23099349.v1
https://doi.org/10.1158/1055-9965.23099349.v1
Autor:
Katherine A. Hoadley, Melissa A. Troester, Michael I. Love, Benjamin C. Calhoun, Joseph Nsonwu-Farley, Xiaohua Gao, Sarah C. Van Alsten, Alina M. Hamilton
Supplemental figure 2 displays unadjusted adaptive and innate scores according TP53, HRD and PD-L1 status, stratified by estrogen receptor status.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07202e40aec25e9ce0b276ba374c175b
https://doi.org/10.1158/2767-9764.22546494
https://doi.org/10.1158/2767-9764.22546494
Autor:
Katherine A. Hoadley, Melissa A. Troester, Michael I. Love, Benjamin C. Calhoun, Joseph Nsonwu-Farley, Xiaohua Gao, Sarah C. Van Alsten, Alina M. Hamilton
Markers of genomic instability, including TP53 status and homologous recombination deficiency (HRD), are candidate biomarkers of immunogenicity and immune-mediated survival, but little is known about the distribution of these markers in large, popula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546da8417ccebc5ba6809ee17b04350e
https://doi.org/10.1158/2767-9764.c.6551187
https://doi.org/10.1158/2767-9764.c.6551187
Autor:
Katherine A. Hoadley, Melissa A. Troester, Michael I. Love, Benjamin C. Calhoun, Joseph Nsonwu-Farley, Xiaohua Gao, Sarah C. Van Alsten, Alina M. Hamilton
Supplemental table 3 shows five-year recurrence hazard ratios for immune classes among ER-negative and ER-positive cases in CBCS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81421cf796fd511ecb94b6e17ce69a9c
https://doi.org/10.1158/2767-9764.22546485.v1
https://doi.org/10.1158/2767-9764.22546485.v1