Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Alina Grzanka"'
Autor:
Klaudia Piekarska, Klaudia Bonowicz, Alina Grzanka, Łukasz M. Jaworski, Russel J. Reiter, Andrzej T. Slominski, Kerstin Steinbrink, Konrad Kleszczyński, Maciej Gagat
Publikováno v:
Metabolites, Vol 13, Iss 4, p 575 (2023)
The immune system, unlike other systems, must be flexible and able to “adapt” to fully cope with lurking dangers. The transition from intracorporeal balance to homeostasis disruption is associated with activation of inflammatory signaling pathway
Externí odkaz:
https://doaj.org/article/72de0112d94142faa19a8298ed80284b
Autor:
Klaudia Bonowicz, Klaudia Mikołajczyk, Inaz Faisal, Murtaz Qamar, Kerstin Steinbrink, Konrad Kleszczyński, Alina Grzanka, Maciej Gagat
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15335 (2022)
Extracellular vesicles (EVs) serve as central mediators in communication between tumor and non-tumor cells. These interactions are largely dependent on the function of the endothelial barrier and the set of receptors present on its surface, as endoth
Externí odkaz:
https://doaj.org/article/a0e1be4b913740e5a02cd07673a83e4d
Autor:
Maciej Gagat, Wioletta Zielińska, Klaudia Mikołajczyk, Jan Zabrzyński, Adrian Krajewski, Anna Klimaszewska-Wiśniewska, Dariusz Grzanka, Alina Grzanka
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Tumor necrosis factor α (TNFα) is one of the most important proinflammatory cytokines, which affects many processes associated with the growth and characteristics of endothelial, smooth muscle, and immune system cells. However, there is no correlat
Externí odkaz:
https://doaj.org/article/a2b4d10d4f90471cbe490e21668c84fa
Autor:
Klaudia Mikołajczyk, Dominika Spyt, Wioletta Zielińska, Agnieszka Żuryń, Inaz Faisal, Murtaz Qamar, Piotr Świniarski, Alina Grzanka, Maciej Gagat
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 13157 (2021)
Homeostasis is a fundamental property of biological systems consisting of the ability to maintain a dynamic balance of the environment of biochemical processes. The action of endogenous and exogenous factors can lead to internal balance disorder, whi
Externí odkaz:
https://doaj.org/article/436768bf5de64b4d9ec7475b4512ce09
Autor:
Magdalena Izdebska, Wioletta Zielińska, Adrian Krajewski, Marta Hałas-Wiśniewska, Klaudia Mikołajczyk, Maciej Gagat, Alina Grzanka
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 12783 (2021)
Metastasis is one of the most urgent issues in breast cancer patients. One of the factors necessary in the migration process is the remodeling of the extracellular matrix (ECM). Metalloproteinases (MMPs) can break down the elements of the ECM, which
Externí odkaz:
https://doaj.org/article/4610ce1282ea4028a7518e55c6643386
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7635 (2021)
The transient receptor potential (TRP) melastatin-like subfamily member 2 (TRPM2) is a non-selective calcium-permeable cation channel. It is expressed by many mammalian tissues, including bone marrow, spleen, lungs, heart, liver, neutrophils, and end
Externí odkaz:
https://doaj.org/article/269c86ed56254f0bbdd5f9812d66d4f4
Autor:
Anna Klimaszewska-Wiśniewska, Izabela Neska-Długosz, Karolina Buchholz, Justyna Durślewicz, Dariusz Grzanka, Anna Kasperska, Paulina Antosik, Jan Zabrzyński, Alina Grzanka, Maciej Gagat
Publikováno v:
Cancers, Vol 13, Iss 12, p 3017 (2021)
Available biomarkers for pancreatic adenocarcinoma (PAC) are inadequate to guide individual patient prognosis or therapy. Therefore, herein we aimed to verify the hypothesis that differences in the expression of KIF11 and KIF14, i.e., molecular motor
Externí odkaz:
https://doaj.org/article/014fa12f9f4c46209edc770ac3b8319e
Publikováno v:
Applied Sciences, Vol 11, Iss 5, p 2320 (2021)
Cyclins belong to a group of proteins that are cyclically produced and destructed in a cell. Cyclins are a family of proteins that are a key component of the cell cycle regulating system, which level of expression depends on the phase of the cycle. C
Externí odkaz:
https://doaj.org/article/c124f71ca7454cfaadd0850c20d5c367
Autor:
Anna Klimaszewska-Wiśniewska, Karolina Buchholz, Izabela Neska-Długosz, Justyna Durślewicz, Dariusz Grzanka, Jan Zabrzyński, Paulina Sopońska, Alina Grzanka, Maciej Gagat
Publikováno v:
Cancers, Vol 13, Iss 4, p 859 (2021)
In the present study, we aimed to assess the selected components of cell cycle machinery, checkpoint, DNA repair, and synthesis, namely RRM2, cyclin F, and SPDL1 in pancreatic adenocarcinomas (PAC) by in-house immunohistochemistry (IHC) and bioinform
Externí odkaz:
https://doaj.org/article/6f8a4175cd444020af2ef2b7d12ba819
Publikováno v:
Applied Sciences, Vol 11, Iss 5, p 1997 (2021)
Cell-penetrating peptides (CPPs), due to their effectiveness and low cytotoxicity, are of increasing interest in the context of the transport of macromolecules to the cells. The simplest and safest method seems to be the non-covalent binding of CPP a
Externí odkaz:
https://doaj.org/article/aca3dc79f1ff4bebadfcd82983371061