Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Alina, Borchers"'
Autor:
Lisa-Marie Rieckmann, Michael Spohn, Lisa Ruff, David Agorku, Lisa Becker, Alina Borchers, Jenny Krause, Roisin O’Reilly, Jurek Hille, Janna-Lisa Velthaus-Rusik, Niklas Beumer, Armin Günther, Lena Willnow, Charles D. Imbusch, Peter Iglauer, Ronald Simon, Sören Franzenburg, Hauke Winter, Michael Thomas, Carsten Bokemeyer, Nicola Gagliani, Christian F. Krebs, Martin Sprick, Olaf Hardt, Sabine Riethdorf, Andreas Trumpp, Nikolas H. Stoecklein, Sven Peine, Philipp Rosenstiel, Klaus Pantel, Sonja Loges, Melanie Janning
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-9 (2024)
Abstract Background Circulating tumor cells (CTCs) hold immense promise for unraveling tumor heterogeneity and understanding treatment resistance. However, conventional methods, especially in cancers like non-small cell lung cancer (NSCLC), often yie
Externí odkaz:
https://doaj.org/article/2c341ef7571b4502937a3beb26a74b4b
Autor:
Jan-Hendrik Riedel, Lennart Robben, Hans-Joachim Paust, Yu Zhao, Nariaki Asada, Ning Song, Anett Peters, Anna Kaffke, Alina Borchers, Gisa Tiegs, Larissa Seifert, Nicola M. Tomas, Elion Hoxha, Ulrich O. Wenzel, Tobias B. Huber, Thorsten Wiech, Jan-Eric Turner, Christian F. Krebs, Ulf Panzer
Publikováno v:
JCI Insight, Vol 8, Iss 1 (2023)
Glucocorticoids remain a cornerstone of therapeutic regimes for autoimmune and chronic inflammatory diseases — for example, in different forms of crescentic glomerulonephritis — because of their rapid antiinflammatory effects, low cost, and wide
Externí odkaz:
https://doaj.org/article/6443c52a90ff43ecadb3bda903f06ac0
Autor:
Patricia Bartsch, Christoph Kilian, Malte Hellmig, Hans-Joachim Paust, Alina Borchers, Amirrtavarshni Sivayoganathan, Leon Enk, Yu Zhao, Nikhat Shaikh, Henning Büttner, Milagros N Wong, Victor G Puelles, Thorsten Wiech, Richard Flavell, Tobias B Huber, Jan-Eric Turner, Stefan Bonn, Samuel Huber, Nicola Gagliani, Hans-Willi Mittrücker, Holger Rohde, Ulf Panzer, Christian F Krebs
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1010430 (2022)
Staphylococcus aureus is frequently detected in patients with sepsis and thus represents a major health burden worldwide. CD4+ T helper cells are involved in the immune response to S. aureus by supporting antibody production and phagocytosis. In part
Externí odkaz:
https://doaj.org/article/380fd4269d2449729d87e44af873b2c2
Autor:
Likai Tan, Inga Sandrock, Ivan Odak, Yuval Aizenbud, Anneke Wilharm, Joana Barros-Martins, Yaara Tabib, Alina Borchers, Tiago Amado, Lahiru Gangoda, Marco J. Herold, Marc Schmidt-Supprian, Jan Kisielow, Bruno Silva-Santos, Christian Koenecke, Avi-Hai Hovav, Christian Krebs, Immo Prinz, Sarina Ravens
Publikováno v:
Cell Reports, Vol 27, Iss 12, Pp 3657-3671.e4 (2019)
Summary: IL-17-producing γδ T cells express oligoclonal Vγ4+ and Vγ6+ TCRs, mainly develop in the prenatal thymus, and later persist as long-lived self-renewing cells in all kinds of tissues. However, their exchange between tissues and the mechan
Externí odkaz:
https://doaj.org/article/ec7de8c74d424a13bcfd9f15aebb183d
Autor:
Hans-Joachim Paust, Ning Song, Donatella De Feo, Nariaki Asada, Selma Tuzlak, Yu Zhao, Jan-Hendrik Riedel, Malte Hellmig, Amirrtavarshni Sivayoganathan, Anett Peters, Anna Kaffke, Alina Borchers, Ulrich O. Wenzel, Oliver M. Steinmetz, Gisa Tiegs, Elisabeth Meister, Matthias Mack, Christian Kurts, Sibylle von Vietinghoff, Maja T. Lindenmeyer, Elion Hoxha, Rolf A. K. Stahl, Tobias B. Huber, Stefan Bonn, Catherine Meyer-Schwesinger, Thorsten Wiech, Jan-Eric Turner, Burkhard Becher, Christian F. Krebs, Ulf Panzer
Publikováno v:
Science Translational Medicine. 15
GM-CSF in glomerulonephritis Despite glomerulonephritis being an immune-mediated disease, the contributions of individual immune cell types are not clear. To address this gap in knowledge, Paust et al . characterized pathological immune cells in samp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51ff737a171d8c56e5892182887e80eb
https://doi.org/10.1126/scitranslmed.add6137
https://doi.org/10.1126/scitranslmed.add6137
Autor:
