Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Alicja Zylicz"'
Autor:
Sara Donzelli, Elisa Milano, Magdalena Pruszko, Andrea Sacconi, Silvia Masciarelli, Ilaria Iosue, Elisa Melucci, Enzo Gallo, Irene Terrenato, Marcella Mottolese, Maciej Zylicz, Alicja Zylicz, Francesco Fazi, Giovanni Blandino, Giulia Fontemaggi
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-15 (2018)
Abstract Background As crucial regulators of the immune response against pathogens, macrophages have been extensively shown also to be important players in several diseases, including cancer. Specifically, breast cancer macrophages tightly control th
Externí odkaz:
https://doaj.org/article/a7369b493aa94dc2b68ffa9d49bbb496
Autor:
Milena Wiech, Maciej B. Olszewski, Zuzanna Tracz-Gaszewska, Bartosz Wawrzynow, Maciej Zylicz, Alicja Zylicz
Publikováno v:
PLoS ONE, Vol 8, Iss 8 (2013)
Externí odkaz:
https://doaj.org/article/6f538a4cb6ff4c71ab9fe1837caff967
Autor:
Milena Wiech, Maciej B Olszewski, Zuzanna Tracz-Gaszewska, Bartosz Wawrzynow, Maciej Zylicz, Alicja Zylicz
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51426 (2012)
Numerous p53 missense mutations possess gain-of-function activities. Studies in mouse models have demonstrated that the stabilization of p53 R172H (R175H in human) mutant protein, by currently unknown factors, is a prerequisite for its oncogenic gain
Externí odkaz:
https://doaj.org/article/3c0d7f067b7448d8a5adb06ecb1fc2ce
Autor:
Bartosz Wawrzynow, Marcin Herok, Marta J Maluszek, Maciej B. Olszewski, Maciej Zylicz, Alicja Zylicz
Publikováno v:
Cancers
Volume 13
Issue 18
Cancers, Vol 13, Iss 4501, p 4501 (2021)
Volume 13
Issue 18
Cancers, Vol 13, Iss 4501, p 4501 (2021)
Simple Summary MDM2 is a protein responsible for negative regulation of the p53 tumor suppressor. In addition, MDM2 exhibits chaperone-like properties similar to the HSP90 molecular chaperone. Multiple studies revealed that MDM2 is deeply involved in
Autor:
Nadinath B. Nillegoda, Ryo Ushioda, Richard Zimmermann, Chandan Sahi, Jason C. Young, Douglas M. Cyr, Carlos H.I. Ramos, Kazuhiro Nagata, Rina Rosenzweig, Elizabeth A. Craig, Krzysztof Liberek, Alicja Zylicz, Janine Kirstein, Michael E. Cheetham, Harm H. Kampinga, Pablo Pulido, Jason E. Gestwicki, Mikko Taipale, Bratłomiej Tomiczek, Claes Andréasson, Alessandro Barducci, Cecilia Emanuelsson, Sabine Rospert, Jaroslaw Marszalek, Pierre Genevaux, Paolo De Los Rios, Matthias P. Mayer, Jaime Huerta-Cepas, Pierre Goloubinoff, Maciej Zylicz
Publikováno v:
Cell stress & chaperones, vol 24, iss 1
Hsp70 chaperone systems are very versatile machines present in nearly all living organisms and in nearly all intracellular compartments. They function in many fundamental processes through their facilitation of protein (re)folding, trafficking, remod
Autor:
Damian Robert Sojka, Agnieszka Gogler-Pigłowska, Alicja Zylicz, Magdalena Głowala-Kosińska, Katarzyna Klarzyńska, Zdzisław Krawczyk, Marta Klimczak, Dorota Scieglinska
Publikováno v:
Cancers
Volume 12
Issue 10
Cancers, Vol 12, Iss 2749, p 2749 (2020)
Volume 12
Issue 10
Cancers, Vol 12, Iss 2749, p 2749 (2020)
Heat Shock Protein A2 (HSPA2) is a member of the HSPA (HSP70) chaperone family and has a critical role for male fertility. HSPA2 is present in a number of somatic organs. Limited evidence suggests that HSPA2 may be involved in regulating epithelial c
Autor:
Lukasz Zyla, Magdalena Pruszko, Michalina Wezyk, Dawid Walerych, Alicja Zylicz, Katarzyna Gaweda-Walerych
Publikováno v:
Oncotarget
// Dawid Walerych 1 , Magdalena Pruszko 1 , Lukasz Zyla 2 , Michalina Wezyk 1 , Katarzyna Gaweda-Walerych 1 and Alicja Zylicz 2 1 Mossakowski Medical Research Centre, Polish Academy of Sciences, 02-106 Warsaw, Poland 2 International Institute of Mole
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1869:161-174
Organized networks of heat shock proteins, which possess molecular chaperone activity, protect cells from abrupt environmental changes. Additionally, molecular chaperones are essential during stress-free periods, where they moderate housekeeping func
Autor:
Zuzanna Tracz-Gaszewska, Marcin Herok, Marcin Kosinski, Marta Klimczak, Przemyslaw Biecek, Bartosz Wawrzynow, Milena Wiech, Patrycja Czerwińska, Maciej Wiznerowicz, Alicja Zylicz, Maciej B. Olszewski, Maciej Zylicz
Publikováno v:
Oncotarget. 8:82123-82143
Utilizing the TCGA PANCAN12 dataset we discovered that cancer patients with mutations in TP53 tumor suppressor and overexpression of MDM2 oncogene exhibited decreased survival post treatment. Interestingly, in the case of breast cancer patients, this
Autor:
Magdalena Pruszko, Giovanni Blandino, Maciej Zylicz, Elisa Milano, Giulia Fontemaggi, Alicja Zylicz
Publikováno v:
Journal of Thoracic Disease. 10:E231-E233
We appreciate the interest and the editorial comments of Luo J and Fan S on our article “The mutant p53-ID4 complex controls VEGFA isoforms by recruiting lncRNA MALAT1”, recently published in EMBO Reports (1). We agree with the first criticism ra