Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alies A. van Mullem"'
Autor:
Anja L M van Gucht, W. Edward Visser, Theo J. Visser, Robin P. Peeters, Alies A.A. van Mullem, Marcel E Meima
Publikováno v:
Molecular and Cellular Endocrinology, 437(C), 252-260. Elsevier Ireland Ltd
Transport of thyroid hormone (TH) across the plasma membrane is necessary for the genomic action of T3 mediated by its nuclear T3 receptor. MCT8 and MCT10 have been identified as important TH transporters. Mutations in MCT8 result in severe psychomot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::725b5f134179bfe34f12c169481a991e
https://hdl.handle.net/1765/97359
https://hdl.handle.net/1765/97359
Autor:
Joanne M. Donkers, Alies A.A. van Mullem, Anja L M van Gucht, Giulia Brigante, Theo J. Visser, Simone Kersseboom, Stan F.J. van de Graaf, Bo Carlsson, Stefania Farina, Robin P. Peeters
Publikováno v:
Endocrinology, 158(10), 3307-3318. The Endocrine Society
Endocrinology, 158(10), 3307-3318. Endocrine Society
Endocrinology, 158(10), 3307-3318. Endocrine Society
The thyroid hormone (TH) analog eprotirome (KB2115) was developed to lower cholesterol through selective activation of the TH receptor (TR) β1 in the liver. Interestingly, eprotirome shows low uptake in nonhepatic tissues, explaining its lipid-lower
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b972e0648dc84893c2c4e59e3be9ddc
https://pure.amc.nl/en/publications/role-of-the-bile-acid-transporter-slc10a1-in-liver-targeting-of-the-lipidlowering-thyroid-hormone-analog-eprotirome(661bf35f-8148-487e-970f-00eb1d3c0cff).html
https://pure.amc.nl/en/publications/role-of-the-bile-acid-transporter-slc10a1-in-liver-targeting-of-the-lipidlowering-thyroid-hormone-analog-eprotirome(661bf35f-8148-487e-970f-00eb1d3c0cff).html
Autor:
Veerle Darras, Andreas J. R. Habenicht, Alies A. van Mullem, Theo J. Visser, Claudia Groba, H Heuer, Steffen Mayerl
Publikováno v:
Molecular Endocrinology, 27(4), 586-597. The Endocrine Society
The impact of thyroid hormone (TH) on metabolism and energy expenditure is well established, but the role of TH in regulating nutritional sensing, particularly in the central nervous system, is only poorly defined. Here, we studied the consequences o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f28e86b2f69954bcdd5c90ea5129b6
https://doi.org/10.1210/me.2012-1311
https://doi.org/10.1210/me.2012-1311
Publikováno v:
Molecular and Cellular Endocrinology, 337(1-2), 96-100. Elsevier Ireland Ltd
Thyroid hormone (TH) transporter proteins mediate transport of TH across the plasma membrane, thereby facilitating its intracellular bioavailability. As only a few transporters have been identified which are relatively specific for TH, including mono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb549f9709ed9a5f475d9d3d2e23bfb
https://doi.org/10.1016/j.mce.2011.02.003
https://doi.org/10.1016/j.mce.2011.02.003
Thyroid hormone (TH) exerts its biological activity via the TH receptors TRα1 and TRβ1/2, which are encoded by the THRA and THRB genes. The first patients with mutations in THRB were identified decades ago. These patients had a clinical syndrome of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e37a7ce18e6eb7360091ef966768fde
https://europepmc.org/articles/PMC4005264/
https://europepmc.org/articles/PMC4005264/
Publikováno v:
Clinical Endocrinology, 79(5), 595-605. Wiley-Blackwell Publishing Ltd
Normal thyroid hormone (TH) metabolism and action require adequate cellular TH signalling. This entails proper function of TH transporters in the plasma membrane, intracellular deiodination of TH and action of the bioactive hormone T3 at its nuclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf39cceb6ac65c484cc4d7d3c492357
https://pubmed.ncbi.nlm.nih.gov/23834164
https://pubmed.ncbi.nlm.nih.gov/23834164
Autor:
E. Chroni, Alexandra Eythimiadou, W. Edward Visser, Agathocles Tsatsoulis, Alies A.A. van Mullem, Theo J. Visser, Dionisios Chrysis, Robin P. Peeters, Yolanda B. de Rijke
Publikováno v:
Journal of Clinical Endocrinology and Metabolism, 98(7), 3029-3038. Endocrine Society
Context: Recently the first patients with inactivating mutations in T-3 receptor (TR)-alpha 1 have been identified. These patients have low free T-4, low T-4, high T-3, low rT(3), and normal TSH serum levels, in combination with growth retardation, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ddf5414c565d7d57d1903411943902
