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pro vyhledávání: '"Alicia Todd"'
Publikováno v:
Journal of Molecular Biology. 367:770-787
The endoplasmic reticulum HSP70 chaperone BiP/Kar2p is both the sensor for the unfolded protein response (UPR) in the yeast Saccharomyces cerevisiae and a target of transcriptional up-regulation by this signaling pathway. In this study, the molecular
Publikováno v:
Journal of Biological Chemistry. 274:29850-29857
BiP, a resident endoplasmic reticulum member of the HSP70 family of molecular chaperones, associates transiently with a wide variety of newly synthesized exocytotic proteins. In addition to immunoglobulin heavy and light chains, the first natural sub