Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Alicja Józkowicz"'
Autor:
Urszula Florczyk-Soluch, Katarzyna Polak, Sarka Jelinkova, Iwona Bronisz-Budzyńska, Reece Sabo, Subhashini Bolisetty, Anupam Agarwal, Ewa Werner, Alicja Józkowicz, Jacek Stępniewski, Krzysztof Szade, Józef Dulak
Publikováno v:
Skeletal Muscle, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Background Adult muscle-resident myogenic stem cells, satellite cells (SCs), that play non-redundant role in muscle regeneration, are intrinsically impaired in Duchenne muscular dystrophy (DMD). Previously we revealed that dystrophic SCs exp
Externí odkaz:
https://doaj.org/article/726a69ef7b32411b9f36f14dae252c48
Autor:
Patryk Chudy, Jakub Kochan, Mateusz Wawro, Phu Nguyen, Monika Gorczyca, Aliaksandra Varanko, Aleksandra Retka, Swati Sweta Ghadei, Emilija Napieralska, Anna Grochot-Przęczek, Krzysztof Szade, Lea-Sophie Berendes, Julien Park, Grzegorz Sokołowski, Qiuliyang Yu, Alicja Józkowicz, Witold N. Nowak, Wojciech Krzeptowski
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103247- (2024)
Heme oxygenase-1 (HO-1, HMOX1) degrades heme protecting cells from heme-induced oxidative damage. Beyond its well-established cellular functions, heme has emerged as a stabilizer of G-quadruplexes. These secondary DNA structures interfere with DNA re
Externí odkaz:
https://doaj.org/article/b94f9795aec742e8937b6667f9efc1b6
Autor:
Gracjan Wątor, Maria Kołton-Wróż, Paweł Wołkow, Łukasz Bełch, Piotr Chłosta, Joanna Szpor, Agnieszka Klimkowska, Katarzyna Nejman, Alicja Józkowicz, Aleksandra Piechota-Polańczyk, Krzysztof Okoń
Publikováno v:
Polish Journal of Pathology, Vol 74, Iss 4, Pp 265-270 (2024)
Prostate cancer (PC) is one of the most common cancers in males. A significant proportion of PCs bear TMPRSS2-ETS translocation and overexpress ERG transcription factor, allowing classification into ERG+ and ERG– groups, which differ in several fea
Externí odkaz:
https://doaj.org/article/7e552c7d6ccc44c7bca3a24e4c48f843
Autor:
Paulina Podkalicka, Olga Mucha, Katarzyna Kaziród, Krzysztof Szade, Jacek Stępniewski, Liudmyla Ivanishchuk, Hirofumi Hirao, Ewelina Pośpiech, Alicja Józkowicz, Jerzy W. Kupiec-Weglinski, Józef Dulak, Agnieszka Łoboda
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-19 (2022)
Abstract Although Duchenne muscular dystrophy (DMD) primarily affects muscle tissues, the alterations to systemic metabolism manifested in DMD patients contribute to the severe phenotype of this fatal disorder. We propose that microRNA-378a (miR-378)
Externí odkaz:
https://doaj.org/article/31f8767de0804f9ea3cdfb34755154d9
Autor:
Anna Kusienicka, Maciej Cieśla, Karolina Bukowska-Strakova, Witold Norbert Nowak, Iwona Bronisz-Budzyńska, Agnieszka Seretny, Monika Żukowska, Mateusz Jeż, Jan Wolnik, Alicja Józkowicz
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 36, Iss , Pp 100865- (2023)
Slow-cycling cancer cells (SCC) contribute to the aggressiveness of many cancers, and their invasiveness and chemoresistance pose a great therapeutic challenge. However, in melanoma, their tumor-initiating abilities are not fully understood. In this
Externí odkaz:
https://doaj.org/article/cd6a55bb5ef742f28e23512a57f3076c
Autor:
Iwona Bronisz-Budzyńska, Magdalena Kozakowska, Katarzyna Pietraszek-Gremplewicz, Magdalena Madej, Alicja Józkowicz, Agnieszka Łoboda, Józef Dulak
Publikováno v:
Cells, Vol 11, Iss 20, p 3321 (2022)
Increased oxidative stress can slow down the regeneration of skeletal muscle and affect the activity of muscle satellite cells (mSCs). Therefore, we evaluated the role of the NRF2 transcription factor (encoded by the Nfe2l2 gene), the main regulator
Externí odkaz:
https://doaj.org/article/dad9ac307438475ca3f64aca55f2b834
Autor:
Agata Szade, Krzysztof Szade, Witold N Nowak, Karolina Bukowska‐Strakova, Lucie Muchova, Monika Gońka, Monika Żukowska, Maciej Cieśla, Neli Kachamakova‐Trojanowska, Marzena Rams‐Baron, Alicja Ratuszna, Józef Dulak, Alicja Józkowicz
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 12, Pp 1-17 (2019)
Abstract Granulocyte colony‐stimulating factor (G‐CSF) is used in clinical practice to mobilize cells from the bone marrow to the blood; however, it is not always effective. We show that cobalt protoporphyrin IX (CoPP) increases plasma concentrat
Externí odkaz:
https://doaj.org/article/52efe050018e4b229e7f380069e8c94f
Autor:
Iwona Bronisz-Budzyńska, Katarzyna Chwalenia, Olga Mucha, Paulina Podkalicka, Karolina-Bukowska-Strakova, Alicja Józkowicz, Agnieszka Łoboda, Magdalena Kozakowska, Józef Dulak
Publikováno v:
Skeletal Muscle, Vol 9, Iss 1, Pp 1-17 (2019)
Abstract Duchenne muscular dystrophy (DMD) is a genetic disease evoked by a mutation in the dystrophin gene. It is associated with progressive muscle degeneration and increased inflammation. Up to this date, mainly anti-inflammatory treatment is avai
Externí odkaz:
https://doaj.org/article/175c5c5bbe5442d28ac094fd7588e154
Autor:
Aleksandra Kopacz, Damian Klóska, Bartosz Proniewski, Dominik Cysewski, Nicolas Personnic, Aleksandra Piechota-Polańczyk, Patrycja Kaczara, Agnieszka Zakrzewska, Henry Jay Forman, Józef Dulak, Alicja Józkowicz, Anna Grochot-Przęczek
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
Premature senescence, a death escaping pathway for cells experiencing stress, is conducive to aging and cardiovascular diseases. The molecular switch between senescent and apoptotic fate remains, however, poorly recognized. Nrf2 is an important trans
Externí odkaz:
https://doaj.org/article/11510aa4019948e6b0a2e102510bc30a
Autor:
Jerzy Kotlinowski, Karolina Bukowska-Strakova, Agnieszka Koppolu, Joanna Kosińska, Natalia Pydyn, Piotr Stawinski, Mateusz Wilamowski, Witold Nowak, Alicja Józkowicz, Jarosław Baran, Rafał Płoski, Jolanta Jura
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
NF-κB signaling, acting through NFKB1 dependent canonical and NFKB2 dependent non-canonical pathways plays a critical role in inflammatory and immune responses. Recent studies have associated mutations in these two genes with a common variable immun
Externí odkaz:
https://doaj.org/article/18cabc4d5cf54f21b793b28ec12f5a51