Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Alina Bora"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9583 (2023)
To facilitate the identification of novel MAO-B inhibitors, we elaborated a consolidated computational approach, including a pharmacophoric atom-based 3D quantitative structure–activity relationship (QSAR) model, activity cliffs, fingerprint, and m
Externí odkaz:
https://doaj.org/article/e266b7c369fc41efabcafaf5be22f9c3
Autor:
Luminita Crisan, Alina Bora
Publikováno v:
Life, Vol 11, Iss 7, p 722 (2021)
The human immunodeficiency virus type 1 (HIV-1), one of the leading causes of infectious death globally, generates severe damages to people’s immune systems and makes them susceptible to serious diseases. To date, there are no drugs that completely
Externí odkaz:
https://doaj.org/article/6fdd9ba0c0a3480dab9633bc7dfec7c0
Autor:
Simona Funar-Timofei, Alina Bora
Publikováno v:
Proceedings, Vol 9, Iss 1, p 18 (2019)
This paper presents a Quantitative Structure-Activity Relationship (QSAR) study of a series of 24 dihydropyrrole-fused and phenylazo neonicotinoid derivatives, with insecticidal activity tested against Cowpea aphids (Aphis craccivora). In this regard
Externí odkaz:
https://doaj.org/article/dbca9857962d4ff281d0b529c04a471d
Autor:
Sorin Avram, Thomas B Wilson, Ramona Curpan, Liliana Halip, Ana Borota, Alina Bora, Cristian G Bologa, Jayme Holmes, Jeffrey Knockel, Jeremy J Yang, Tudor I Oprea
Publikováno v:
Nucleic Acids Research. 51:D1276-D1287
DrugCentral monitors new drug approvals and standardizes drug information. The current update contains 285 drugs (131 for human use). New additions include: (i) the integration of veterinary drugs (154 for animal use only), (ii) the addition of 66 do
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9583
To facilitate the identification of novel MAO-B inhibitors, we elaborated a consolidated computational approach, including a pharmacophoric atom-based 3D quantitative structure–activity relationship (QSAR) model, activity cliffs, fingerprint, and m
Autor:
Agata N. Makar, Alina Boraman, Peter Mosen, Joanne E. Simpson, Jair Marques, Tim Michelberger, Stuart Aitken, Ann P. Wheeler, Dominic Winter, Alex von Kriegsheim, Noor Gammoh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Autophagy is a finely orchestrated process required for the lysosomal degradation of cytosolic components. The final degradation step is essential for clearing autophagic cargo and recycling macromolecules. Using a CRISPR/Cas9-based screen,
Externí odkaz:
https://doaj.org/article/6883251db50c4cf790616ebe8bd9529f
Publikováno v:
Chemometrics and Cheminformatics in Aquatic Toxicology. :243-274
Autor:
Alina Bora, Simona Funar‐Timofei
Publikováno v:
Chemometrics and Cheminformatics in Aquatic Toxicology. :377-389
Physicians have the freedom to prescribe medicines outside the list of approved indications, to treat mild to life-threatening clinical conditions and diseases, particularly when conventional treatments fail or are lacking. Off-label drug usage is mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20dab0a088baa9c961c8cf88774fa335
https://doi.org/10.1101/2022.09.08.22279709
https://doi.org/10.1101/2022.09.08.22279709
Autor:
Sorin Avram, Mircea Mracec, Alina Bora, Liliana Halip, Ana Borota, Ramona Curpan, Maria Mracec
Publikováno v:
Structural Chemistry. 32:1141-1149
In the context of unknowing the experimental structure for histamine H3 receptor, which is a potential therapeutical target for numerous disorders and diseases, the theoretical methods can bring light and necessary information for a better understand