Dynamic personalized risk prediction in chronic heart failure patients: a longitudinal, clinical investigation of 92 biomarkers (Bio-SHiFT study)

Autor: Dominika Klimczak-Tomaniak, Marie de Bakker, Elke Bouwens, K. Martijn Akkerhuis, Sara Baart, Dimitris Rizopoulos, Henk Mouthaan, Jan van Ramshorst, Tjeerd Germans, Alina Constantinescu, Olivier Manintveld, Victor Umans, Eric Boersma, Isabella Kardys

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)

Abstract The aim of our observational study was to derive a small set out of 92 repeatedly measured biomarkers with optimal predictive capacity for adverse clinical events in heart failure, which could be used for dynamic, individual risk assessment

Externí odkaz: https://doaj.org/article/9bff43d637134a2ea782a613c9c9c664

Neuro-fuzzy concepts applied for planning of the cereal crops: applications to the maize hybrids growing in a Romanian region

Autor: Alina Constantinescu

Publikováno v: Journal of Biological Dynamics, Vol 11, Iss 1, Pp 1-7 (2017)

The aim of our study is to improve the crop planning procedures using neuro-fuzzy concepts. In this paper we design a neuro-fuzzy procedure that offers the suitable maize hybrid, from a set of preferred hybrids, which must be organically farmed in th

Externí odkaz: https://doaj.org/article/9ddde4cb0699488cbf38b0f1b69d5eae

The Influence of the Motivational Factors on Work Performance

Autor: Alina Constantinescu, Ion Stegăroiu

Publikováno v: Postmodern Openings. 14:26-45

The employee motivation at the organizational level is naturally quantified in achieving performance goals. In this paper are studied the motivational factors from the perspective of employee work performance reflected, vertically, in the organizatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::82fe2b476221ce6106759ae037db33fc
https://doi.org/10.18662/po/14.1/602

Long-Term Outcome of Implantable Cardioverter-Defibrillators Therapy in Noncompaction Cardiomyopathy Compared with Dilated and Hypertrophic Cardiomyopathy

Autor: Emrah Kaya, Martijn Otten, Dominic A.M.J. Theuns, Kevin M. Veen, Sing-Chien Yap, Arend Schinkel, Alina Constantinescu, Michelle Michels, Olivier C. Manintveld, Tamas Szili-Torok, Kadir Caliskan

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a1fb5f47cf7d2273c08e12af2c6eccf9
https://doi.org/10.2139/ssrn.4129753

Lamin A/C-Related Cardiac Disease Late Onset With a Variable and Mild Phenotype in a Large Cohort of Patients With the Lamin A/C p.(Arg331Gln) Founder Mutation

Autor: Carlo Marcelis, Emmelien Aten, Arthur A.M. Wilde, Peter C. van den Akker, Jos L. V. Broers, Joeri A. Jansweijer, Karin Y. van Spaendonck-Zwarts, Rogier A. Oldenburg, Paul G.A. Volders, Aryan Vink, Edgar T. Hoorntje, Maarten P. van den Berg, Florence H J van Tienen, Jasper J. van der Smagt, Ilse A. E. Bollen, Jolanda van der Velden, Daniela Q.C.M. Barge-Schaapveld, Anthonie J. van Essen, Eric A. M. Hennekam, Alina Constantinescu, Arthur van den Wijngaard, J. Peter van Tintelen, Gerard J. te Meerman, Marianne Bootsma, Jan D. H. Jongbloed

Publikováno v: Circulation. Cardiovascular Genetics, 10, 4, pp. UNSP e001631-UNSP e001631
Circulation-Cardiovascular Genetics, 10(4):001631. LIPPINCOTT WILLIAMS & WILKINS
Circulation-Cardiovascular genetics, 10(4). Lippincott Williams and Wilkins
Circulation. Cardiovascular Genetics, 10, UNSP e001631-UNSP e001631
Circulation : Cardiovascular Genetics, 10(4):001631. LIPPINCOTT WILLIAMS & WILKINS
Circulation-cardiovascular genetics, 10(4):e001631. Lippincott Williams and Wilkins
Hoorntje, E T, Bollen, I A, Barge-Schaapveld, D Q, van Tienen, F H J, te Meerman, G J, Jansweijer, J A, van Essen, A J, Volders, P G, Constantinescu, A A, van den Akker, P C, van Spaendonck-Zwarts, K Y, Oldenburg, R A, Marcelis, C L, van der Smagt, J J, Hennekam, E A, Vink, A, Bootsma, M, Aten, E, Wilde, A A M, van den Wijngaard, A, Broers, J L, Jongbloed, J D, van der Velden, J, van den Berg, M P & van Tintelen, J P 2017, ' Lamin A/C-Related Cardiac Disease Late Onset With a Variable and Mild Phenotype in a Large Cohort of Patients With the Lamin A/C p.(Arg331Gln) Founder Mutation ', Circulation-cardiovascular genetics, vol. 10, no. 4, e001631 . https://doi.org/10.1161/CIRCGENETICS.116.001631
Circulation. Cardiovascular genetics, 10(4):e001631. Lippincott Williams and Wilkins
Circulation: Cardiovascular Genetics, 10(4)
Circulation-cardiovascular genetics, 10(4):UNSP e001631. Lippincott Williams & Wilkins

Background— Interpretation of missense variants can be especially difficult when the variant is also found in control populations. This is what we encountered for the LMNA c.992G>A (p.(Arg331Gln)) variant. Therefore, to evaluate the effect of this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f58eef0be6d324744d52cdf66058e46
https://doi.org/10.1161/circgenetics.116.001631