Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Alicia Saura"'
Autor:
Albano H. Tenaglia, Lucas A. Luján, Diego N. Ríos, Cecilia R. Molina, Victor Midlej, Paula A. Iribarren, María A. Berazategui, Alessandro Torri, Alicia Saura, Damián O. Peralta, Macarena Rodríguez-Walker, Elmer A. Fernández, Juan P. Petiti, Marianela C. Serradell, Pablo R. Gargantini, Tim Sparwasser, Vanina E. Alvarez, Wanderley de Souza, Hugo D. Luján
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The genomes of most protozoa encode families of variant surface antigens. In some parasitic microorganisms, it has been demonstrated that mutually exclusive changes in the expression of these antigens allow parasites to evade the host’s im
Externí odkaz:
https://doaj.org/article/d049b6259f2c4206b06f3bf7ce1aad2b
Autor:
Bertrand Bellier, Alicia Saura, Lucas A. Luján, Cecilia R. Molina, Hugo D. Luján, David Klatzmann
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
An ideal protective vaccine against SARS-CoV-2 should not only be effective in preventing disease, but also in preventing virus transmission. It should also be well accepted by the population and have a simple logistic chain. To fulfill these criteri
Externí odkaz:
https://doaj.org/article/358d2206ce0f4133aa9e7ac0a3412f92
Autor:
Marianela C. Serradell, Lucía L. Rupil, Román A. Martino, César G. Prucca, Pedro G. Carranza, Alicia Saura, Elmer A. Fernández, Pablo R. Gargantini, Albano H. Tenaglia, Juan P. Petiti, Renata R. Tonelli, Nicolás Reinoso-Vizcaino, José Echenique, Luciana Berod, Eliane Piaggio, Bertrand Bellier, Tim Sparwasser, David Klatzmann, Hugo D. Luján
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Giardia lamblia express a dense coat of variant-specific surface proteins (VSPs) on trophozoites that protects the parasite inside the host´s intestine. Here the authors show that stability and immunomodulatory properties of VSPs can be exploited to
Externí odkaz:
https://doaj.org/article/e1faa7844c394e018f3b0bfaf2625985
Autor:
Albano H. Tenaglia, Lucas A. Luján, Diego N. Ríos, Victor Midlej, Paula A. Iribarren, Cecilia R. Molina, M. Agustina Berazategui, Alessandro Torri, Alicia Saura, Damián O. Peralta, Macarena Rodríguez-Walker, Elmer A. Fernández, Juan P. Petiti, Marianela C. Serradell, Pablo R. Gargantini, Vanina E. Alvarez, Wanderley de Souza, Hugo D. Luján
The genomes of most protozoa encode families of variant surface antigens, whose mutually exclusive changes in expression allow parasitic microorganisms to evade the host immune response1,2. It is widely assumed that antigenic variation in protozoan p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3971990d6909c17157bee4c13c6a92ca
https://doi.org/10.1101/2022.06.21.497077
https://doi.org/10.1101/2022.06.21.497077
Autor:
Macarena Rodríguez-Walker, Cecilia R. Molina, Lucas A. Luján, Alicia Saura, Verónica M. Baronetto, Jon Jerlström-Hultqvist, Staffan G. Svärd, Elmer A. Fernández, Hugo D. Luján
Giardia lamblia encode several families of cysteine-rich proteins. Among these families are the Variant-specific Surface Proteins (VSPs), which are involved in the process of antigenic variation. In addition to VSPs, other Cys-rich proteins have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e29ef496e927fed7e71e0cedb52071ce
https://doi.org/10.1101/2022.03.07.483299
https://doi.org/10.1101/2022.03.07.483299
Autor:
Sascha, Krakovka, Farahnaz, Ranjbarian, Lucas A, Luján, Alicia, Saura, Nicolai B, Larsen, Alejandro, Jiménez-González, Anna, Reggenti, Hugo D, Luján, Staffan G, Svärd, Anders, Hofer
Publikováno v:
The Journal of biological chemistry. 298(6)
Giardiasis is a diarrheal disease caused by the unicellular parasite Giardia intestinalis, for which metronidazole is the main treatment option. The parasite is dependent on exogenous deoxyribonucleosides for DNA replication and thus is also potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a566d6307b17ffea5b07b45bd56663d2
https://pubmed.ncbi.nlm.nih.gov/35568200
https://pubmed.ncbi.nlm.nih.gov/35568200
Publikováno v:
Bellier, Bertrand, Saura, Alicia ORCID: https://orcid.org/0000-0003-1537-506X , Luján, Lucas A. ORCID: https://orcid.org/0000-0003-4235-4301 , Molina, Cecilia R., Luján, Hugo Daniel ORCID: https://orcid.org/0000-0002-3797-8315 and Klatzmann, David (2022) A Thermostable Oral SARS-CoV-2 Vaccine Induces Mucosal and Protective Immunity. Frontiers in Immunology, 13. ISSN 1664-3224
An ideal protective vaccine against SARS-CoV-2 should not only be effective in preventing disease, but also in preventing virus transmission. It should also be well accepted by the population and have a simple logistic chain. To fulfill these criteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a952a8c207cccf1f630f804032693693
https://doi.org/10.1101/2021.09.09.459634
https://doi.org/10.1101/2021.09.09.459634
Autor:
César G. Prucca, Hugo D. Lujan, Pedro Gabriel Carranza, Staffan G. Svärd, Pablo Rubén Gargantini, Alicia Saura, Alessandro Torri
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 81:32-43
During evolution, parasitic microorganisms have faced the challenges of adapting to different environments to colonize a variety of hosts. Giardia lamblia, a common cause of intestinal disease, has developed fascinating strategies to adapt both outsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28065eb195f72bb194381b2d6aef59f1
https://doi.org/10.1016/j.biocel.2016.10.010
https://doi.org/10.1016/j.biocel.2016.10.010
Autor:
Alicia Saura, Lucía Lara Rupil, Hugo D. Lujan, Sergio Rafael Oms, Luciana Berod, Marianela C. Serradell, Tim Sparwasser, Pablo Rubén Gargantini
Publikováno v:
Infection and immunity
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Giardiasis is one of the most common human intestinal diseases worldwide. Several experimental animal models have been used to evaluate Giardia infections, with gerbils (Meriones unguiculatus) being the most valuable model due to their high susceptib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de6872c84f102e7346e0a062b53b30f
https://hdl.handle.net/10033/621403
https://hdl.handle.net/10033/621403
Autor:
Marianela del Carmen. Serradell, Paulina Furlán, Pablo Rubén Gargantini, Alicia Saura, Hugo D. Lujan, M. Faya, Lucía Lara Rupil
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
NPJ Vaccines
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
NPJ Vaccines
Giardia lamblia is a human intestinal parasite and one of the most frequent enteric pathogen of companion animals. Clinical manifestations of giardiasis, such as diarrhoea, anorexia, weight loss and lethargy, have been associated with Giardia infecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9724207ea1b0254551b71db5230ded89
https://www.nature.com/articles/npjvaccines201618
https://www.nature.com/articles/npjvaccines201618