Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Aliki Perdikari"'
Autor:
Vissarion Efthymiou, Lianggong Ding, Miroslav Balaz, Wenfei Sun, Lucia Balazova, Leon G. Straub, Hua Dong, Eric Simon, Adhideb Ghosh, Aliki Perdikari, Svenja Keller, Umesh Ghoshdastider, Carla Horvath, Caroline Moser, Bradford Hamilton, Heike Neubauer, Christian Wolfrum
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract The current obesity epidemic and high prevalence of metabolic diseases necessitate efficacious and safe treatments. Brown adipose tissue in this context is a promising target with the potential to increase energy expenditure, however no phar
Externí odkaz:
https://doaj.org/article/ef281b42140141c1891ca96fd175d996
Autor:
Aliki Perdikari, Tessa Cacciottolo, Elana Henning, Edson Mendes de Oliveira, Julia M. Keogh, I. Sadaf Farooqi
Publikováno v:
Open Biology, Vol 12, Iss 3 (2022)
Obesity, defined as an excess of adipose tissue that adversely affects health, is a major cause of morbidity and mortality. However, to date, understanding the structure and function of human adipose tissue has been limited by the inability to visual
Externí odkaz:
https://doaj.org/article/bbcbc4efd32342f28040931f56db7f20
Autor:
Sebastian Müller, Aliki Perdikari, Dianne H. Dapito, Wenfei Sun, Bernd Wollscheid, Miroslav Balaz, Christian Wolfrum
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
When exposed to cold temperatures, mice increase their thermogenic capacity by an expansion of brown adipose tissue mass and the formation of brite/beige adipocytes in white adipose tissue depots. However, the process of the transcriptional changes u
Externí odkaz:
https://doaj.org/article/cfd0814f89bd4eb79c30e21ead6f2e52
Autor:
Aliki Perdikari, Germán Gastón Leparc, Miroslav Balaz, Nuno D. Pires, Martin E. Lidell, Wenfei Sun, Francesc Fernandez-Albert, Sebastian Müller, Nassila Akchiche, Hua Dong, Lucia Balazova, Lennart Opitz, Eva Röder, Holger Klein, Patrik Stefanicka, Lukas Varga, Pirjo Nuutila, Kirsi A. Virtanen, Tarja Niemi, Markku Taittonen, Gottfried Rudofsky, Jozef Ukropec, Sven Enerbäck, Elia Stupka, Heike Neubauer, Christian Wolfrum
Publikováno v:
Cell Reports, Vol 25, Iss 3, Pp 784-797.e4 (2018)
Summary: Recruitment and activation of thermogenic adipocytes have received increasing attention as a strategy to improve systemic metabolic control. The analysis of brown and brite adipocytes is complicated by the complexity of adipose tissue biopsi
Externí odkaz:
https://doaj.org/article/e91244b87ff84ba1bb8eb4ec6ba835f6
Autor:
Sadaf Farooqi, Aliki Perdikari
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81442110868c2030139a39c08c3e4287
https://doi.org/10.1016/b978-0-12-821618-7.00281-9
https://doi.org/10.1016/b978-0-12-821618-7.00281-9
Autor:
Yang He, Bas Brouwers, Hesong Liu, Hailan Liu, Katherine Lawler, Edson Mendes de Oliveira, Dong-Kee Lee, Yongjie Yang, Aaron R. Cox, Julia M. Keogh, Elana Henning, Rebecca Bounds, Aliki Perdikari, Vikram Ayinampudi, Chunmei Wang, Meng Yu, Longlong Tu, Nan Zhang, Na Yin, Junying Han, Nikolas A. Scarcelli, Zili Yan, Kristine M. Conde, Camille Potts, Jonathan C. Bean, Mengjie Wang, Sean M. Hartig, Lan Liao, Jianming Xu, Inês Barroso, Jacek Mokrosinski, Yong Xu, I. Sadaf Farooqi
Funder: National Institute for Health Research (NIHR)
