Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Alie Wudwud"'
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The impact of double sequential external defibrillation on termination of refractory ventricular fibrillation during out-of-hospital cardiac arrest
Autor: Jim Summers, Sheldon Cheskes, P. Richard Verbeek, Laurie J. Morrison, Alie Wudwud, Shelley McLeod, Linda Turner
Publikováno v: Resuscitation. 139
Background Despite significant advances in resuscitation efforts, there are some patients who remain in ventricular fibrillation (VF) after multiple shocks during out-of-hospital cardiac arrest (OHCA). Double sequential external defibrillation (DSED)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76f7c58d136fd1d2d9e4909f02898d76
https://pubmed.ncbi.nlm.nih.gov/31059670
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3
Adaptive phenotypic modulation of human arterial endothelial cells to fluid shear stress-encoded signals: modulation by phosphodiesterase 4D-VE-cadherin signalling
Autor: Sarah N. Rampersad, Donald H. Maurice, Fabien Hubert, Alie Wudwud
Publikováno v: Cellular Signalling. 28:741-748
Although cAMP-signalling regulates numerous functions of vascular endothelial cells (VECs), including their ability to impact vascular resistance in response to changes in blood flow dynamics, few of the mechanisms underlying these effects have yet t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e58013e38ee30eb8736772cf80615e9
https://doi.org/10.1016/j.cellsig.2015.12.001
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4
EPAC1 promotes adaptive responses in human arterial endothelial cells subjected to low levels of laminar fluid shear stress: Implications in flow-related endothelial dysfunction
Autor: Sarah N. Rampersad, Paulina Brzezinska, M. Bibiana Umana, Donald H. Maurice, Fabien Hubert, Alie Wudwud, Nathalie Butler, Silja I. Freitag
Publikováno v: Cellular signalling. 28(6)
Blood flow-associated fluid shear stress (FSS) dynamically regulates the endothelium's ability to control arterial structure and function. While arterial endothelial cells (AEC) subjected to high levels of laminar FSS express a phenotype resistant to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4623e212f1b85c22ff0d29fb8247a9
https://pubmed.ncbi.nlm.nih.gov/26979996
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5
cAMP‐signaling via EPAC1 mediates vascular endothelial cell adaptation to fluid‐shear stress
Autor: Fabien Hubert, Donald H. Maurice, M Umana, Silja I. Freitag, Nathalie Butler, Paulina Brzezinska, Alie Wudwud, Sarah N. Rampersad
Publikováno v: The FASEB Journal. 29
Herein, we report a novel role for cAMP-signaling in human aortic endothelial cell (HAEC) adaptation to fluid-mediated shear stress (FSS). Our results showed that increases in cAMP enhanced elongat...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f9bbdd2d829158e14a7a5e41868c6c38
https://doi.org/10.1096/fasebj.29.1_supplement.625.2
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6
Target of selective cyclic nucleotide phosphodiesterases differentially regulates arterial myocyte migration (1065.3)
Autor: Paulina Brzezinska, M Umana, Fabien Hubert, Alie Wudwud, Donald H. Maurice, Sarah N. Rampersad, Silja I. Freitag
Publikováno v: The FASEB Journal. 28
Vascular myocyte (VSMC) migration is a vital process allowing for the regulation of vascular development, tissue repair and the modulation of pathophysiological conditions including atherosclerosis. Atherosclerosis induced damage to the vascular endo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9b292e74bfebacd222b0b11342bf1e17
https://doi.org/10.1096/fasebj.28.1_supplement.1065.3
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8
Cyclic nucleotide phosphodiesterases (PDEs): coincidence detectors acting to spatially and temporally integrate cyclic nucleotide and non-cyclic nucleotide signals
Autor: Paulina Brzezinska, Sarah N. Rampersad, Fabien Hubert, Donald H. Maurice, Lindsay S. Wilson, M. Bibiana Umana, Milosz Kaczmarek, Tammy K. Truong, Alie Wudwud, Silja I. Freitag
Publikováno v: Biochemical Society transactions. 42(2)
The cyclic nucleotide second messengers cAMP and cGMP each affect virtually all cellular processes. Although these hydrophilic small molecules readily diffuse throughout cells, it is remarkable that their ability to activate their multiple intracellu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454c229a3e099b3e00d31f25981f75b1
https://pubmed.ncbi.nlm.nih.gov/24646226
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