Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Alicja Winczura"'
Autor:
Katarzyna Urbanek-Olejnik, Monika Liszewska, Alicja Winczura, Agnieszka Hernik, Paweł Struciński, Jan K. Ludwicki
Publikováno v:
Roczniki Panstwowego Zakladu Higieny, Vol 69, Iss 3, Pp 307-314 (2018)
Background. The changes in DNA methylation are considered as one of the early events in hepatocarcinogenesis. Objective. We evaluated the ability of phenobarbital (PB) – the most widely used anticonvulsant worldwide and classical rodent liver carc
Externí odkaz:
https://doaj.org/article/febf055b18434e999ca1661f976b6c94
Publikováno v:
PLoS Genetics, Vol 15, Iss 11, p e1008427 (2019)
Replication fork stalling and accumulation of single-stranded DNA trigger the S phase checkpoint, a signalling cascade that, in budding yeast, leads to the activation of the Rad53 kinase. Rad53 is essential in maintaining cell viability, but its targ
Externí odkaz:
https://doaj.org/article/48d5d5c5cb67477b9ee3b05d50d622d3
Autor:
Tomasz Dziaman, Hubert Ludwiczak, Jaroslaw M Ciesla, Zbigniew Banaszkiewicz, Alicja Winczura, Mateusz Chmielarczyk, Ewa Wisniewska, Andrzej Marszalek, Barbara Tudek, Ryszard Olinski
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115558 (2014)
The ethiology of colon cancer is largely dependent on inflammation driven oxidative stress. The analysis of 8-oxodeoxyguanosine (8-oxodGuo) level in leukocyte DNA of healthy controls (138 individuals), patients with benign adenomas (AD, 137 individua
Externí odkaz:
https://doaj.org/article/1e50a521f9ac4578868380d02876849d
Publikováno v:
Nucleic Acids Research
Nucleic acids research 48(14), 8128-8145 (2020). doi:10.1093/nar/gkaa541
Nucleic acids research 48(14), 8128-8145 (2020). doi:10.1093/nar/gkaa541
Nucleic acids research / Special publication 48(14), 8128 - 8145 (2020). doi:10.1093/nar/gkaa541
The eukaryotic replisome must faithfully replicate DNA and cope with replication fork blocks and stalling, while simultaneously promoting sister chr
The eukaryotic replisome must faithfully replicate DNA and cope with replication fork blocks and stalling, while simultaneously promoting sister chr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8948fcbaefad567a4b3b5dd7df053c3f
The eukaryotic replisome must faithfully replicate DNA and cope with replication fork blocks and stalling, while simultaneously promoting sister chromatid cohesion. Ctf18-RFC is an alternative PCNA loader that links all these processes together by an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f971eca42a786a042dce2fede06a99c6
https://doi.org/10.1101/808840
https://doi.org/10.1101/808840
Autor:
Somayeh Shahmoradi Ghahe, Milena Bazlekowa, Maciej Baginski, Agnieszka Miazga, Krzysztof Woźniak, Adam Mieczkowski, Roman Gajda, Barbara Tudek, Alicja Winczura, Jacek Wójcik
Publikováno v:
Tetrahedron Letters. 57:743-746
We report a mild and efficient approach to the optically pure 6H-oxazolo[3,2-f]pyrimidine-5,7-dione scaffold via the unexpected rearrangement and ring contraction of 2,3-dihydropyrimido[6,1-b][1,5,3]dioxazepine-7,9(5H,8H)-diones derived from nucleosi
Autor:
Alicja Winczura
Publikováno v:
DNA Repair and Replication ISBN: 9780429464744
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dab1a338faa2fc421afda21af09bbce
https://doi.org/10.1201/9780429464744-5
https://doi.org/10.1201/9780429464744-5
Publikováno v:
Toxicology and Industrial Health. 32:801-808
We investigated the relationship between dibutyl phthalate (DBP)-induced hypomethylation of the c-Myc promoter region (as evident in our early study) and the expression of c-Myc and DNMT1 genes (at messenger RNA (mRNA) and protein level) in the rat l
Autor:
Krzysztof Roszkowski, Ryszard Olinski, Zbigniew Banaszkiewicz, Barbara Tudek, Elżbieta Speina, Marek Foksinski, Agnieszka Siomek, Daniel Gackowski, Ewa Wisniewska, Alicja Winczura, Andrzej Marszałek, Tomasz Dziaman, Rafal Rozalski
Publikováno v:
International Journal of Cancer. 134:376-383
The aim of this work was to answer the question whether the broad range of parameters which describe oxidative stress and oxidatively damaged DNA and repair are appropriate prognosis factors of colon cancer (CRC) patients survival? The following para
Autor:
Wojciech Niedzwiedz, Andrew N. Blackford, Jadwiga Nieminuszczy, Alicja Winczura, Ronan Broderick
Publikováno v:
Nature communications
During mitosis, sister chromatids must be faithfully segregated to ensure that daughter cells receive one copy of each chromosome. However, following replication they often remain entangled. Topoisomerase IIα (TOP2A) has been proposed to resolve suc