Serotonin reuptake inhibitors and receptor agonists are used to treat obesity, anxiety and depression. Here we studied the role of the serotonin 2C receptor (5-HT2CR) in weight regulation and
Serotonin reuptake inhibitors and receptor agonists are used to treat obesity, anxiety and depression. Here we studied the role of the serotonin 2C receptor (5-HT2CR) in weight regulation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e7fcce37e71b8dfb698909029b7e74
https://www.repository.cam.ac.uk/handle/1810/344906
https://www.repository.cam.ac.uk/handle/1810/344906
Autor:
Aliki Perdikari, Jacek Mokrosinski, Tabitha Randell, I. Sadaf Farooqi, Sharon Lim, Fleur Talbot, Rebecca Bounds, Melanie Kershaw, Deepthi Jyothish, Edson Mendes de Oliveira, Tim Cheetham, Antoinette McAulay, Vikram Ayinampudi, Elizabeth C Crowne, Inês Barroso, Peter T Clayton, Praveen Partha, Cristina Matei, Sanjay Gupta, Louise C Wilson, Elana Henning, Keogh Jm, Rachel Ahmed, Natalia Wasiluk
Publikováno v:
New England Journal of Medicine. 385:1581-1592
Background GNAS encodes the Gαs (stimulatory G-protein alpha subunit) protein, which mediates G protein-coupled receptor (GPCR) signaling. GNAS mutations cause developmental delay, short stature, and skeletal abnormalities in a syndrome called Albri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::255b2c7cc5235878185fe46e905905d4
https://doi.org/10.1056/nejmoa2103329
https://doi.org/10.1056/nejmoa2103329
Autor:
I. Sadaf Farooqi, Aliki Perdikari, Julia M. Keogh, Elana Henning, Tessa M. Cacciottolo, Edson Mendes de Oliveira
Publikováno v:
Open Biology. 12
Peer reviewed: True
Funder: Bernard Wolfe Health Neuroscience Endowment
Funder: Botnar Fondation
Funder: NIHR Cambridge Biomedical Research Center
Funder: NIHR Senior Investigator Award
Obesity, defined as an excess of adipos
Funder: Bernard Wolfe Health Neuroscience Endowment
Funder: Botnar Fondation
Funder: NIHR Cambridge Biomedical Research Center
Funder: NIHR Senior Investigator Award
Obesity, defined as an excess of adipos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d2c33adbc07fe79af4c1965170a54c
https://doi.org/10.1098/rsob.210345
https://doi.org/10.1098/rsob.210345
Autor:
Tessa M Cacciottolo, Elana Henning, Julia M Keogh, Pierre Bel Lassen, Katherine Lawler, Rebecca Bounds, Rachel Ahmed, Aliki Perdikari, Edson Mendes de Oliveira, Miriam Smith, Edmund M Godfrey, Elspeth Johnson, Leanne Hodson, Karine Clément, Agatha A van der Klaauw, I Sadaf Farooqi
Publikováno v:
Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, 2022, ⟨10.1210/clinem/dgac067/6524195⟩
Journal of Clinical Endocrinology and Metabolism, 2022, ⟨10.1210/clinem/dgac067/6524195⟩
Context Genetic variants affecting the nuclear hormone receptor coactivator steroid receptor coactivator, SRC-1, have been identified in people with severe obesity and impair melanocortin signaling in cells and mice. As a result, obese patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4969263f22143723eca8e4abfd413c4
https://hal.sorbonne-universite.fr/hal-03565637/file/dgac067.pdf
https://hal.sorbonne-universite.fr/hal-03565637/file/dgac067.pdf
Autor:
null Aliki Perdikari, null Tessa Cacciottolo, null Elana Henning, null Edson Mendes de Oliveira, null Julia M. Keogh, null I. Sadaf Farooqi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4caf77d547f8080d9435759895b3be9
https://doi.org/10.1098/rsob.210345/v2/response1
https://doi.org/10.1098/rsob.210345/v2/response1