Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alina Heyfets"'
Autor:
Pinhas Gonen, Alina Heyfets, Levana Sherman, Tatiana Kniazhanski, Eliezer Flescher, Anna Jackman
Publikováno v:
Cancer Letters. 271:34-46
In the present study the effectiveness of methyl jasmonate (MJ) against cervical cancer cell lines was investigated. We show that MJ is cytotoxic to a range of cervical cancer lines including SiHa, CaSki and HeLa that carry human papillomavirus (HPV)
Publikováno v:
British Journal of Pharmacology. 150:738-749
Background and purpose: No current treatment reliably affects the course of metastatic melanoma. Consequently, novel approaches to the control of metastasis are actively sought. The overall goal of the present study was to identify new anti-metastati
Publikováno v:
Journal of Bioenergetics and Biomembranes. 39:51-57
Jasmonates are plant stress hormones that induce suppression of proliferation and death in cancer cells, while being selectively inactive towards non-transformed cells. Jasmonates can overcome apoptotic blocks and exert cytotoxic effects on drug-resi
Publikováno v:
Cancer Research. 65:1984-1993
We reported previously that jasmonates can kill human cancer cells. Many chemotherapeutic drugs induce mitochondrial membrane permeability transition, membrane depolarization, osmotic swelling, and release of cytochrome c, involving the opening of th
Autor:
Gabriele Schramm, Michael J. Doenhoff, Daniel Gold, Jacob Golenser, Judith H. Waknine-Grinberg, Alina Heyfets, Eliezer Flescher, Ariel Ohayon, Helmut L. Haas
Publikováno v:
Malaria Journal, Vol 9, Iss 1, p 5 (2010)
Malaria Journal
Malaria Journal
BackgroundPlasmodiumandSchistosomaare two of the most common parasites in sub-tropical areas. Deregulation of the immune response toPlasmodium falciparum, characterized by a Th1 response, leads to cerebral malaria (CM), while a Th2 response accompani
Autor:
Tsafrir Bravman, Ariel G. Notcovich, Adrian Israelson, Z. Zaslavsky, Eliezer Flescher, Vered Bronner, Natalia Goldin, Laetitia Arzoine, Alina Heyfets, Varda Shoshan-Barmatz
Publikováno v:
Oncogene. 27(34)
Cellular bio-energetic metabolism and mitochondria are recognized as potential targets for anticancer agents, due to the numerous relevant peculiarities cancer cells exhibit. Jasmonates are anticancer agents that interact directly with mitochondria.
Autor:
Eliezer Flescher, Alina Heyfets
Publikováno v:
Cancer letters. 250(2)
The anti-cancer agent methyl jasmonate (MJ) acts in vitro and in vivo against various cancer cell lines, as well as leukemic cells from chronic lymphocytic leukemia (CLL) patients. Given the importance of multi-agent combinations in cancer chemothera
Publikováno v:
Immunology letters. 80(3)
Immunoglobulin idiotypes (Id) of malignant B lymphocytes and plasma cells are tumor-specific antigens that were extensively used in immunotherapy studies. The effector mechanisms, involved in resistance to tumor following Id vaccination, are a contro