Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alicia Vagts"'
Publikováno v:
Proceedings of the National Academy of Sciences. 99:5710-5715
Phosphorylation regulates the function of ligand-gated ion channels such as the N- methyl d -aspartate (NMDA) receptor. Here we report a mechanism for modulation of the phosphorylation state and function of the NMDA receptor via an inhibitory scaffol
Publikováno v:
Proceedings of the National Academy of Sciences. 94:13804-13809
The PKC1–MPK1 pathway in yeast functions in the maintenance of cell wall integrity and in the stress response. We have identified a family of genes that are putative regulators of this pathway. WSC1 , WSC2 , and WSC3 encode predicted integral membr
Autor:
Donna Nikanjam, Claire Thornton, Alicia Vagts, Khanhky Phamluong, Rami Yaka, Ken Luong, Ka-Choi Tang, Dorit Ron
Publikováno v:
The Journal of biological chemistry. 279(30)
Efficient signaling requires accurate spatial and temporal compartmentalization of proteins. RACK1 is a scaffolding protein that fulfils this role through interaction of binding partners with one of its seven WD40 domains. We recently identified the
Publikováno v:
Alcoholism, clinical and experimental research. 27(10)
Background: Previously, we found that acute ethanol induces the translocation of the scaffolding protein RACK1 to the nucleus. Recently, we found that nuclear RACK1 mediates acute ethanol induction of immediate early gene c-fos expression. Alteration
Autor:
Ming-Hong Xie, Bernard Chow, James Lee, Audrey Goddard, Daryl T. Baldwin, Yisheng Jin, Kevin P. Baker, Sherry Heldens, Guoying Yu, Paul J. Godowski, Jean Yuan, Christopher Grimaldi, Jennifer Singh, Alicia Vagts, Clarissa Chui, Dongzhou Liao, Bethanne Deuel, Austin L. Gurney, Min Zhang, Daniel G. Yansura, David Wieand, Patrick Dowd, William I. Wood, Qimin Gu, Lhney Lewis, Somasekar Seshagiri, Jill Schoenfeld, Kathryn Woods, Richard Vandlen, Laura Klimowski, Evangeline Abaya, Zemin Zhang, Melanie R. Mark, Jeremy Stinson, Edward P. Robbie, Hok Seon Kim, Victoria Smith, Craig Crowley, Jessica Foster, Laura Simmons, Bridget Currell, Stephanie Johnson, Colin K. Watanabe, Dan L. Eaton, Jennifer Brush, Jian Chen, Hilary Clark, Sothy Yi, Philip E. Hass, Celina Sanchez, Arthur J Huang
A large-scale effort, termed the Secreted Protein Discovery Initiative (SPDI), was undertaken to identify novel secreted and transmembrane proteins. In the first of several approaches, a biological signal sequence trap in yeast cells was utilized to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85bfd6259edc7f041ff31d6f8b811d17
https://europepmc.org/articles/PMC403697/
https://europepmc.org/articles/PMC403697/
Publikováno v:
Molecular pharmacology. 62(2)
Scaffolding proteins such as receptor for activated C kinase (RACK) 1 are involved in the targeting of signaling proteins and play an important role in the regulation of signal transduction cascades. Recently, we found that in cultured cells and in v
Autor:
Alicia Vagts, Ming-Hong Xie, Jennifer Brush, Kenneth J. Hillan, Audrey Goddard, Patrick Dowd, Ilona Holcomb, Arthur J Huang, Austin L. Gurney, Jie Liang, Qimin Gu, Jessica Foster, Bethanne Deuel
Publikováno v:
Cytokine. 11(10)
We have identified a novel fibroblast growth factor, FGF-19, the most distant member of the FGF family described to date. FGF-19 is a high affinity, heparin dependent ligand for FGFR4 and is the first member of the FGF family to show exclusive bindin
Publikováno v:
The Journal of biological chemistry. 274(38)
Protein kinase C (PKC) isozymes move upon activation from one intracellular site to another. PKC-binding proteins, such as receptors for activated C kinase (RACKs), play an important role in regulating the localization and diverse functions of PKC is