Shiwa Soukou-Wargalla, Christoph Kilian, Lis Velasquez, Andres Machicote, Franziska Bertram, Friederike Stumme, Tanja Bedke, Anastasios Giannou, Jan Kempski, Morsal Sabihi, Ning Song, Hans-Joachim Paust, Alina Borchers, Laura Garcia Perez, Penelope Pelczar, Beibei Liu, Can Ergen, Babett Steglich, Franziska Muscate, Tobias B. Huber, Ulf Panzer, Nicola Gagliani, Christian F. Krebs, Samuel Huber
SummaryT regulatory type 1 (Tr1) cells, which are defined by their regulatory function, lack of Foxp3, high expression of IL-10, CD49b, and LAG3, are known to be able to suppress Th1 and Th17 in the intestine. Th1 and Th17 cells are also the main dri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74640282a334d66b783c287232c37ac3
https://doi.org/10.1101/2023.02.07.527417
https://doi.org/10.1101/2023.02.07.527417
Autor:
Jan-Hendrik Riedel, Alina Borchers, Nariaki Asada, Anett Peters, Tilman Schmidt, Ulf Panzer, Pauline Ginsberg, Hans-Joachim Paust, Samuel Huber, Tobias B. Huber, Christian Krebs, Nicola Gagliani, Ning Song, Richard A. Flavell, Anna Kaffke, Jonas Luebbe, Jan-Eric Turner, Lennart Robben, Penelope Pelzcar, Sonja Hiekmann, Christoph Kilian
Publikováno v:
J Am Soc Nephrol
BACKGROUND: IL-17A–producing CD4(+) T helper (T(H)17) cells play a critical role in autoimmune and chronic inflammatory diseases, such as crescentic GN. The proinflammatory effects of IL-17 are mediated by the activation of the IL-17RA/IL-17RC comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b559a2cd1ee4dd27d7cad7fa2b815888
https://doi.org/10.1681/asn.2021030426
https://doi.org/10.1681/asn.2021030426
Autor:
Jan-Hendrik Riedel, Lennart Robben, Hans-Joachim Paust, Yu Zhao, Nariaki Asada, Ning Song, Anett Peters, Anna Kaffke, Alina Borchers, Gisa Tiegs, Larissa Seifert, Nicola M. Tomas, Elion Hoxha, Ulrich O. Wenzel, Tobias B. Huber, Thorsten Wiech, Jan-Eric Turner, Christian F. Krebs, Ulf Panzer
Publikováno v:
JCI insight.
Glucocorticoids remain a cornerstone of therapeutic regimes for autoimmune and chronic inflammatory diseases, for example, in different forms of crescentic glomerulonephritis because of their rapid anti-inflammatory effects, low cost, and wide availa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d75733e60b64fb7d63aca69e0484b2
https://pubmed.ncbi.nlm.nih.gov/36355429
https://pubmed.ncbi.nlm.nih.gov/36355429
Autor:
Reinhold Förster, Bowen Zhang, Alina Borchers, Ulf Panzer, Constantin von Kaisenberg, Christian Koenecke, Christian Schultze-Florey, Immo Prinz, Anja Bubke, Elena Bruni, Yang Li, Alina Suzann Fichtner, Xiaojing Chu, Inga Sandrock, Likai Tan, Ansgar Schulz, Sarina Ravens, Ivan Odak, Michael Jarek, Christian Krebs
Publikováno v:
Science immunology, 6(58):0125. AMER ASSOC ADVANCEMENT SCIENCE
Accumulating evidence suggests that the mouse embryonic thymus produces distinct waves of innate effector gamma delta T cells. However, it is unclear whether this process occurs similarly in humans and whether it comprises a dedicated subset of innat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e31f77f73d2bafbe73157f8c2b6040
https://research.rug.nl/en/publications/6008b9bb-7fc4-411e-ae2d-527bbbe36eb0
https://research.rug.nl/en/publications/6008b9bb-7fc4-411e-ae2d-527bbbe36eb0
Autor:
Francesco Siracusa, Ansgar W. Lohse, Dominik Kylies, Filippo Cortesi, Yu Zhao, Mascha Binder, Nicola Gagliani, Susanne Pfefferle, Milagros N. Wong, Victor G. Puelles, Marissa Herrmann, Lidia Bosurgi, Christoph Schultheiß, Leon U. B. Enk, Patricia Bartsch, Stefan Bonn, Malte Hellmig, Ulf Panzer, Kevin Roedl, Dominik Jarczak, Elisa Rosati, Samuel Huber, Petra Bacher, Jan-Eric Turner, Christoph Kilian, Christian Krebs, Jan-Peter Sperhake, Ann-Christin Gnirck, Marc Lütgehetmann, Julian Schulze Zur-Wiesch, Stefan Steurer, Alina Borchers, Nicola Scheibel, Stefan Kluge, Marylyn M. Addo, Hans-Joachim Paust, Tobias B. Huber, Fabian Hausmann
Publikováno v:
Science Immunology. 6
Hyperinflammation contributes to lung injury and subsequent acute respiratory distress syndrome (ARDS) with high mortality in patients with severe coronavirus disease 2019 (COVID-19). To understand the underlying mechanisms involved in lung pathology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4a5ccddc6a55c72f86683a58fce8cc
https://doi.org/10.1126/sciimmunol.abf6692
https://doi.org/10.1126/sciimmunol.abf6692