Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Alicja Krzyśko"'
Autor:
Patrycja Wińska, Łukasz Widło, Elżbieta Senkara, Mirosława Koronkiewicz, Jarosław M. Cieśla, Alicja Krzyśko, Katarzyna Skierka, Joanna Cieśla
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Thymidylate synthase (TS), dihydrofolate reductase (DHFR), and serine hydroxymethyltransferase (SHMT) constitute the thymidylate synthesis cycle providing thymidylate for DNA synthesis and repair. Our previous studies indicated that TS and DHFR are t
Externí odkaz:
https://doaj.org/article/7996ee4219e6416abfab7151045eb4d9
Autor:
Mirosława Koronkiewicz, Alicja Krzyśko, Maria Bretner, Jarosław M. Cieśla, Patrycja Wińska, Joanna Cieśla, Katarzyna Skierka, Łukasz Widło
Publikováno v:
Anticancer Research. 39:3531-3542
Background/aim Recently, we demonstrated the ability of inhibitors of protein kinase 2 (casein kinase II; CK2) to enhance the efficacy of 5-fluorouracil, a thymidylate synthase (TYMS)-directed drug for anticancer treatment. The present study aimed to