MYC Dysregulates Mitosis, Revealing Cancer Vulnerabilities

Autor: Julia Rohrberg, Daniel Van de Mark, Meelad Amouzgar, Joyce V. Lee, Moufida Taileb, Alexandra Corella, Seda Kilinc, Jeremy Williams, Marie-Lena Jokisch, Roman Camarda, Sanjeev Balakrishnan, Rama Shankar, Alicia Zhou, Aaron N. Chang, Bin Chen, Hope S. Rugo, Sophie Dumont, Andrei Goga

Publikováno v: Cell Reports, Vol 30, Iss 10, Pp 3368-3382.e7 (2020)

Summary: Tumors that overexpress the MYC oncogene are frequently aneuploid, a state associated with highly aggressive cancers and tumor evolution. However, how MYC causes aneuploidy is not well understood. Here, we show that MYC overexpression induce

Externí odkaz: https://doaj.org/article/2a58f33465c64c2095456ecd5652ebd7

Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps

Autor: Ricardo A. Verdugo, Palmira Granados Moreno, Amy C. Sturm, Alicia Zhou, Masahiro Kanai, Mary K. Balaconis, Charles N. Rotimi, J. Brent Richards, Elisabeth Widen, Saskia C. Sanderson, Anna C. F. Lewis, Genevieve L. Wojcik, Cristen J. Willer, Bartha Maria Knoppers, Samuli Ripatti, Kazuto Kato, Chani J. Hodonsky, Adebowale Adeyemo, Deanna R. Darnes, Alicia R. Martin, Segun Fatumo, Yukinori Okada, Michael Inouye, Michelle N. Meyer, Lucas Richter, Mark I. McCarthy

Publikováno v: Nature Medicine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4788e7de4605894f048f42e90bd802bd
https://doi.org/10.1038/s41591-021-01549-6

Hitting Purchase: The Influence of Social and Demographic Variables on Fast Fashion Consumers

Autor: Alicia Zhou

Publikováno v: Journal of Student Research. 11

With an average annual growth rate of around 11.68%, the fast fashion industry is expanding immensely. Increasing sales of affordable yet trendy clothes are driven by the rising youth population, boosting the fast fashion market. Previous research on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c88b868fbda4305f9ac3fb0832a49e76
https://doi.org/10.47611/jsrhs.v11i3.2882

A Human Settlement Composite Index (HSCI) Derived from Nighttime Luminosity Associated with Imperviousness and Vegetation Indexes

Autor: Ting Ma, Tao Xu, Lin Huang, Alicia Zhou

Publikováno v: Remote Sensing, Vol 10, Iss 3, p 455 (2018)

Satellite-derived nighttime light data have been increasingly used for studying urbanization and socioeconomic dynamics, because there are notable quantitative relationships between anthropogenic nocturnal radiance and the degree of human activity ov

Externí odkaz: https://doaj.org/article/44457f55882d4ef78b2ce86ccc32e43b

The All of Us Research Program: Data quality, utility, and diversity

Autor: Andrea H. Ramirez, Lina Sulieman, David J. Schlueter, Alese Halvorson, Jun Qian, Francis Ratsimbazafy, Roxana Loperena, Kelsey Mayo, Melissa Basford, Nicole Deflaux, Karthik N. Muthuraman, Karthik Natarajan, Abel Kho, Hua Xu, Consuelo Wilkins, Hoda Anton-Culver, Eric Boerwinkle, Mine Cicek, Cheryl R. Clark, Elizabeth Cohn, Lucila Ohno-Machado, Sheri D. Schully, Brian K. Ahmedani, Maria Argos, Robert M. Cronin, Christopher O’Donnell, Mona Fouad, David B. Goldstein, Philip Greenland, Scott J. Hebbring, Elizabeth W. Karlson, Parinda Khatri, Bruce Korf, Jordan W. Smoller, Stephen Sodeke, John Wilbanks, Justin Hentges, Stephen Mockrin, Christopher Lunt, Stephanie A. Devaney, Kelly Gebo, Joshua C. Denny, Robert J. Carroll, David Glazer, Paul A. Harris, George Hripcsak, Anthony Philippakis, Dan M. Roden, Brian Ahmedani, Christine D. Cole Johnson, Habib Ahsan, Donna Antoine-LaVigne, Glendora Singleton, Eric Topol, Katie Baca-Motes, Steven Steinhubl, James Wade, Mark Begale, Praduman Jain, Scott Sutherland, Beth Lewis, Melissa Behringer, Ali G. Gharavi, Louise Bier, Murray H. Brilliant, Narayana Murali, Scott Joseph Hebbring, Dorothy Farrar-Edwards, Elizabeth Burnside, Marc K. Drezner, Amy Taylor, Veena Channamsetty, Wanda Montalvo, Yashoda Sharma, Carmen Chinea, Nancy Jenks, Steve Thibodeau, Beverly Wilson Holmes, Eric Schlueter, Ever Collier, Joyce Winkler, John Corcoran, Nick D’Addezio, Martha Daviglus, Robert Winn, Dan Roden, Joshua Denny, Kim Doheny, Debbie Nickerson, Evan Eichler, Gail Jarvik, Gretchen Funk, Heidi Rehm, Niall Lennon, Sekar Kathiresan, Stacey Gabriel, Richard Gibbs, Edgar M. Gil Rico, Joannie Grand, Paul Harris, Elizabeth Shenkman, William R. Hogan, Priscilla Igho-Pemu, Cliff Pollan, Milena Jorge, Sally Okun, Jordan Smoller, Shawn N. Murphy, Margaret Elizabeth Ross, Rainu Kaushal, Eboni Winford, Febe Wallace, Vik Kheterpal, Akinlolu Ojo, Francisco A. Moreno, Irving Kron, Rachele Peterson, Usha Menon, Patricia Watkins Lattimore, Noga Leviner, Juno Obedin-Maliver, Mitchell Lunn, Lynda Malik-Gagnon, Lara Mangravite, Adria Marallo, Oscar Marroquin, Shyam Visweswaran, Steven Reis, Gailen Marshall, Patrick McGovern, Deb Mignucci, John Moore, Fatima Munoz, Gregory Talavera, George T. O'Connor, Christopher O'Donnell, Greg Orr, Fornessa Randal, Andreas A. Theodorou, Eric Reiman, Mercedita Roxas-Murray, Louisa Stark, Ronnie Tepp, Alicia Zhou, Scott Topper, Rhonda Trousdale, Phil Tsao, Lisa Weidman, Scott T. Weiss, David Wellis, Jeffrey Whittle, Amanda Wilson, Stephan Zuchner, Michael E. Zwick

Publikováno v: Patterns. 3:100570

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f18fa0113f46037c5495d8e969b6fae2
https://doi.org/10.1016/j.patter.2022.100570