Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Alina D. Peshkova"'
Autor:
Christian Michael, Francesco Pancaldi, Samuel Britton, Oleg V. Kim, Alina D. Peshkova, Khoi Vo, Zhiliang Xu, Rustem I. Litvinov, John W. Weisel, Mark Alber
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract While blood clot formation has been relatively well studied, little is known about the mechanisms underlying the subsequent structural and mechanical clot remodeling called contraction or retraction. Impairment of the clot contraction proces
Externí odkaz:
https://doaj.org/article/66f585ef44854295b748b4e146d8d9c7
Autor:
Svetlana I. Safiullina, Natalia G. Evtugina, Izabella A. Andrianova, Rafael R. Khismatullin, Olga A. Kravtsova, Alina I. Khabirova, Chandrasekaran Nagaswami, Amina G. Daminova, Alina D. Peshkova, Rustem I. Litvinov, John W. Weisel
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Mutations in the MYH9 gene result in macrothrombocytopenia often associated with hemorrhages. Here, we studied the function and structure of platelets in three family members with a heterozygous mutation R1933X in the MYH9 gene, characterist
Externí odkaz:
https://doaj.org/article/528acacafb014a03a484f79693585463
Autor:
Natalia G. Evtugina, Svetlana S. Sannikova, Alina D. Peshkova, Svetlana I. Safiullina, Izabella A. Andrianova, Gulzada R. Tarasova, Alina I. Khabirova, Aleksandr G. Rumyantsev, Fazoil I. Ataullakhanov, Rustem I. Litvinov
Publikováno v:
Терапевтический архив, Vol 93, Iss 11, Pp 1255-1263 (2021)
Aim. To study the relationship of hemostatic disorders with inflammation and estimate their role in the course and outcomes of COVID-19. Materials and methods. We examined 215 consecutive patients with moderate and severe forms of acute COVID-19.
Externí odkaz:
https://doaj.org/article/03448ecf23d2443caf8f2b7608a32d5e
Autor:
Rustem I. Litvinov, Natalia G. Evtugina, Alina D. Peshkova, Svetlana I. Safiullina, Izabella A. Andrianova, Alina I. Khabirova, Chandrasekaran Nagaswami, Rafael R. Khismatullin, Svetlana S. Sannikova, John W. Weisel
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract To reveal if coagulopathies relate to the course of COVID-19, we examined 255 patients with moderate and severe COVID-19, receiving anticoagulants and immunosuppressive drugs. Coagulopathy manifested predominantly as hypercoagulability that
Externí odkaz:
https://doaj.org/article/036bc870feca4d6084489ea709a4889d
Autor:
Irina N. Chernysh, Chandrasekaran Nagaswami, Sofia Kosolapova, Alina D. Peshkova, Adam Cuker, Douglas B. Cines, Carolyn L. Cambor, Rustem I. Litvinov, John W. Weisel
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Although arterial and venous thromboembolic disorders are among the most frequent causes of mortality and morbidity, there has been little description of how the composition of thrombi and emboli depends on their vascular origin and age. We
Externí odkaz:
https://doaj.org/article/12086ecd9aa2460989bafb505ae629db
Chronic Immune Platelet Activation Is Followed by Platelet Refractoriness and Impaired Contractility
Autor:
Izabella A. Andrianova, Alina I. Khabirova, Anastasia A. Ponomareva, Alina D. Peshkova, Natalia G. Evtugina, Giang Le Minh, Timur B. Sibgatullin, John W. Weisel, Rustem I. Litvinov
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7336 (2022)
Autoimmune diseases, including systemic lupus erythematosus (SLE), have a high risk of thrombotic and hemorrhagic complications associated with altered platelet functionality. We studied platelets from the blood of SLE patients and their reactivity.
Externí odkaz:
https://doaj.org/article/5513fa5833de4845a5569ed65cfecf1c
Autor:
Rustem I. Litvinov, Alina D. Peshkova, Giang Le Minh, Nail N. Khaertdinov, Natalia G. Evtugina, Guzel F. Sitdikova, John W. Weisel
Publikováno v:
Metabolites, Vol 11, Iss 6, p 354 (2021)
Hyperhomocysteinemia (HHcy) is associated with thrombosis, but the mechanistic links between them are not understood. We studied effects of homocysteine (Hcy) on clot contraction in vitro and in a rat model of HHcy. Incubation of blood with exogenous
Externí odkaz:
https://doaj.org/article/1449fdd803f443fea97061930334b8a3
Autor:
Alina D. Peshkova, Giang Le Minh, Valerie Tutwiler, Izabella A. Andrianova, John W. Weisel, Rustem I. Litvinov
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Platelet-driven reduction in blood clot volume (clot contraction or retraction) has been implicated to play a role in hemostasis and thrombosis. Although these processes are often linked with inflammation, the role of inflammatory cells in c
Externí odkaz:
https://doaj.org/article/45047cfebe4440d8956266fb01d4ab35
Autor:
Oleg V. Kim, Tatiana A. Nevzorova, Elmira R. Mordakhanova, Anastasia A. Ponomareva, Izabella A. Andrianova, Giang Le Minh, Amina G. Daminova, Alina D. Peshkova, Mark S. Alber, Olga Vagin, Rustem I. Litvinov, John W. Weisel
Publikováno v:
Haematologica, Vol 104, Iss 9 (2019)
Platelets play a key role in the formation of hemostatic clots and obstructive thrombi as well as in other biological processes. In response to physiological stimulants, including thrombin, platelets change shape, express adhesive molecules, aggregat
Externí odkaz:
https://doaj.org/article/1d448e29d9eb438b86d5e74877ee1ebb
Autor:
Alina D. Peshkova, Tatiana A. Evdokimova, Timur B. Sibgatullin, Fazoil I. Ataullakhanov, Rustem I. Litvinov, John W. Weisel
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9434 (2020)
Rheumatoid arthritis (RA) is an autoimmune disease associated with thrombotic complications. To elucidate pathogenic mechanisms, hemostatic disorders in RA were correlated with other laboratory and clinical manifestations. Hemostasis was assessed usi
Externí odkaz:
https://doaj.org/article/8f80375dde0a4014b01929da404b84ac