https://pubmed.ncbi.nlm.nih.gov/23837191
https://pubmed.ncbi.nlm.nih.gov/23837191
Autor:
Joachim Geyer, Alies A.A. van Mullem, Theo J. Visser, W. Edward Visser, Edith C. H. Friesema, Wing S. Wong
Publikováno v:
Molecular and Cellular Endocrinology
Molecular and Cellular Endocrinology, Elsevier, 2009, 315 (1-2), pp.138. ⟨10.1016/j.mce.2009.08.003⟩
Molecular and Cellular Endocrinology, 315(1-2), 138-145. Elsevier Ireland Ltd
Molecular and Cellular Endocrinology, Elsevier, 2009, 315 (1-2), pp.138. ⟨10.1016/j.mce.2009.08.003⟩
Molecular and Cellular Endocrinology, 315(1-2), 138-145. Elsevier Ireland Ltd
Transport of (sulfated) iodothyronines across the plasma membrane is required for their intracellular metabolism. Rat Na+/taurocholate cotransporting polypeptide (Ntcp: Slc10al) has been identified as an important transporter protein. We demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6854be6693a16c6506c04499e5d0208f
https://hal.archives-ouvertes.fr/hal-00547654
https://hal.archives-ouvertes.fr/hal-00547654
Autor:
Anton P. van Zanten, Roy E. Weiss, Jan Kvetny, Samuel Refetoff, Mahdi Kamoun, Tina Toft Kristensen, Krishna Chatterjee, Anne-Dorthe Feldthusen, Teresa S. Kasamatsu, Rosalia P. Padovani, Juan Bernal, Athanasios Panagiotou, Theo J. Visser, Palle Pedersen, Leslie J. De Groot, Pieter H. Reitsma, F. Anders Karlsson, Patrick Sheahan, Christina Ellervik, J.M.L. Tsitsi, Druckerei Stückle, Peter Kopp, Jan Debeij, Rania Mehanna, Armelle Fayard, J. H. Duncan Bassett, Alexandra M. Dumitrescu, Graham R. Williams, Amira Y. Albusta, Hanno Pijl, Jacob Larsen, Elza S. Ikejiri, Albana Sykja, Yoshiharu Murata, Gregory A. Brent, Cleber P. Camacho, Felipe Crispim, Olaf M. Dekkers, Bregje van Zaane, Rachel Desailloud, C. Mari Aparici, Esther J van Zuuren, R. Shires, Paul M. Yen, Marina Kita, Ben Carter, Rui M. B. Maciel, Peter Lindgren, G. Teckie, Søren Jelstrup, Michèle d'Herbomez, Christine Lemaire, Luca Persani, Selwan Khamisi, Jairo Tabacow Hidal, Claudia A. Yamazaki, José Gilberto H. Vieira, Wilmar M. Wiersinga, J. Larry Jameson, Jean-Louis Wémeau, John Lazarus, Victor E. A. Gerdes, Rosa Paula M. Biscolla, Zbys Fedorowicz, Robin P. Peeters, Suzanne C. Cannegieter, Matthew S. Murphy, Jairo Wagner, Zoe Efstathiadou, Jacques Samarut, Cláudia C. D. Nakabashi, S.A. Bhana, Maria C.O.M. Mamone, Alies A. van Mullem, T. Liu, Damien Huglo, Frits R. Rosendaal, Flávia C. Aldighieri, Danielle M. Andreoni, Paolo Beck-Peccoz, Panagiotis Anagnostis
Publikováno v:
European Thyroid Journal. 1:X-X
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07742e073f6567d536a3b71e241c3c1a
https://doi.org/10.1159/000341866
https://doi.org/10.1159/000341866
Autor:
Kersseboom S; Department of Internal Medicine and Rotterdam Thyroid Center, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands., van Gucht ALM; Department of Internal Medicine and Rotterdam Thyroid Center, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands., van Mullem A; Department of Internal Medicine and Rotterdam Thyroid Center, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands., Brigante G; Department of Internal Medicine and Rotterdam Thyroid Center, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands., Farina S; Department of Internal Medicine and Rotterdam Thyroid Center, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands., Carlsson B; Karo Bio AB, Novum Research Park, Huddinge S-141 57, Sweden., Donkers JM; Tytgat Institute for Liver and Intestinal Research and Department of Gastroenterology and Hepatology, Amsterdam Medical Center, 1105 AZ Amsterdam, The Netherlands., van de Graaf SFJ; Tytgat Institute for Liver and Intestinal Research and Department of Gastroenterology and Hepatology, Amsterdam Medical Center, 1105 AZ Amsterdam, The Netherlands., Peeters RP; Department of Internal Medicine and Rotterdam Thyroid Center, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands., Visser TJ; Department of Internal Medicine and Rotterdam Thyroid Center, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands.
Publikováno v:
Endocrinology [Endocrinology] 2017 Oct 01; Vol. 158 (10), pp. 3307-3318.